US health experts reassess hormone replacement therapy risks

Guoping Li, Ph.D., of the Department of Anesthesia, Critical Care & Pain Medicine at Massachusetts General Hospital, is the lead author, and Saumya Das, MD, Ph.D., of the Cardiovascular Research Center at Massachusetts General Hospital, is the senior author of a paper published in Science, titled "A hypoxia-responsive tRNA-derived small RNA confers renal protection via RNA autophagy."

While parenthood is linked with better mental health, new UCL research reveals social and economic circumstances also matter.

New research from Huntsman Cancer Institute at the University of Utah published in Surgical Clinics of North America shows that some people are more likely to face delays and worse outcomes from dangerous types of skin cancer. These groups include older adults, people living in rural areas, and those who have trouble getting regular medical care.

On the eve of the Lionesses' squad for the UEFA Women's Euros 2025 being announced, Millie Bright announced that she was unavailable for selection. She had been a pivotal part of the team that won the competition three years ago and captained the squad in the 2023 FIFA Women's World Cup.

Thomas McElrath, MD, Ph.D., of the Department of Obstetrics & Gynecology at Brigham & Women's Hospital, is the lead and corresponding author of a paper published in JAMA Network Open, "Utility of the US Preventive Services Task Force for Preeclampsia Risk Assessment and Aspirin Prophylaxis."

A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being.

An additional ultrasound measurement to assess resistance in fetal blood vessels can improve the decision of whether to expedite birth when a woman in the final stage of pregnancy perceives less fetal movements, according to a study published online July 10 in The Lancet Obstetrics, Gynaecology, & Women's Health.

Anti-bullying laws (ABLs) are highly effective in reducing suicidal behaviors among overweight and obese high school students in the U.S., according to a new study co-authored by a University of Massachusetts Amherst doctoral student.

US health authorities are set Thursday to reassess hormone replacement therapy (HRT), a treatment used by menopausal women around the world but long clouded by debate over its risks.

US Food and Drug Administration Commissioner Marty Makary signaled Thursday that he is open to revising strict warning labels on hormone replacement therapy, following testimony from experts who said the treatment's risks have long been exaggerated.

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine. The findings suggest the possibility of future therapies that would block or reduce such changes to treat or prevent age-related chronic liver diseases—effectively making the liver more youthful and resilient.

Acute lymphocytic leukemia is one of the most commonly diagnosed cancers in children, although it is rare. It begins in the bone marrow and rapidly progresses.

A new study by a Tulane University researcher casts doubt on a widely used shortcut in rectal cancer drug trials, raising concerns that some treatments may be fast-tracked for approval without evidence they help patients live longer.

The mystery of how cancers build up resistance mechanisms and evade the treatments that should have destroyed them is a hugely pressing question. Overcoming cancer treatment resistance—a phenomenon that contributes to as much as 90% of cancer-related deaths—is among the top missions of 21st century medical research.

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the lungs are injured according to researchers from Weill Cornell Medicine. Injury—whether by infection, toxins, or trauma—can cause fluid buildup in the lungs, making it hard to breathe. In response, the body's lymphatic system, a network of vessels, tissues and organs, ramps up to clear inflammation. Excess fluid called lymph is removed from the body's tissues and returned to the blood for disposal. But the underlying mechanism of this process was unknown.

Breastfeeding is often linked with better health for both mothers and babies, but it does not protect all women against breast cancer. The reason remains unknown. Since breast cancer in young women is on the rise, understanding why breastfeeding is protective in some women but not others is critical.

Researchers at The Hong Kong University of Science and Technology (HKUST) have developed a groundbreaking AI technology that reconstructs precise 3D bones and organs models from minimal X-ray images, slashing patients' radiation exposure by up to 99% compared to CT scans.

A new study led by Indiana University School of Medicine researchers revealed a potential strategy to address neurobehavioral challenges associated with neurofibromatosis type 1, or NF1, a genetic disease that primarily affects the skin and nervous system. The findings, recently published in the Journal of Clinical Investigation, may also have implications for treating hundreds of other rare genetic diseases.