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Tumor cells can exploit damaged tissue in the pancreas to create new environments for growth

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  • 2025-09-26 21:28 event
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Tumor cells can exploit damaged tissue in the pancreas to create new environments for growth
Pancreatic cancer is an aggressive disease, and unlike many other cancers, survival rates have barely improved. Researchers at Karolinska Institutet, in collaboration with the Department of Pathology at Karolinska University Hospital, have now shown that pancreatic tumor cells not only spread in the connective tissue–rich environment that is a well-known characteristic of pancreatic cancer but also grow into damaged parts of normal pancreatic tissue. There, the cancer can create its own environment.

18. Isolated REM sleep behavior disorder may predict Parkinson's disease and dementia

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An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

19. Q&A: How do humans control their bodies, and what does it mean for Parkinson's disease risk?

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How humans move is an open question, according to Mark Latash, distinguished professor of kinesiology at Penn State.

20. Lifetime of social ties adds up to healthy aging at molecular level

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The cumulative effect of social advantages across a lifetime—from parental warmth in childhood to friendship, community engagement and religious support in adulthood—may slow the biological processes of aging itself. These social advantages appear to set back "epigenetic clocks" such that a person's biological age, as measured by analyzing DNA methylation patterns, is younger than their chronological age.

21. How a single protein rewires leukemia cells to fuel their growth

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Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead. Now, researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a single protein, IGF2BP3, that links these two processes together in leukemia cells. The protein shifts how cells break down sugar, favoring a fast but inefficient energy pathway, while also altering RNA modifications that help produce the proteins leukemia cells need to survive and multiply.

22. Safety-net hospitals carry the highest cost of gun injuries, analysis finds

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The initial hospital treatment of firearm injuries cost the U.S. health care system an estimated $7.7 billion between 2016 and 2021, with the largest share falling on urban trauma center hospitals that serve the highest proportion of Medicaid patients, reports a new study led by Northwestern Medicine.

23. Children with chronic conditions may face higher risk of food insecurity, study suggests

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Food insecurity is more common among children with a chronic medical condition than those without one, a new study suggests.

24. Telestroke patients may be more likely to receive treatment—but with greater delays

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Stroke patients evaluated using telemedicine (telestroke) have higher odds of receiving essential treatment, yet it takes them significantly longer to be treated—potentially limiting the benefits, a Michigan Medicine-led study finds.

25. In-home gun homicides of children has more than doubled since 2010: Study

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Nearly one-quarter of child and adolescent victims of firearm homicide were killed in their own homes from 2020-2021, including nearly two-thirds of child victims aged 12 and under, UCLA-led research finds.

26. Scientists launch world's most comprehensive human virus protein database

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Harnessing the power of AI, a research team at the MRC-University of Glasgow Center for Virus Research has launched Viro3D—the most comprehensive database of human and animal virus protein structure predictions in the world.

27. Tumor cells can exploit damaged tissue in the pancreas to create new environments for growth

  • 3 hours ago schedule
  • medicalxpress.com language

Pancreatic cancer is an aggressive disease, and unlike many other cancers, survival rates have barely improved. Researchers at Karolinska Institutet, in collaboration with the Department of Pathology at Karolinska University Hospital, have now shown that pancreatic tumor cells not only spread in the connective tissue–rich environment that is a well-known characteristic of pancreatic cancer but also grow into damaged parts of normal pancreatic tissue. There, the cancer can create its own environment.

28. Mediterranean diet leads to 75% symptom reduction in patients with mild to moderate psoriasis

  • 4 hours ago schedule
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Over 60 million people worldwide are affected by psoriasis, a chronic inflammatory skin disorder that causes red, scaly patches and persistent itching. A new study has found that following a Mediterranean diet—rich in plant-based foods, extra-virgin olive oil, and a moderate amount of fish, and poultry—could provide relief to psoriasis symptoms.

29. Open science yields broad-spectrum coronavirus antiviral

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A new broad-spectrum coronavirus antiviral, ASAP-0017445, has been nominated as a pre-clinical drug candidate by the Drugs for Neglected Diseases initiative (DNDi).

30. Growing evidence that the heart has a strong influence on thinking and feeling

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The influence of the heart and circulatory system occurs within milliseconds, and every single heartbeat plays a role. The role of the heart in the psyche and cognition is evident in the high coincidence of cardiovascular diseases, such as high blood pressure and heart attack, and mental illnesses, such as depression and anxiety disorders.

31. What research really says about autism

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About two to three percent of all Americans—including adults and children—are autistic. With recent reports that autism rates are rising, potentially due to improved diagnosis, there's a lot of conflicting information about the condition.

32. People who use drugs are trying to stay safe in a politicized world, our surveys show

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People who use drugs are increasingly trying to reduce harm—by obtaining the life-saving drug naloxone and testing their drugs—according to new data.

33. Back pain tied to higher rates of common diseases

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Back pain isn't just a debilitating condition; it may be a flag for other major health issues. New research shows the incidence of conditions such as heart disease, arthritis, diabetes and cancer is higher in people with back pain than in those without back pain.

34. Origins of the 'Ostrich Effect': Researchers pinpoint the age we start avoiding information—even when it's helpful

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In a world of information overload, it can feel soothing to stick your head in the sand.

35. Weight loss treatments for people with diabetes and obesity could lower the risk of obesity-related cancers

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Weight loss treatments, including medication and surgical procedures, may help lower the risk of obesity-related cancers in people with obesity and type 2 diabetes, a new study shows.

36. Patient advocate program reduces repeat ER visits

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A program that helps patients navigate the health care system with help from patient advocates significantly reduces repeat emergency department (ED) visits for low-acuity medical issues (minor or non-urgent needs), according to a study by University of Chicago Medicine researchers.

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