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Smoking and biological sex shape healthy bladder tissue evolution, offering clues to cancer risk

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  • 2025-10-08 22:00 event
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Smoking and biological sex shape healthy bladder tissue evolution, offering clues to cancer risk
Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor. However, the biological mechanisms behind these risk factors remain unclear. Since cancer can take decades to develop, it is important to look at healthy tissues to understand the very first steps of the disease, with the goal of improving risk prediction, prevention, and early diagnosis.

26. Experts warn the IV hydration craze may be putting you at risk

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IV hydration spas are popping up across the United States, offering pricey vitamin infusions that promise energy, detox or immune support, but experts warn the science doesn't back up those claims.

27. Halloween candy tips to keep kids' teeth healthy

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Halloween is all about costumes, candy and fun, but all that sugar can take a toll on your child's teeth.

28. 'Immune digital twins' could simulate drug responses without risk

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An international project to create a "digital twin" of the human immune system could help scientists finally tackle grand challenges such as autoimmune disorders and infectious diseases.

29. What's the difference between hot sweat and cold sweat?

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Imagine two scenarios. In the first, you're hiking uphill on a warm day, beads of sweat rolling down your forehead. In the second, you've just remembered you have an exam tomorrow and now the palms of your hands are cold and damp.

30. Breastfeeding for at least six months strengthens immunity in babies, study suggests

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Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune system will improve health outcomes for all infants, including those not breastfed.

31. Late-onset cerebellar ataxia: A genetic avenue uncovered

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Could an anomaly in the developing brain explain motor difficulties occurring decades later in people with rare movement disorders?

32. Improved genetic tool reveals hidden mutations that can drive cancer

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Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.

33. Hidden evolution in sperm raises disease risk for children as men age

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Harmful genetic changes in sperm become substantially more common as men age because some are actively favored during sperm production, new research has revealed.

34. Medicaid innovation models improve care for moms, but design matters

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A new study led by researchers at the Department of Population Medicine–Harvard Pilgrim Health Care Institute, Boston Medical Center, and Boston University School of Public Health finds that how Medicaid programs are designed can make a big difference in the care pregnant and postpartum people receive.

35. Smoking and biological sex shape healthy bladder tissue evolution, offering clues to cancer risk

  • 3 hours ago schedule
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Bladder cancer is one of the most common cancers worldwide. Men are around four times more likely to develop it than women, and smoking is the main known environmental risk factor. However, the biological mechanisms behind these risk factors remain unclear. Since cancer can take decades to develop, it is important to look at healthy tissues to understand the very first steps of the disease, with the goal of improving risk prediction, prevention, and early diagnosis.

36. Rapid kidney test in development for early intervention, simple monitoring

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A simple blood test could reveal kidney disease earlier so more can be done to halt progression, while also allowing better ongoing management of kidney health by simpler monitoring.

37. Long-term impact of excessive gaming on teens revealed in study

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A new study has revealed that 1 in 10 boys may experience internet gaming disorder (IGD) at some point during their formative years, and negative consequences persist for both boys and girls throughout adolescence.

38. Study finds dosing concerns for common anticoagulant in underserved areas

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Blood thinners are often prescribed to prevent life-threatening clots. One type, called direct oral anticoagulants (DOACs), is used to treat a variety of conditions that affect blood vessels, the heart and lungs. But like any medication, they only work if taken and monitored correctly.

39. Individuals with sickle cell disease face long delays to pain care in emergency department

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Most individuals living with sickle cell disease who presented to the emergency department with a pain crisis, known as vaso-occlusive crisis (VOC), were not triaged appropriately according to established national guidelines, reveals a study published today in Blood Advances.

40. Little-known strep bacteria behind growing number of severe infections in Australia

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An under-recognized strep bacterium is causing a growing number of serious infections in Australia, with First Nations Australians disproportionately affected, according to new research published in The Lancet Microbe.

41. Some towns are cutting fluoride from water supplies. Here's what this means for locals' teeth

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Thousands of residents in Dubbo and Wellington, in western New South Wales, haven't had fluoride added to their tap water for nearly seven years.

42. People with bipolar disorder are taking to YouTube to talk about it

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YouTube has become a favorite platform for many people with mental health problems. It is a place where they can share their own experiences and discuss different aspects of living with a diagnosis.

43. What is a 'dopamine detox?' And do I need one?

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Advice about cutting down on dopamine is everywhere right now. From "dopamine fasting" to "anti-dopamine parenting" and even "raw-dogging" flights (going without any screens, books or music), TikTok influencers claim these practices have rewired their brains.

44. Rethinking Alzheimer's: Why this common gene variant is bad for your brain

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The suspected causes of Alzheimer's disease are diverse, and its cures are, today, nonexistent.

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