When a fear of closeness and vulnerability leads to destructive behavior

Researchers at the Jack, Joseph and Morton Mandel School of Applied Social Sciences at Case Western Reserve University have discovered a target in brain function that could change how schizophrenia patients are treated.

The first global standard that harmonizes what outcomes to measure in dengue treatment trials has been published Oct. 7 in The Lancet Infectious Diseases. Co-led by researchers at King's and the University of Oxford, this solves a longstanding discrepancy in terms of what is measured in these trials.

Scientists at Virginia Tech's Fralin Biomedical Research Institute at VTC and their collaborators are exploring emerging trends in cancer immunotherapy with back-to-back review articles published in Nature Cancer and Trends in Cancer that look at how nanotechnology could reprogram the immune system and help overcome tumors' defenses.

Every minute, a woman in the U.S. requires a blood transfusion due to heavy menstrual bleeding, or HMB. One in three women reports having the condition—which can lead to iron deficiency and anemia—and missing an average of 3.6 weeks of work a year, costing the U.S. economy roughly $94 billion annually, according to the nonprofit Wellcome Leap. Patients routinely suffer for up to five years before they get help, despite HMB being more common than asthma or diabetes in reproductive-aged women.

A research team at The University of Osaka, joined by Professor Shimon Sakaguchi—the latest Nobel Laureate in Physiology or Medicine—has identified a previously uncharacterized subset of immune cells called precursor T follicular regulatory cells (preTfr) that play a critical role in preventing autoantibody production.

Acute or short-lived pain, despite its bad reputation, is usually a lifesaver. It acts as a transient negative sensory experience that helps us avoid danger. Touch a hot stove, stub a toe, or bonk your head on a low branch, and the nervous system cues up an "Ow!" Over time, the sting fades, the wound heals, but the lesson sticks.

Newly identified brain cells evolved along the theme, "Life is uncertain; Eat dessert first." The neurons, located in the front part of the brain, are most active when the outcome of a decision is uncertain, suggesting that they help with decision making, along with learning and mental flexibility in general.

Errors in a gene known to cause a serious neurodevelopmental condition in infants are also linked to the development of Parkinson's disease in adolescence and adulthood, according to new research.

A preclinical study by biomedical scientists at the University of California, Riverside, has shown why some people with multiple sclerosis, or MS, also suffer from seizures—a debilitating complication that can worsen cognitive outcomes and accelerate disease progression.

IV hydration spas are popping up across the United States, offering pricey vitamin infusions that promise energy, detox or immune support, but experts warn the science doesn't back up those claims.

Halloween is all about costumes, candy and fun, but all that sugar can take a toll on your child's teeth.

An international project to create a "digital twin" of the human immune system could help scientists finally tackle grand challenges such as autoimmune disorders and infectious diseases.

Imagine two scenarios. In the first, you're hiking uphill on a warm day, beads of sweat rolling down your forehead. In the second, you've just remembered you have an exam tomorrow and now the palms of your hands are cold and damp.

Breastfeeding until at least six months helps babies to fight off infections and reduces chronic inflammation, according to a new study. And better understanding the way specific nutrients in breast milk impact the immune system will improve health outcomes for all infants, including those not breastfed.

Could an anomaly in the developing brain explain motor difficulties occurring decades later in people with rare movement disorders?

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide insights into the earliest steps of cancer development and the role of mutations in healthy tissue.

Harmful genetic changes in sperm become substantially more common as men age because some are actively favored during sperm production, new research has revealed.

A new study led by researchers at the Department of Population Medicine–Harvard Pilgrim Health Care Institute, Boston Medical Center, and Boston University School of Public Health finds that how Medicaid programs are designed can make a big difference in the care pregnant and postpartum people receive.