Study reveals how inhibitory neurons and astrocytes control brain blood flow

A new study published by Cleveland Clinic researchers in Diabetes, Obesity and Metabolism investigating the genetic underpinnings of weight loss response has identified a gene, neurobeachin (NBEA), as a predictor of how individuals respond to GLP-1RAs, the class of medications behind popular treatments like liraglutide and semaglutide.

Researchers at the University of Pittsburgh and Carnegie Mellon University collaborated to create a customized app based on artificial intelligence that may help people with multiple sclerosis track their symptoms—and even predict them.

Accurate removal of tumors is the most critical aspect of cancer surgery, yet it remains a significant challenge in clinical practice. In breast cancer, for example, the positive margin rate—where cancer cells remain at the surgical boundary—can reach up to 35%, often requiring reoperation and increasing the risk of recurrence.

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited condition that can lead to kidney failure. Being able to accurately predict how the disease will progress is very important for selecting the right treatments and providing effective patient counseling. However, the currently available prediction tools aren't very accurate and require MRI images or genetic exams, which are not always available.

As authorities brace for a potential resurgence in bird flu cases this fall, infectious disease specialists warn that the Trump administration's crackdown on undocumented immigrants could hamper efforts to stop the spread of disease.

As far back as the 4th Century B.C., Aristotle marveled at the nimble gecko's ability to "run up and down a tree in any way, even with the head downwards."

There was an overall decrease in influenza vaccine uptake among U.S. adults from 2020 to 2024, according to a study published online in PLOS Global Public Health.

The world is facing an interconnected health crisis: zoonoses, antimicrobial resistance, environmental degradation, and climate change threaten millions of lives. An international expert group, The Lancet One Health Commission, warns in its first report of severe consequences if governments, business, and international organizations fail to change course immediately.

The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, they have discovered a five-protein panel present in APOE ε4 carriers across Alzheimer's disease, Parkinson's disease, frontotemporal dementia and amyotrophic lateral sclerosis.

Hypertensive disorders in pregnancy (HDP)—like chronic or gestational hypertension, preeclampsia, and eclampsia—are among the leading causes of maternal and infant death in the United States.

A 3D paper-based analytical device (3D-osPAD) with in situ gold signal amplification enables one-step, highly sensitive detection of anti-IFN-γ autoantibodies within 10 minutes, showing 10-fold improved sensitivity and high clinical accuracy for adult-onset immunodeficiency.

Lift a toast to summer fun but don't let risky drinking ruin the party.

The U.S. Centers for Disease Control and Prevention and the U.S. Food and Drug Administration, along with public health officials in several states, are investigating a multistate Salmonella outbreak linked to recalled frozen sprouted beans.

What if we could prevent people from developing obesity? The World Obesity Federation expects more than half the global population to develop overweight or obesity by 2035. However, treatment strategies such as lifestyle change, surgery and medications are not universally available or effective.

A child's death from measles has sparked urgent calls from British public health officials to get children vaccinated, as the UK faces an onslaught of misinformation on social media, much of it from the United States.

Tracking race-specific rates of cancer incidence and mortality is important for identifying racial differences in these outcomes and for monitoring efforts aimed at achieving the highest level of health for all.

Transitioning from diapers to the toilet is a major step for young children—and their parents.