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Two distinct microglia populations linked to autism-like and depression-like behaviors in mice

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  • 2025-08-29 18:20 event
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Two distinct microglia populations linked to autism-like and depression-like behaviors in mice
The anterior insular cortex (aIC) is an important brain region known to contribute to the regulation of emotions, the integration of bodily sensations, decision-making and some other functions. Past studies have linked this brain region to some neuropsychiatric disorders characterized by unusual patterns of thinking and behavior, including autism spectrum disorder (ASD) and depression.

1.342. New guidelines for myocarditis and pericarditis aim to improve diagnosis and treatment

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New ESC Guidelines to improve the diagnosis and care of patients with myocarditis and pericarditis have been published at ESC Congress 2025 and also appear in the European Heart Journal.

1.343. Data analysis reveals 1 in 12 patients with multiple cancers carries inherited genetic risk

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A new study reveals that about one in 12 patients who are diagnosed with two or more different types of cancer were born with a mutation in a known cancer risk gene. This discovery could reshape how genetic testing is offered to cancer patients.

1.344. Increasing potassium levels can improve outcomes in patients at high risk of ventricular arrhythmia

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Targeting high-normal potassium levels reduced the risk of arrhythmias, hospitalization for heart failure or arrhythmia and death compared with no intervention, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.

1.345. Study in mice reveals a link between maternal stress during pregnancy and childhood eczema

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Maternal stress during pregnancy may be partly to blame for childhood eczema, according to a study on mice published in the journal Nature.

1.346. Study finds post-stroke aerobic exercise is safe and can help preserve cognition

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Stroke survivors at increased risk of developing dementia do not have therapies to reduce that risk, but new Monash University-led research could help change that.

1.347. Q&A: Expert says vaccine approval changes create economic challenge for health industry

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The Food and Drug Administration's COVID-19 vaccine approval issued Aug. 27 comes with restrictions on who's eligible to receive the vaccine. Meanwhile, the administration has endorsed seasonal influenza vaccines—but only if they do not include the mercury-based preservative thimerosal.

1.348. There are pros and cons for weight loss medications like Ozempic

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"Ozempic face." Five years ago, if you'd heard those words you would probably think it referred to an alien species.

1.349. Study highlights insufficient GP health checks for children on antipsychotics

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Australian GPs are not adequately monitoring for adverse health outcomes in children and adolescents who are prescribed antipsychotic drugs, according to a new study by University of Adelaide researchers.

1.350. The profound yet hidden effects of neglect on white matter structures in the brains of children

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When we think of child abuse, physical violence or emotional cruelty often comes to mind first. However, the most common form of maltreatment is actually much quieter: neglect.

1.351. Two distinct microglia populations linked to autism-like and depression-like behaviors in mice

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The anterior insular cortex (aIC) is an important brain region known to contribute to the regulation of emotions, the integration of bodily sensations, decision-making and some other functions. Past studies have linked this brain region to some neuropsychiatric disorders characterized by unusual patterns of thinking and behavior, including autism spectrum disorder (ASD) and depression.

1.352. Researchers create AI tool to help identify dangerous respiratory syndrome

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Researchers at Endeavor Health and Northwestern University have created an artificial intelligence-based tool to help doctors recognize an underdiagnosed, often fatal respiratory syndrome found in critically ill hospital patients. The tool has already identified historical cases with 93% accuracy, and it will soon be piloted for patients in treatment at Endeavor.

1.353. Hospital receives 300 backpacks designed to help kids get leukemia treatment on the go

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With colorful heart, bow, and flower patterns, the backpacks designed by a Philadelphia cancer philanthropy look from the outside just like the dozens of others filling store shelves as a new school year approaches.

1.354. HHS, Department of Education call for integration of nutrition education in medical schools

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The U.S. Department of Health and Human Services and Department of Education have announced an initiative urging medical schools to integrate nutrition education and training.

1.355. Kentucky Republican proposes studying psychedelic drug ibogaine to curb addiction

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A Kentucky lawmaker wants to revisit a previously abandoned idea for the state to fund research of an illegal psychedelic drug for its potential to treat drug addiction.

1.356. More nonsmokers are getting lung cancer: Oncologist explains why

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The demographics of lung cancer change every day. The disease, which directly affects the respiratory system, has long been associated with smokers—but that is rapidly changing.

1.357. Understanding help-seeking behaviors for premenstrual symptoms

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Premenstrual symptoms affect millions of people across the UK—yet nearly half never seek professional help, according to Cambridge researchers.

1.358. Study uncovers key proteins that keep the heart beating properly

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A groundbreaking new study led by researchers at the Masonic Medical Research Institute (MMRI) has identified that two closely related proteins, RBPMS and RBPMS2, act in tandem to protect the heart's ability to process the genetic information needed for normal heart development and function.

1.359. Q&A: As RFK Jr. moves toward radically simplified nutritional guidelines, a scientist looks back at their history

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With Robert F. Kennedy, Jr.'s appointment as Secretary of Health and Human Services under the second Trump administration, a new "Make America Healthy Again" (MAHA) agenda proposes to radically simplify nutritional guidelines, with news outlets reporting since the spring that a new guideline may be four pages long (as opposed to over 160) and stress that Americans should "eat whole food."

1.360. Departures roil the CDC leadership. What's next for the agency?

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The firing of the director of the U.S. Centers for Disease Control and Prevention and the resignation of several high-profile agency leaders pose immediate challenges to the operations of the nation's premiere public health agency, experts said.

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