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Study finds protein target that predicts drug resistance in colon cancer

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  • 2025-10-20 23:08 event
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Study finds protein target that predicts drug resistance in colon cancer
An international team of researchers has uncovered a promising new avenue for treating colorectal cancer, the world's third leading cause of cancer-related deaths. By analyzing patient-specific genetic data, scientists identified a protein system that could predict chemotherapy resistance and open the door to more tailored, effective treatments.

38. Veterans' mental health forged beyond the battlefield, researchers find

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New research shows that veterans' mental health after leaving the military is shaped by more than just combat, with childhood trauma, deployment experiences and gender all influencing post-9/11 veterans' well-being, according to a team at Penn State.

39. Children drive household mpox infections, study reveals

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A study by CUNY SPH doctoral student Raoul Kamadjeu provides important new data on how mpox, especially the Clade Ib strain, transmits within households. The paper is published in The Lancet Infectious Diseases.

40. Scientists discover how cells protect the skin from inflammatory disease—paving the way for new treatments

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Researchers at VIB and Ghent University have uncovered a key mechanism that protects the skin from harmful inflammation. The findings, published in Immunity, could open new avenues for treating chronic skin diseases and other inflammatory disorders.

41. Adverse and positive childhood experience levels in US haven't changed much, study finds

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New research shows that overall, the prevalence of adverse and positive childhood experiences reported by parents of teenagers hasn't changed substantially in the United States in recent years.

42. Examining the long-term effects of common heartburn medications on kidney and cardiovascular health

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A new study from Karolinska Institutet suggests that some widely used heartburn medications may be linked to kidney problems over time. Researchers followed nearly 300,000 patients for up to 15 years to explore how these drugs might affect kidney and heart health.

43. Built-in backup system helps muscles counteract fatigue

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When you're running up stairs or out on a jog, your muscles eventually start to feel heavy and weak. That's fatigue setting in, a sign that the muscles' energy reserves are becoming depleted. But a team of researchers led by Rensselaer Polytechnic Institute (RPI) biology professor Doug Swank, Ph.D., have discovered something surprising: certain muscle fibers have a built-in backup system that fights back against fatigue, potentially helping us keep going when we'd otherwise have to stop.

44. Towards prostheses controlled by the power of thought: Virtual tasks reveal how the brain recalibrates movements

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Researchers at the German Primate Center (DPZ)—Leibniz Institute for Primate Research in Göttingen have discovered that the brain reorganizes itself extensively across several brain regions when it learns to perform movements in a virtual environment with the help of a brain–computer interface. The scientists were thus able to show how the brain adapts when controlling motor prostheses.

45. National poll: 1 in 10 young children play outdoors as little as once a week

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The physical and mental health benefits of outdoor play are well established, but one in 10 parents of preschoolers and toddlers say their child plays outside just once a week or less.

46. Exploring the effect of bedroom ventilation on sleep quality

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Good sleep is key to good health, overall well-being, and optimal cognitive function. Disturbed sleep or lack of sleep can lead to various health issues such as cardiovascular diseases, cancer, and other morbidities, including Alzheimer's disease and obesity.

47. Study finds protein target that predicts drug resistance in colon cancer

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An international team of researchers has uncovered a promising new avenue for treating colorectal cancer, the world's third leading cause of cancer-related deaths. By analyzing patient-specific genetic data, scientists identified a protein system that could predict chemotherapy resistance and open the door to more tailored, effective treatments.

48. Nearly half of Finns with chronic conditions find medication therapy a burden, study finds

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According to a recent study, 44% of people with chronic conditions who responded to a population-based survey experienced medication-related burden (MRB). The burden was most common among people with diabetes, heart disease, rheumatic disease or some other musculoskeletal disorder.

49. New weight loss pill aims to bridge gap in obesity treatments

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An innovative new pill could soon offer a new and affordable weight management treatment, following a successful clinical trial involving University of Bristol researchers. The results are published in a paper titled "A randomized, double-blind, placebo-controlled pilot trial with open-label extension of Sirona, a hydrogel for weight loss" in Obesity.

50. New study maps how we simultaneously process different words

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Trains move through the world's subway stations in a consistent pattern: arriving, stopping, and moving to the next stop—and repeated by other trains throughout the day. A new study by a team of New York University psychology and linguistics researchers finds that our brains work much the same way when processing several words at once—as we routinely do when listening to others speak.

51. College students who experienced family dysfunction as children sometimes turn to alcohol to cope

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College can be a joyful time—of learning, forming lifelong friendships and having fun. But it's not without its challenges. National Collegiate Alcohol Awareness Week, Oct. 19–25, brings attention to the struggles faced by students on campuses across the U.S., calling for increased education and resources.

52. Rise in youth mortality fueled by mental illness, drugs, violence and other preventable causes

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Global mortality continues to fall. Life expectancy has improved to unprecedented levels and deaths in young children have plummeted. Yet for adolescents and young adults, especially those aged 15 to 24, little progress has been made, according to data from the latest Global Burden of Disease study. In parts of North America and eastern Europe, mortality in those aged 15–24 has actually risen in the past decade.

53. Biological mechanism the boosts myelin production in the brain could aid treatments for neurological disorders

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Researchers from Tel Aviv University have discovered a new biological mechanism that enhances the production of myelin—a substance essential for proper brain function and nerve communication.

54. New generation of antibody-drug conjugates shows promise in early-stage HER2-positive breast cancer

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In a landmark moment at the ESMO Congress 2025, pivotal studies have unveiled compelling evidence that a new class of anti-cancer agents—antibody-drug conjugates (ADCs)—can dramatically improve outcomes for patients with early-stage HER2-positive breast cancer.

55. Personalized brain stimulation offers new hope for people with hard-to-treat epilepsy

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Doctors and researchers at the University of Pittsburgh and UPMC have developed a new treatment for epilepsy patients who don't respond to medication and aren't candidates for surgery. Their approach, published in Nature Communications, uses deep brain stimulation (DBS) that is tailored to each patient's unique brain wiring.

56. The fungi living in the body play an important role in health—here's what you should know about the 'mycobiome'

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The "gut microbiome" has become a popular health term in recent years. It's easy to see why, with an abundance of research showing how important the trillions of microbes living in our gut are for health.

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