Routine heart CT scanning is not warranted after stenting for left main coronary artery disease, trial results indicate

An analysis of patient-operated ECGs from the EAST—AFNET 4 trial revealed: A low AF burden below 6% in the first year of early rhythm control therapy was associated with low cardiovascular event rates during the subsequent 4 years of follow-up. Patients with a higher AF burden on early rhythm control suffered more AF-related events. The findings were presented by AFNET board member Prof. Ulrich Schotten, Maastricht University, in a hotline session at the annual congress of the European Society of Cardiology (ESC) in Madrid.

Cervical cancer remains one of the most common malignancies in women, ranking as the fourth most prevalent cancer worldwide. Most cases are caused by high-risk strains of human papillomavirus (HPV), particularly HPV16 and HPV18.

Olezarsen decreased levels of triglycerides compared with placebo in patients with moderate hypertriglyceridemia and elevated cardiovascular risk, according to a late-breaking trial presented in a Hot Line session at the ESC Congress 2025 and simultaneously published in the American Heart Journal.

Pulsed field ablation did not have superior efficacy to radiofrequency ablation in patients with drug-resistant paroxysmal (intermittent) atrial fibrillation, according to results from a late-breaking trial presented in a Hot Line session at the ESC Congress 2025.

Dual antiplatelet therapy after cardiac bypass surgery is no more effective than acetylsalicylic acid alone and also increases the risk of serious bleeding. This is shown in a study by researchers at Karolinska Institutet and the University of Gothenburg published in the journal the New England Journal of Medicine.

Aficamten treatment was associated with significant improvements in exercise capacity and symptoms compared with metoprolol in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM), according to late-breaking research presented in a Hot Line session at ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.

A suspected perpetrator who can barely remember his name, several traffic violations committed by a woman in her mid-fifties who is completely unreasonable and doesn't understand her behavior—should such cases be brought before a court? And how does the state deal with people who commit acts of violence without meaning to?

It has long been known that the brain preferentially processes information that we focus our attention on—a classic example is the so-called cocktail party effect.

Swedish-speaking Ostrobothnia in Finland stands out as a potential Blue Zone, thanks to factors such as long life expectancy, good health and a lifestyle resembling those in well-known Blue Zones. Åland, which boasts the highest life expectancy and best health, fails to meet the lifestyle principles of Blue Zones, except when it comes to providing a pleasant environment, according to a study from Åbo Akademi University.

Among individuals with cardiovascular disease or high cardiovascular risk and uncontrolled hypertension on multiple anti-hypertensive agents, a single subcutaneous dose of zilebesiran 300 mg led to a 5-mmHg reduction in systolic blood pressure at Month 3 compared with placebo, a difference that did not reach statistical significance. These results were presented as a late-breaking trial in a Hot Line session today at ESC Congress 2025.

In-hospital initiation of dapagliflozin did not significantly reduce the short-term risk of cardiovascular death or worsening heart failure (HF) in patients admitted for HF, although positive effects were seen when combining trial data, according to late-breaking research presented in a Hot Line session at ESC Congress 2025. Findings were also published in the journal Circulation.

Adding digital twin-guided ablation to a standard ablation technique improved outcomes in patients with persistent atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session at the ESC Congress 2025.

Noninferiority was not demonstrated between immediate and staged complete revascularization in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease undergoing percutaneous coronary intervention (PCI), according to late-breaking research presented in a Hot Line session at the ESC Congress 2025 and simultaneously published in The Lancet.

Discontinuing oral anticoagulation (OAC) therapy resulted in a lower risk of a composite of stroke, systemic embolism or major bleeding than continuing OAC therapy in patients who had successful ablation for atrial fibrillation at least 12 months previously, according to results from a late-breaking trial presented in a Hot Line session at ESC Congress 2025 and simultaneously published in the Journal of the American Medical Association.

Home-based hypertension care led to reductions in systolic blood pressure and improvements in hypertension control in South Africa, according to late-breaking research presented in a Hot Line session at the ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.

Noninferiority was not demonstrated for death and ischemic events between P2Y12 inhibitor monotherapy and dual antiplatelet therapy (DAPT) given for 12 months after stenting in patients with acute coronary syndromes (ACS), according to late-breaking research presented in a Hot Line session at the ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.

There was no benefit to modulating the intensity of antiplatelet therapy compared with standard antiplatelet therapy in high-risk patients who had undergone complex stenting procedures, according to late-breaking research presented in a Hot Line session at the ESC Congress 2025.

Procedure-related infection rates were similar to reconditioned and new pacemakers, according to late-breaking research presented in a Hot Line session at the ESC Congress 2025.