Thousands of kids in mental health crisis are stuck for days in hospital emergency rooms, study finds

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut's immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators. The findings suggest that targeting these neurons and the molecules they produce could open the door to new treatments for inflammatory bowel disease and other disorders driven by gut inflammation.

University of Manchester scientists have mapped the mutations in the tiny protein chains that cause a subtype of muscular dystrophy. Published in the journal Nature Communications, the study provides a major insight into the muscular dystrophy subtype known collectively as Collagen VI-related dystrophy—or COL6-RD for short.

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

Hospitals, clinics, universities and other health-focused organizations routinely collect data on everything from spinal scans to sleep study results—but much of that valuable intelligence stays tucked away in-house.

A fading sense of smell can be one of the earliest signs of Alzheimer's disease even before cognitive impairments manifest. Research by scientists at DZNE and Ludwig-Maximilians-Universität München (LMU) sheds new light on this phenomenon, pointing to a significant role for the brain's immune response, which seems to fatally attack neuronal fibers crucial for the perception of odors.

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

New research from the Charles Perkins Center at the University of Sydney has uncovered a new biological pathway that may help explain why people with type 2 diabetes are more prone to developing dangerous blood clots, potentially paving the way for future treatments that reduce their cardiovascular risk.

Researchers at Columbia Engineering have built a cancer therapy that makes bacteria and viruses work as a team. In a study published in Nature Biomedical Engineering, the Synthetic Biological Systems Lab shows how their system hides a virus inside a tumor-seeking bacterium, smuggles it past the immune system, and unleashes it inside cancerous tumors.

Hospital Clínico San Carlos in Madrid-led research reports that intermittent theta-burst transcranial magnetic stimulation (TMS) paired with language therapy over six months was associated with positive outcomes in primary progressive aphasia (PPA). Improvements included less decline in regional brain metabolism and improvements in language abilities, functional independence, and neuropsychiatric symptoms.

A new study from Karolinska Institutet, published in Cell Reports Medicine, shows that follicular lymphoma (FL), a common type of blood cancer, is not one single disease but consists of three genetically distinct subtypes. The findings may help doctors diagnose and treat patients more accurately in the future.

Marijuana has been a hot topic for years, but one often clouded by misperceptions. Many turn to it as a perceived panacea, hoping it will address health issues or enhance their well-being if other options have fallen short. But what scientists are learning about weed's health effects might come as a surprise.

Laboratory mice are often considered the scientific equivalent of identical twins—genetically identical and expected to look and behave the same. But new research from the Faculty of Science, Charles University, shows that this assumption doesn't always hold true. The team discovered that the composition of the gut microbiota can dramatically influence the structure and function of the immune system—even in genetically identical animals.

People who regularly consume caffeine are usually in a better mood after a cup of coffee or another caffeinated drink—an effect that is much more pronounced in the morning than later in the day. This finding comes from a new study by researchers at Bielefeld University and the University of Warwick, published in the journal Scientific Reports. Participants reported feeling significantly happier and more enthusiastic on those mornings compared with other days at the same hour when they had not yet had coffee.

A new study has revealed that work-family conflict (WFC) is a common contributor to psychological distress among farmers in Ireland, with researchers calling for enhanced mental health support for farming families.

Going home from the hospital can be an anxious time for older people, their caregivers and family members. Yet limited resources exist to support culturally diverse caregivers to cope with this transition, despite Australia's multicultural society.

New research from SAHMRI has found no evidence that common chemical exposures during pregnancy shorten gestation or increase the risk of preterm birth in Australian women, contrasting with multiple previous international studies.

The results are in from Australia's most important test of the summer—and it wasn't just on the pitch. A national heart health screening initiative launched in memory of cricket legend Shane Warne has found nearly 7 in 10 Australians checked have at least one uncontrolled risk factor for cardiovascular disease.

The Centers for Medicare & Medicaid Services (CMS) is recommending a 2.5% "efficiency adjustment" payment reduction in the proposed 2026 Medicare Physician Fee Schedule based on the assumption that surgeons are faster today in completing procedures than they were five years ago. However, a new research letter published in the Journal of the American College of Surgeons shows that overall operative length and complexity have actually increased since 2019.