Vision-saving eye surgery may also improve survival in patients with rare eye cancer, study finds

Maintaining weight loss with regular exercise rather than the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide, a drug used to treat type 2 diabetes and obesity, seems to reduce atherosclerosis development in adults with obesity—a leading underlying cause of cardiovascular disease.

GLP-1 receptor agonist drugs protect against diabetic retinopathy, a common complication of diabetes that can lead to sight loss, suggests new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15–19 September) and published in the journal Pharmaceutics.

New research has shown how harmful gambling is clearly linked to a marked and long-lasting increase in suicide attempts among young people in the UK.

A key federal vaccine advisory panel whose members were recently replaced by Health and Human Services Secretary Robert F. Kennedy Jr. is expected to vote to recommend delaying until age 4 the hepatitis B vaccine that's currently given to newborns, according to two former senior Centers for Disease Control and Prevention officials.

Researchers at Sutter's California Pacific Medical Center (CPMC) in San Francisco, Calif. have identified potential new therapeutic strategies for patients with advanced melanoma who no longer respond to immunotherapy—an aim representing one of the most pressing clinical challenges in cancer care today.

For a long time, physicians and scientists believed our lungs were sterile (germ-free). But modern science indicates otherwise. Now we know they contain allergens, bacteria or viruses we inhale, such as influenza or SARS-COV-2, the virus that causes COVID-19. When those contaminants combine with inflammation, it can lead to chronic lung disease.

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found that neurons known to help detect pain are also critical for reducing harmful lung inflammation that leads to the disease.

Stanford Medicine researchers have developed an artificial intelligence tool to help scientists better plan gene-editing experiments. The technology, CRISPR-GPT, acts as a gene-editing "copilot" supported by AI to help researchers—even those unfamiliar with gene editing—generate designs, analyze data and troubleshoot design flaws.

A drug called riluzole, commonly used to treat amyotrophic lateral sclerosis (ALS) and other motor neuron diseases, could also assist in recovery from spinal cord injuries, according to research from the University of Toronto's Temerty Faculty of Medicine.

Abbreviated, 15- to 30-minute medication visits have become common in psychiatry now that many insurers model their reimbursement patterns on internal medicine and surgery. To support practicing psychiatrists, a series of four columns in the Journal of Psychiatric Practice, describes how to feasibly combine brief psychotherapy with longitudinal pharmacotherapy. The final installment appears in the September issue.

Cardiac arrest happens when the heart stops pumping blood properly, cutting off oxygen to the brain and other vital organs. In these emergencies, cardiopulmonary resuscitation (CPR) can help keep blood and oxygen moving until medical help arrives. For children, CPR usually needs both chest compressions and rescue breaths, because many cases are caused by breathing problems such as drowning, choking, or serious illness.

Mayo Clinic researchers have developed a new way to predict whether existing drugs could be repurposed to treat heart failure, one of the world's most pressing health challenges. By combining advanced computer modeling with real-world patient data, the team has created "virtual clinical trials" that may facilitate the discovery of effective therapies while reducing the time, cost, and risk of failed studies.

It is estimated that one-third of the 50 million people worldwide with epilepsy are resistant to anti-seizure medications. These patients, with drug-resistant epilepsy, have limited treatment options beyond surgery to control their seizures. Even surgical interventions become difficult in many of these patients due to challenges in pinpointing the anatomical source of their seizures, such as the seizures originating from multiple regions of the brain.

Noonan syndrome with multiple lentigines (NSML) is a rare genetic disorder that causes short stature, distinctive facial features, and clusters of dark skin spots called lentigines. But its most serious impact is a dangerous thickening of the heart muscle, the onset of which is not well understood.

Alzheimer's disease (AD) is a neurodegenerative condition that typically affects older people and is the leading cause of dementia worldwide. AD is characterized by progressive cognitive impairment caused by a decades-long process that leads to neuronal dysfunction. The global prevalence of AD is projected to triple by 2050 and currently there are limited strategies to prevent or slow down the progression of this devastating condition.

Researchers have provided new insights into how exercise helps lose weight. They discovered a mechanism by which the compound Lac-Phe, which is produced during exercise, reduces appetite in mice, leading to weight loss. The findings appeared in Nature Metabolism.

In almost all solid tumors—i.e. cancers with a solid tissue structure—the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node involvement has a significant influence on the choice of treatment and the chances of survival for patients.

Nitazenes—a class of highly potent synthetic opioids—are rapidly emerging as a major contributor to the overdose crisis, according to a Pain Medicine review published today by authors from Vanderbilt University Medical Center and the University of Pittsburgh Medical Center.