Tirzepatide reduces food intake and appetite, and affects brain functioning, more than placebo and liraglutide

It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps stabilize neurons, but in Alzheimer's disease, it begins to misfold and tangle inside neurons. It spreads across the brain forming toxic clumps that impair neuronal function and ultimately lead to cell death.

Recent research introduces a soft, injectable material designed for use in the eye to help protect and support damaged retinal tissue. It offers a gentle, biocompatible way to stabilize the inner eye environment and may assist future treatments like cell therapy and drug release.

An artificial intelligence (AI) model developed by Mayo Clinic and Ultromics, Ltd., an AI echocardiography company based in Oxford, England, is highly accurate in screening for cardiac amyloidosis, a rare and progressive type of heart failure, according to a new study. The model is the first and only AI tool of its kind.

We're constantly told to "eat healthy"—but what does that actually mean? Even doctors sometimes struggle to offer clear, practical advice on which specific foods support health, why they work and what real benefits people can expect.

For years, people living with obesity have been given the same basic advice: eat less, move more. But while this mantra may sound simple, it's not only ineffective for many, it can be deeply misleading and damaging.

As psychiatrists practicing within medical schools, we provide care not only for general patients but also for medical students struggling with emotional distress. Most aspects of medical school—academic, clinical, and personal (or more accurately, the absence of personal life)—are undeniably stressful. Yet despite being exposed to similar pressures, only a subset of students goes on to develop significant mental health issues. Why?

A new study from CUNY SPH researchers puts forth a straightforward way to measure whether hospitals are providing fair access to care for low-income and uninsured patients.

Cedars-Sinai investigators led an update of staging guidelines for HPV-positive throat cancer—now more common in the U.S. than cervical cancer, according to the American Cancer Society—that will make treatment of early-stage disease more consistent and appropriate. Their study was published in The Lancet Oncology.

Older people with diabetes who do not keep blood sugar levels low are three times more likely to develop eye disease compared to counterparts who have reduced blood sugar levels, suggests a new study by a UCL team.

Barbie's latest look includes a polka-dot crop top, chunky heels—and an insulin pump.

Researchers at University of Tsukuba have identified multiple T-cell subtypes with unique characteristics in follicular lymphoma, a prevalent type of blood cancer. These T cells regulate the proliferation and apoptosis of tumor cells and significantly affect patient prognosis. This discovery, published in Cancer Cell, is anticipated to enhance the understanding of malignant lymphoma and improve clinical management strategies.

The value of a recent biochemical discovery can be seen in the case of an 8-year-old boy who was playing typical sports in August 2023, but by November needed a wheelchair because of a rare disease that caused worsening paralysis.

Attention deficit disorder, with or without hyperactivity (ADHD), can be a problem outside of school because it disrupts the quality of life of families. Between stigmatization, chronic stress and feelings of helplessness, many families feel overwhelmed by this still poorly understood disorder.

A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.

The largest review of "gold standard" antidepressant withdrawal studies to date has identified the type and incidence of symptoms experienced by people discontinuing antidepressants, finding most people do not experience severe withdrawal.

Researchers from the University of Georgia found a new drug that may boost the brain's ability to heal itself after injury. The discovery could lead to significant advances in treating traumatic brain injuries, or TBIs.

A study published in iScience suggests that the magic of live performance art may be reflected in our brains. When people watched a live contemporary dance performance, their brainwaves synced up, signaling shared focus and attention—but that synchrony didn't occur when people watched the same performance alone on video.

Scientists have produced the first detailed characterization of the changes that weight loss causes in human fat tissue by analyzing hundreds of thousands of cells. They found a range of positive effects, including clearing out of damaged, aging cells, and increased metabolism of harmful fats.