Social lifetime experiences can have long-lasting effects on mental and brain health

In the brain, it is not only important that nerve cells send signals, but also how quickly they can do so. In order for information to flow smoothly, a kind of biological insulation is necessary. The brain forms specialized cells called oligodendrocytes for this purpose. They coat the long extensions of nerve cells, the axons, with a protective layer of myelin.

Researchers at Children's Hospital of Philadelphia (CHOP) unveiled a novel antibody-drug conjugate (ADC) that shows striking efficacy against cancers that express the anaplastic lymphoma kinase (ALK) protein on the cancer cell surface. The therapy, named CDX0239-PBD, achieved complete and lasting tumor responses in preclinical models of neuroblastoma, rhabdomyosarcoma and colorectal carcinoma, according to findings published in Nature Communications.

A high-sugar, high-fat diet during pregnancy may do more than affect a mom's health—it can also trigger inflammation and gut dysfunction in their children, new research suggests. The study, published in the American Journal of Physiology—Gastrointestinal and Liver Physiology, found that poor maternal nutrition impairs intestinal barrier function in the next generation. The article has been chosen as an APSselect article for September.

German doctors are increasingly prescribing smartphone health apps alongside pills and therapy to patients, marking a growing trend towards digital health care.

Gooder Foods, Inc. is recalling eight lots of its boxed mac and cheese products because they may contain undeclared allergens, federal officials said.

A new study illuminates how some areas of the country have been hit much harder than others by the fentanyl epidemic, which took more than 70,800 lives in 2022 alone.

For most people, swallowing is second nature, but how does it occur, and why do some people have difficulty with it? Researchers at Kyushu University in Japan have started to tackle these questions by developing a mathematical model that recreates the muscle movements of the esophagus that occur during swallowing. The model, reported in Royal Society Open Science, also replicates muscle dynamics seen in various esophageal motility disorders, revealing insights into their underlying causes and opening up new avenues for treatment.

Federal health officials are reviewing safety data on COVID vaccines in pregnant women and children, and may also reconsider recommendations for older adults.

New findings from researchers at UC Irvine show how a simple dietary change that increases fiber intake can reshape gut bacteria to prevent sugar from damaging the liver and causing disease.

"Be kind to yourself" is a piece of advice that's often given to people during difficult times or moments of stress. But for someone who is driven, a perfectionist or facing pressure, the idea of self-compassion can feel uncomfortable. To them, kindness might feel like letting themselves off the hook.

The sound slices through the quiet of the night: a muffled sob, then a hiccup, quickly escalating into a high-pitched, frantic wail. For any parent or caregiver, this is a familiar, urgent call to action. But what is it a call for? Is the baby hungry? In pain? Lonely? Or simply uncomfortable?

A little blue pill is creating a stir in Hollywood—and no, it's not Viagra. It's propranolol, a beta blocker originally designed for heart conditions, that's now making its way into dressing rooms, award ceremonies and even first dates.

Delayed marriage significantly reduces the risk of obesity among urban women in Pakistan, new research has shown.

If young teens use social media to learn about sexual health, it is better if they use sites like YouTube rather than ones like Snapchat, a new study shows.

In a new position paper, the American College of Physicians (ACP) identifies core clinical topics of importance to internal medicine physicians, sets a framework for identifying a streamlined set of core performance measures, and calls for the use of high-quality, evidence-based performance measures to be used nationally across all payers and systems. This is significant because many performance measures currently used are not based on high certainty evidence and are burdensome, with low or no value to patient care.

On Sept. 10, 2025, the nation's attention was riveted by the fatal shooting of the conservative activist Charlie Kirk on a college campus in Utah. At nearly the exact same time, a state away—in Colorado—an active shooting was underway on a high school campus in a sleepy mountain town, leaving two teens in critical condition and the shooter, a fellow student, dead from a self-inflicted gunshot.

A team led by UT Southwestern Medical Center scientists has identified early signals from the immune system that could help predict which cancer patients are most likely to develop harmful side effects from immunotherapy. The findings, published in the Journal for ImmunoTherapy of Cancer, offer a path toward tests to help doctors tailor care for at-risk patients.

More than 100,000 Paris Hilton-branded mini fridges are being recalled because of a risk of fire and burns, federal safety officials announced.