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Single-neuron projectomes of macaque prefrontal cortex reveal primate-specific connectivity principle

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  • 2025-07-15 18:50 event
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Single-neuron projectomes of macaque prefrontal cortex reveal primate-specific connectivity principle
In a study published in Cell on July 10, researchers reported the first comprehensive study of whole-brain projectomes of the macaque prefrontal cortex (PFC) at the single-neuron level and revealed the organization of macaque PFC connectivity.

1.878. Microplastics can cause malignant changes in lung cells

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Although the respiratory system is one of the main entry points for microplastics and nanoplastics (MNPs) from the air into the body, little is known about the effects of these tiny particles on the lungs. Researchers at MedUni Vienna have now demonstrated for the first time that MNPs can trigger malignant changes in lung cells that are associated with the development of cancer. The findings are published in the Journal of Hazardous Materials and once again underline the urgent need for action to reduce plastic waste.

1.879. Survey shows cancer anxiety has impact well beyond the individual diagnosed

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A cancer diagnosis is a life-changing event for patients that can cause short- and long-term mental health concerns as they shift to living within a new timeline driven by weeks or months between medical follow-up appointments.

1.880. Family doctor offers tips for summer water safety

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Every year in the U.S., about 4,000 people die by drowning. Children, men and nonwhite people are at the highest risk.

1.881. How Trump's Medicaid work requirements could affect mental health care

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For many people who have a serious mental illness or are recovering from one, trying to get or keep a job may be overwhelming and exhausting.

1.882. Survey finds Americans choose short term relief for neck and back pain

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New survey data from the Orlando Health Spine Center reveals a significant difference among Americans on how to manage neck and back pain. Respondents were split between relying on rest and reduced activity (44%), turning to over-the-counter pain relievers (42%), and hot/cold therapies (29%)—an uncertainty that may be discouraging some from seeking medical guidance.

1.883. How to mitigate damage from gunshot injuries to the brain in children and young adults: Study

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A study presented at the Society of NeuroInterventional Surgery's (SNIS) 22nd Annual Meeting found that almost half of gunshot wound injuries to the brain in children and young adults include penetrating cerebrovascular injuries (PCVIs).

1.884. Record-breaking human imaging project crosses the finish line: Volunteers provide most detailed look inside the body

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In a remarkable achievement that is already impacting how we detect and diagnose disease, UK Biobank has completed the world's largest whole body imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers. These scans, on this scale, show us what is happening in people's bodies as they age so we can understand how, why and when we get sick.

1.885. AI-powered mobile retina tracker screens for diabetic eye disease with 99% accuracy

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A novel AI-powered retina tracker can analyze retinal images with near-perfect accuracy in under one second, according to a study presented at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

1.886. Cancer drug shows promise as treatment for blindness

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Singapore researchers have discovered that a new cancer drug, originally developed at A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB), shows potential as a new treatment approach for two leading causes of blindness worldwide.

1.887. Single-neuron projectomes of macaque prefrontal cortex reveal primate-specific connectivity principle

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In a study published in Cell on July 10, researchers reported the first comprehensive study of whole-brain projectomes of the macaque prefrontal cortex (PFC) at the single-neuron level and revealed the organization of macaque PFC connectivity.

1.888. Implantable cell therapy has potential to restore adrenal function and treat primary adrenal insufficiency

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Adrenal hormone function was restored in animal studies, potentially paving the way for a functional cure for primary adrenal insufficiency in humans, according to research presented by Aspect Biosystems at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

1.889. Protein aggregation inhibitor shows lower levels of cell death and paralysis in mice with acute strokes

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Stroke is said to be the second leading cause of death worldwide after heart disease. To prevent the death of neurons in the brain, a research group led by Osaka Metropolitan University Associate Professor Hidemitsu Nakajima of the Graduate School of Veterinary Science has developed a drug that inhibits a protein involved in cell death.

1.890. Study finds strong link between acromegaly and increased cancer risk

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People with the rare growth hormone disorder acromegaly have a significantly higher risk of developing various types of cancer, often at ages younger than typically seen in the general population, according to a study presented at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

1.891. Dropscreen, ViewAllergy39 not equally effective for detecting allergens, study finds

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DropScreen (DS) and ViewAllergy39 (VA) are not equally effective for detecting specific immunoglobulin (Ig) E involved in pollinosis, according to a study published online in the Journal of Immunoassay and Immunochemistry.

1.892. Genetic tool predicts lithium responsiveness in bipolar disorder patients

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Researchers from the University of Adelaide are hopeful a recent biological discovery could lead to the precision treatment of bipolar disorder (BD).

1.893. Study finds hyperbaric therapy + corticosteroid combo aids sudden sensorineural hearing loss

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Hyperbaric oxygen therapy (HBOT) used in conjunction with corticosteroids aids outcomes for sudden sensorineural hearing loss (SSNHL), according to a study published online in Clinical Otolaryngology.

1.894. Childhood trauma shapes adult stress appraisal and mental health outcomes, research reveals

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University of Leeds psychologists report that stress appraisal and perceived stress act as key conduits linking childhood trauma to adult depression, anxiety, defeat, and entrapment.

1.895. Study suggests teens with obesity may face higher risk of fractures and osteoporosis later in life

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Obesity and type 2 diabetes in adolescence can interfere with bone development, potentially increasing the risk of fractures and osteoporosis later in life, according to a study presented at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

1.896. Study finds key mechanism driving neuroblastoma progression

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A new study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix.

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