Single antibody may be responsible for life-threatening reaction to common blood thinner

Is it possible to treat obesity without reducing food intake? A new study co-led by Dr. Antonio Zorzano and Dr. Manuela Sánchez-Feutrie at the Institute for Research in Biomedicine (IRB Barcelona) suggests that this might be a possibility, at least in animal models.

A top health official in Florida vowed Wednesday to end all vaccine mandates in the state, including school requirements, likening the measure to prevent childhood diseases to "slavery."

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents. This novel platform reflects the microenvironment of liver tumors, particularly a functional and perfusable microvasculature that can be embolized. This in vitro tool aligns with the National Institutes of Health (NIH) efforts to reduce animal testing and promote alternative methods, including microfluidic devices that mimic human organs.

Colorectal cancer is unique in having its own microbial "fingerprint," according to new research from the University of East Anglia.

A new study, led by the University of Cambridge in collaboration with Bournemouth University, shows that autistic people identify loneliness, hopelessness, and feelings of worthlessness and failure as key factors underpinning their suicidal feelings. Individuals who highlighted being unable to access the support they needed were more likely to have attempted suicide. Autistic women and gender minorities were disproportionately over-represented among those who struggled to access support.

An MUSC research team reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that contribute to fetal brain inflammation and preterm birth, the latter of which is the leading cause of complications and death in newborns.

Close your eyes and visualize the following: a decadent piece of chocolate cake, a bouquet of fully bloomed red roses, a juicy peach. Hopefully, these mental images produced some form of positive feeling. But is it possible that, despite the feel-good emotions associated with all of them, our brains react differently to food-specific items?

Toddlers assessed during the COVID-19 pandemic had slightly fewer emotional and behavioral problems compared to children assessed before the pandemic, suggesting some toddlers may have shown resilience during this time. This finding comes from a study of over 3,000 children across the United States using data from the Environmental influences on Child Health Outcomes (ECHO) Cohort Consortium collected between September 2009 and July 2023.

Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians in the United States and elsewhere. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.

DermaRite Industries has expanded a voluntary recall of several over-the-counter creams, soaps and sanitizers that may be contaminated with Burkholderia cepacia complex, a type of bacteria that can cause serious infections.

Peer review and the editorial process yield frequent improvements in research abstracts of randomized clinical trial (RCT) reports, according to a research letter published online Sept. 2 in the Annals of Internal Medicine.

The weight-loss drug Wegovy may lower the risk of heart attack, stroke or death more than similar medications, according to new research from its maker, Novo Nordisk.

For children with type 1 diabetes (T1D), glycated hemoglobin (HbA1c) levels are associated with accessibility of modern diabetes technologies and insulin, according to a study published online Aug. 27 in JAMA Network Open.

Taylor Fresh Foods has issued a voluntary recall of its Honey Balsamic Salad Kit after discovering the dressing packets contained undeclared sesame and soy.

Fourteen percent of individuals initiate glucagon-like peptide 1 receptor agonists (GLP-1 RAs) after bariatric surgery, according to a study published online Aug. 27 in JAMA Surgery.

One of the largest Brazilian studies on colorectal cancer has revealed how genetic variations and genetic ancestry can influence the risk of developing the disease. The study, conducted by researchers at Hospital de Amor (formerly Hospital de Câncer de Barretos, in the interior of the state of São Paulo) and other institutions, contributes to understanding the complex genetic reality of a highly mixed population such as Brazil's. It was published in the journal JCO Global Oncology.

Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive. Now, researchers at the University of Illinois Urbana-Champaign have developed a new high-volume method that can rapidly build and test large numbers of antibodies at once. With it, they have already uncovered common aspects of how antibodies bind across variants of a key influenza target protein.

In Brazil, researchers at São Paulo State University (UNESP) conducted experiments on rats and identified that a protein-deficient diet during pregnancy and breastfeeding can compromise the reproductive health of male offspring. A study published in the journal Biology Open found that maternal protein restriction causes changes in the structure and function of the epididymis, an organ in the reproductive system responsible for the maturation and storage of sperm.