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Vaccines trigger rapid lymph node responses, researchers discover

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  • 2025-08-19 01:21 event
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Vaccines trigger rapid lymph node responses, researchers discover
Lymph nodes are a key part of the human immune system, whose primary function is to combat infections. The effectiveness of vaccines is based on their ability to trigger events in lymph nodes that lead to the development of an immune response that protects the host against pathogens.

19. Survey reveals more than 40% of family caregivers in Hong Kong have mental health issues

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Globally, rapidly aging populations give rise to increasing demand for home care services. The World Health Organization estimates that approximately 1.3 billion people worldwide require care due to aging or disability. In Hong Kong, due to rising health care costs and deeply rooted cultural norms that emphasize family bonding, caregiving is often performed by family members, which imposes heavy physical and mental strain.

20. MIGHT: Powerful new algorithm advances reliability of AI with applications in medical diagnostics

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Two studies led by Johns Hopkins Kimmel Cancer Center, Ludwig Center, and Johns Hopkins Whiting School of Engineering researchers report on a powerful new method that significantly improves the reliability and accuracy of artificial intelligence (AI) for many applications. As an example, they apply the new method to early cancer detection from blood samples, known as liquid biopsy.

21. Promising new combo therapy found for drug-resistant melanoma

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A new study from Moffitt Cancer Center may offer a breakthrough for patients with advanced melanoma who don't respond to current immunotherapy treatments. The research, published in the Journal for ImmunoTherapy of Cancer, found that adding a third immune-targeting drug to existing therapies helped shrink tumors in lab models of treatment-resistant melanoma.

22. An alphabet for hand actions in the human brain

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Using a corkscrew, writing a letter with a pen or unlocking a door by turning a key are actions that seem simple but actually require a complex orchestration of precise movements. So, how does the brain do it?

23. Untangling glucose traffic jams in type 2 diabetes

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Just as smart traffic management ensures smooth vehicular movement during peak hours, our body relies on a molecular traffic system to manage the surge in glucose levels after a meal. Pancreatic β-cells play a major role in this system by taking up glucose from the blood and triggering insulin release into the bloodstream. Inside these cells, glucose uptake is managed by glucose transporters (GLUTs)—proteins that move to the β-cell surface when blood glucose levels rise and facilitate the entry of glucose into the cell to kickstart insulin release.

24. Understanding how cells in small intestine of patients with celiac disease communicate with one another

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A new comprehensive atlas of cells fills gaps in knowledge on how different cells in the intestine act together to drive celiac disease, potentially opening new avenues for future therapeutic intervention.

25. Hundreds may have been exposed to rabies in Wyoming park cabins

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Hundreds of people may have been exposed to rabies after staying in cabins infested with bats at Wyoming's Grand Teton National Park.

26. Cognitive impairment, work productivity loss linked in bipolar disorder

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There is a weak correlation between change in cognitive impairment and change in work productivity loss in adults with bipolar disorder, according to a study published online Aug. 4 in the Neuropsychopharmacology Reports.

27. Texas declares measles outbreak over

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The Texas measles outbreak that sickened 762 people since late January is over, state health officials said Monday.

28. Vaccines trigger rapid lymph node responses, researchers discover

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Lymph nodes are a key part of the human immune system, whose primary function is to combat infections. The effectiveness of vaccines is based on their ability to trigger events in lymph nodes that lead to the development of an immune response that protects the host against pathogens.

29. Wireless sweat patch could offer new way to monitor cystic fibrosis at home

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A new wireless and wearable device developed by Northwestern Medicine scientists, in collaboration with Northwestern University spinout company, Epicore Biosystems, measures specific biomarkers in a person's sweat with similar accuracy to standard testing methods and has the potential to improve clinical decision-making for cystic fibrosis, as detailed in a recent study published in the Proceedings of the National Academy of Sciences.

30. Community-based approach boosts family engagement in ADHD care

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Innovative intervention delivered by trained community health workers—meaning nonclinical personnel with deep knowledge of the community—increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders. This intervention for parents and caregivers, covering topics that range from education about ADHD to discussions of stigma and barriers to care, intends to reduce inequities in access to evidence-based treatment and boost family engagement in ADHD care.

31. New guidance released to improve safety and outcomes of patent ductus arteriosus closure in premature infants

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The Society for Cardiovascular Angiography & Interventions (SCAI) has published a new position statement that provides best-practice guidance for the treatment of patent ductus arteriosus (PDA) using transcatheter occlusion (tcPDA) in premature infants.

32. Self-powered patch monitors biomarkers without drawing blood

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Researchers have developed a self-powered microneedle patch to monitor a range of health biomarkers without drawing blood or relying on batteries or external devices. In proof-of-concept testing with synthetic skin, the researchers demonstrated that the patches could collect biomarker samples over periods ranging from 15 minutes to 24 hours.

33. Identifying a compass in the human brain

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Zhengang Lu and Russell Epstein, from the University of Pennsylvania, led a study to explore how people maintain their sense of direction while navigating naturalistic, virtual reality cities.

34. Rethinking myeloma: Bone marrow map reveals hidden complexity of blood cancer

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Researchers have created the first detailed molecular map of the human bone marrow, revealing new insights that could reshape our thinking about how an incurable blood cancer grows and spreads.

35. GLP-1 drugs linked to reduced symptoms in chronic skin condition hidradenitis suppurativa

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A multicenter French study led by Rennes University Hospital reports potential benefits of glucagon-like peptide-1 receptor agonists for hidradenitis suppurativa (HS), with statistically significant reductions in HS-related scores at six months and at last follow-up.

36. How AI support can go wrong in safety-critical settings

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When it comes to adopting artificial intelligence in high-stakes settings like hospitals and airplanes, good AI performance and brief worker training on the technology is not sufficient to ensure systems will run smoothly and patients and passengers will be safe, a new study suggests.

37. Game changer: How data science is revolutionizing athlete performance

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Sports coaches have always made decisions based on experience, observation and intuition. But they are increasingly relying on hard evidence. Behind the scenes, a quiet revolution is transforming sport—driven not by human skills but by data.

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