Trial results show belzutifan shrinks rare neuroendocrine tumors and improves symptoms in patients

Every year, thousands of families sit in hospital rooms hearing words no one wants to hear: "We have done everything we can." What happens next, whether doctors stay engaged or step away, can transform one of life's most difficult moments for patients and their families.

Well after the United States government declared the pandemic emergency over, COVID-19 continued to cause about the same number of monthly work absences year-round as occurred during peak influenza months, a team that includes Yale School of Public Health (YSPH) researchers has found.

Body mass index (BMI) alone may not be enough to measure someone's risk of cardiometabolic disease, according to researchers at UTHealth Houston.

Pulmonary arterial hypertension (PAH) is a rare condition that's difficult to treat. The hallmarks of the disease—narrowing of the arterioles and capillaries that deliver blood to the lungs—force the heart to work harder. In severe cases, PAH can lead to heart failure.

After being treated with an electronic eye implant paired with augmented-reality glasses, people with sight loss have recovered reading vision, reports a trial involving a UCL (University College London) and Moorfields Eye Hospital clinical researcher.

A wireless retinal implant can restore central vision in patients with advanced age-related macular degeneration (AMD), according to clinical trial results published in the New England Journal of Medicine.

Grid cells are a class of specialized neurons in a brain region called the entorhinal cortex, which is known to support spatial navigation and some memory processes. Past neuroscience studies have found that as humans and other animals move in their surroundings, these cells fire following a grid-like pattern, creating a sort of internal map of the environment.

Around nine in 10 U.S. adults have not heard of cardiovascular-kidney-metabolic (CKM) syndrome, a newly defined health condition affecting nearly 90% of adults that includes heart disease, kidney disease, diabetes and obesity, according to a new survey from the American Heart Association, a relentless force changing the future of health for everyone everywhere. However, many are interested in learning more about it.

Patients with an aggressive form of breast cancer who are not candidates for immune checkpoint inhibitor therapy showed significantly improved progression-free survival when treated with the antibody drug conjugate sacituzumab govitecan compared to standard chemotherapy.

Results from a trial led by researchers from The University of Texas MD Anderson Cancer Center showed that a targeted therapy combination improved outcomes for patients with metastatic clear-cell renal carcinoma (ccRCC)—a type of kidney cancer—whose disease progressed following immunotherapy.

Overcrowding in hospital emergency departments (EDs) is bad for patients and expensive for the public purse.

Every year, more than 12,000 Australians undergo open heart surgery—an hours-long medical procedure during which surgeons go inside the chest cavity and repair faulty heart valves or bypass blocked cardiac arteries.

As the U.S. confronts a historic health care workforce crisis, a new white paper released today calls on federal and state policymakers to modernize outdated laws, regulations, and payment systems in order to harness the full potential of artificial intelligence (AI) in care delivery.

How do mammals manage to eat in situations that cause anxiety, step into exposed spaces, or slow down when anxiety drives them to keep moving? A new study pinpoints a leptin-sensitive circuit in the lateral hypothalamus that helps to overcome anxiety to perform essential behaviors such as exploring, feeding, and limiting maladaptive hyperactivity.

The American Gastroenterological Association (AGA) today released a new clinical practice guideline on the surveillance of Barrett's esophagus, the only known precursor to esophageal cancer (adenocarcinoma), a highly lethal cancer whose incidence has risen substantially over recent decades. The guideline provides eight evidence-based recommendations and several key implementation statements to help clinicians monitor patients after a diagnosis of Barrett's esophagus, a condition associated with chronic gastroesophageal reflux disease (GERD).

Melbourne researchers have discovered gender-affirming hormone therapy can alter body proteins to match a person's gender identity, potentially affecting susceptibility to certain health conditions.

Acute myeloid leukemia (AML), an aggressive and often fatal blood cancer, has long resisted a class of drugs called proteasome inhibitors, which work well in multiple myeloma.

A USC-led team has developed an innovative way to predict blood pressure outcomes after bariatric surgery that outperforms the current standard practice. In 108 adolescents who underwent bariatric surgery, the researchers used blood tests taken before the procedure to predict which patients would have improved blood pressure five years later. The study is one of the first to use cutting-edge "omics" techniques, which analyze the body's small molecules and proteins, to predict long-term health outcomes.