Study finds experimental antibody may reduce fibrosis in chronic kidney disease

After years of progress in reducing malaria cases, Rwanda is confronting a surprising resurgence and signs of treatment resistance that have forced officials to revisit vaccine intervention the country once declined.

Some of our biggest threats can come in the tiniest forms—viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we age. New research from the Stowers Institute for Medical Research is revealing why this tradeoff exists, identifying a common power source driving many immune system responses to pathogens. The findings may potentially lead to new ways to combat inflammation and diseases associated with aging like Alzheimer's, Parkinson's, and cancer.

The CORE-MD (Coordinating Research and Evidence for high-risk Medical Devices) consortium has published new consensus recommendations today in The Lancet Regional Health Europe, that set out scientifically robust methodologies for clinical investigations of high-risk medical devices.

James Madison University and Case Western Reserve University researchers describe a phenomenon they term the Rumpelstiltskin effect, in which the act of receiving a clinical diagnosis itself produces therapeutic benefit independent of medical intervention.

A new study led by Prof. Lynn Chenoweth from UNSW's Center for Healthy Brain Aging (CHeBA) has shown that educating hospital staff in person-centered dementia care leads to better care experiences, greater staff confidence, and improved rehabilitation outcomes for older Australians.

Tuberculosis, or TB, an airborne bacterial respiratory infection, is one of humanity's oldest foes and is today the world's leading cause of death from infectious disease, claiming more than 1.2 million lives each year. The single available vaccine protects young children from severe cases of TB but does little to prevent the spread of disease in adolescents and adults.

Northeastern University professor Raymond Booth first learned about propranolol, a drug developed to treat high blood pressure, in pharmacy school around 1978.

California's late summer COVID surge is showing signs of peaking, but the state's war with the Trump administration over vaccines is just beginning.

"Liquid biopsy" tests using blood samples to screen for multiple types of cancer are attracting much attention, for their potential to catch unseen tumors.

Critics of affirmative action have launched a long-shot appeal aimed at stopping California from requiring training on unconscious bias in every continuing medical education class.

When we recall something familiar or explore a new situation, the brain does not always use the same communication routes.

Deaths following opioid use in England and Wales have nearly doubled in the last decade, with 22.9 deaths per million people in 2012, and 43.8 deaths per million people in 2023. But the true number is likely higher because of a constraint of the data provided by coroners to the Office for National Statistics (ONS).

Pam Thomson-Kai's son Sawyer was just 7 months old when he stopped breathing. He was rushed to hospital, where he was revived and put on a breathing machine. Then the doctors asked his parents whether they could give him a tracheostomy—a surgical procedure to create an opening in the windpipe and allow air to flow to his lungs.

Patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus frequently face anxiety and depression along with chronic physical symptoms. Reported rates of depression range from 15% to 24% and anxiety from 19% to 37% in this population. Women are disproportionately affected, with conditions occurring up to nine times more frequently than in men.

It starts with a sneeze. Someone on the subway didn't cover their mouth and now a cloud of invisible invaders hangs in the air. Before you even step off the train, your immune system has already begun fighting off the threat and protecting you from harm.

For anyone unfortunate enough to have grown up without them, tomatillos might seem tough to approach. They hide inside a papery cloak and tend to hang out in the quietest corners of produce sections in the U.S.—if they show up there at all.

When air conditioning is not available during extreme heat, millions of older adults and other people become vulnerable to cardiac problems and other heat-related illnesses, according to researchers in the Penn State Department of Kinesiology.

U.S. foreign aid cuts could result in over 10 million additional tuberculosis (TB) cases and 2.5 million more deaths in the next years, across 26 countries with high TB burden, found a study by Center for Modeling and Analysis, the U.S., and Stop TB Partnership, Switzerland published in PLOS Global Public Health.