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Study finds immune cells undermine cancer therapy by triggering their own death

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  • 2025-07-23 23:24 event
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Study finds immune cells undermine cancer therapy by triggering their own death
A team of Memorial Sloan Kettering Cancer Center (MSK) researchers have made an important finding about why genetically engineered immune cells sometimes fail to finish the job when given as a cancer treatment. The new discovery sheds light on the tendency of these modified cells to lose power or even self-destruct before fully destroying a tumor. This is a major problem, for example, in chimeric antigen receptor (CAR) T cell therapy.

1.367. US bans vaccine ingredient targeted by anti-vaxxers

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The US health department said Wednesday it would end the use of a vaccine ingredient long targeted by conspiracy theorists over debunked claims it causes autism.

1.368. Scientists use dental floss to deliver vaccines without needles

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Flossing your teeth at least once a day is an essential part of any oral health routine. But it might also one day protect other parts of the body as scientists have created a novel, needle-free vaccine approach using a specialized type of floss.

1.369. Vietnam's hidden burden: Lung cancer caregivers face alarming low resilience

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A newly published study in the European Journal of Oncology Nursing, led by Dr. Thinh Toan Vu at the Center for Innovation in Mental Health with Associate Professors Sasha Fleary, Glen Johnson, and Victoria Ngo, reveals that over half of family caregivers for lung cancer patients in Vietnam report low resilience. This raises urgent concerns about caregiver mental health and the sustainability of informal care within an already overstretched health system.

1.370. Vaccine hesitancy among parents can lead to reduced vaccine coverage

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For her doctoral dissertation, Senior Planning Officer Idil Hussein studied the intentions of Finnish parents in terms of allowing their children to have human papillomavirus (HPV) and influenza vaccines.

1.371. Mental health inequities observed across American Indian and Alaska Native subgroups in California

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While more than 1 in 3 American Indian and Alaska Native adults in California experienced moderate or serious psychological distress in the past year, 61% of the individuals in that group had not seen a medical provider, according to a new study from the UCLA Center for Health Policy Research.

1.372. What to know about Parkinson's disease after Ozzy Osbourne's death

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Heavy metal rocker Ozzy Osbourne died this week at 76, just weeks after his farewell show and about five years after announcing he had Parkinson's disease.

1.373. City diets leave distinct microbial signatures in the human gut, study finds

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A new study shows that the human gut microbiota can pinpoint whether an adult lives in Wuhan or Shiyan, two cities 500 km apart in China's Hubei Province, with 94% accuracy. This microbial signature is strongly linked to each city's characteristic diet.

1.374. Low dose of weight loss drug may improve heart failure symptoms with minimal weight loss

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Low doses of the injectable weight-loss medication semaglutide may improve symptoms of a hard-to-treat type of heart failure. This effect happened through direct action on the heart muscle and blood vessels, despite resulting in no significant weight loss, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions (BCVS 2025). The meeting, held in Baltimore, July 23–26, 2025, offers the latest research on innovations and discovery in cardiovascular science.

1.375. Does your smartwatch say you're stressed? It may often be wrong

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It is impossible to imagine life without the smartwatch for a huge group of people. About 455 million consumers worldwide used a smartwatch in 2024. They are especially popular among young adults (18–34 years old); in this age group, about 40% use a smartwatch.

1.376. Study finds immune cells undermine cancer therapy by triggering their own death

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A team of Memorial Sloan Kettering Cancer Center (MSK) researchers have made an important finding about why genetically engineered immune cells sometimes fail to finish the job when given as a cancer treatment. The new discovery sheds light on the tendency of these modified cells to lose power or even self-destruct before fully destroying a tumor. This is a major problem, for example, in chimeric antigen receptor (CAR) T cell therapy.

1.377. Youth at risk of suicide show early warning signs that adults often miss

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Drawing on a landmark 25-year study that followed Quebec children into adulthood, McGill University researchers have identified two distinct patterns in how suicidal thoughts emerge and the early signs that are often missed.

1.378. Physically restricting mental health patients can often harm them. New study suggests compassion could change that

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Restrictive practices in mental health settings—such as physical restraint and seclusion—are meant to be a last resort, used only when patients pose a risk to themselves or others.

1.379. How germy is the public pool? An infectious disease expert weighs in

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On hot summer days, few things are more refreshing than a dip in the pool. But have you ever wondered if the pool is as clean as that crystal blue water appears?

1.380. TikTok creators perform 'roles' when sharing their hereditary cancer stories, shaping the health information they share

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A new study has explored how people with hereditary cancer identify on TikTok.

1.381. Frail heart patients may benefit from comprehensive prehabilitation strategy

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A multidisciplinary prehabilitation protocol shows promise in reversing frailty and improving outcomes for patients with advanced heart failure who are waiting for surgery.

1.382. Tuna recalled in seven states over listeria fears

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Two types of tuna sold in seven states are being recalled due to listeria concerns.

1.383. Dual-action therapy combines light and iron to target breast cancer cells

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A new study published in Nanotechnology offers new hope for less harmful breast cancer therapy by combining two powerful, non-invasive cancer treatments.

1.384. Newly discovered 'sixth sense' links gut microbes to the brain in real time

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In a breakthrough that reimagines the way the gut and brain communicate, researchers have uncovered what they call a "neurobiotic sense," a newly identified system that lets the brain respond in real time to signals from microbes living in our gut.

1.385. Map-making neurons change even when familiar settings remain exactly the same

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In a new study, Northwestern University neurobiologists have found that the brain's internal GPS changes each time we navigate a familiar, static environment.

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