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A combination of iza-bren (BL-B01D1), a novel bispecific antibody-drug conjugate (ADC), with osimertinib demonstrated a 100% objective response rate (ORR) in patients with first-line EGFR-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
An analysis from the Phase III CheckMate 77T trial confirms that perioperative nivolumab does not compromise health-related quality of life (HRQoL) in patients with resectable non-small cell lung cancer (NSCLC), including those with Stage III N2 disease.
Contaminated metal at an industrial site in Indonesia may be the source of radioactive material that led to massive recalls of imported frozen shrimp, international nuclear safety officials say, as efforts are underway to halt more U.S.-bound shipments.
It makes sense to approach some marketing efforts with skepticism. Scams, deepfakes, and deceptive social media posts are common, with people you don't know seeking to profit from your behavior.
The brain has its own waste disposal system—known as the glymphatic system—that's thought to be more active when we sleep.
Adding the novel medication baxdrostat to standard care may help manage high blood pressure and delay the progression of kidney disease in people with chronic kidney disease and uncontrolled high blood pressure , according to preliminary research presented at the American Heart Association's Hypertension Scientific Sessions 2025.
Researchers at the Weizmann Institute of Science traced a neural mechanism that explains why humans explore more aggressively when avoiding losses than when pursuing gains. Their work reveals how neuronal firing and noise in the amygdala shape exploratory decision-making.
In the depths of the ocean, marine corals have evolved intricate, porous structures that shelter diverse microbial communities.
Michelle Newmark has tried—and failed—a couple times to get an updated COVID-19 vaccine.
The World Health Organization recommended a range of blockbuster weight-loss drugs to treat diabetes and obesity globally for the first time on Friday, calling for cheap generic versions to be made available for people in developing countries.
Mpox no longer represents a global public health emergency, the WHO said Friday, following a steady decline in cases and deaths in the Democratic Republic of Congo and other affected countries.
The environment we grow up in plays a critical role in shaping our lifelong health. The exposome refers to the totality of environmental exposures from conception onward, including factors such as air pollution, nutrition, stress, and social context.
Suicide remains a leading cause of death among adolescents and young adults worldwide. However, recent global data reveal heterogeneous suicide trends across regions.
Artificial intelligence can detect and interpret social features between people from images and videos almost as reliably as humans, according to a new study from the University of Turku in Finland published in the journal Imaging Neuroscience.
In the quest to address infertility, Cornell researchers have developed a groundbreaking device that could simplify and automate oocyte cumulus removal, a critical step in assisted reproductive technologies.
System-based disparities in predialysis access to nephrology care contribute to disparities in the likelihood of having a mature, usable arteriovenous access for starting hemodialysis (incident vascular access) among Hispanic individuals, according to a study published online Sept. 5 in JAMA Network Open.
Only forty-two percent of youths with sickle cell disease (SCD) received dental services in 2022, according to a research letter published online Sept. 3 in JAMA Network Open.
Over 5% of children and adolescents are diagnosed with attention deficit/hyperactivity disorder (ADHD) globally. This condition is characterized by a short attention span, hyperactivity or impulsive behavior that is age-inappropriate, making it difficult for patients to navigate interpersonal relationships, the formal education system, and social life.
Late-onset Alzheimer's disease (LOAD) is the most common form of dementia, with symptoms appearing after age 65. Since carriers of clusterin risk alleles have an increased likelihood of developing LOAD, the associated clusterin protein is of interest to researchers. In order to better understand the function of the associated protein, researchers at the Max Planck Institute of Biochemistry have deciphered the molecular basis for the chaperone function of clusterin.