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Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer

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  • 2025-09-25 02:11 event
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Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer
Molecular profiling has transformed cancer care, but 30% of high-risk pediatric cancers do not have actionable therapeutic targets, limiting personalized treatment options and negatively affecting survival outcomes.

4. Most cancer patients are exposed to misinformation: Researchers pilot way to steer them to facts

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Ninety-three percent of patients with a new cancer diagnosis were exposed to at least one type of misinformation about cancer treatments, a UF Health Cancer Center study has found.

5. Only 36.4% of U.S. adults had no CVD risk factors in recent years

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From August 2021 to August 2023, only 36.4% of U.S. adults had no cardiovascular disease (CVD) risk factors, according to a September data brief published by the National Center for Health Statistics.

6. Dried blood spot test reliably detects congenital cytomegalovirus at birth, study finds

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New research from the University of Minnesota Medical School confirms that testing for congenital cytomegalovirus (cCMV) at birth using the routinely collected dried blood spot (DBS) is a reliable and effective method to identify newborns at risk for long-term developmental challenges. The findings are published in JAMA Network Open.

7. The power of touch: Skin-to-skin contact linked to preemie brain growth

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Preterm infants born before 32 weeks who received more skin-to-skin contact while in the hospital showed stronger brain development in areas tied to emotion and stress regulation than babies who received less skin-to-skin care, according to a study published in Neurology. The study does not prove that skin-to-skin care directly causes stronger brain development, it only shows an association.

8. Lung-on-a-chip with working immune system protects itself like a living organ

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Georgia Tech and Vanderbilt researchers have built the first lung-on-a-chip with a working immune system, a breakthrough with the potential to reshape how we study disease, move beyond animal testing, and administer lifesaving therapies. The work is published in the journal Nature Biomedical Engineering.

9. Sharp rise in memory and thinking problems among U.S. adults, study finds

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A growing number of U.S. adults—particularly those under 40—are reporting serious challenges with memory, concentration and decision-making, according to a new study published in Neurology.

10. Adherence to safe sleep practices declines during and after infant illness

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Reported adherence to safe sleep practices appears to be low among caregivers of infants presenting to the emergency department for low-acuity illness and worsens during and after illness, according to a study published online Sept. 18 in Pediatrics.

11. Sugary drinks linked to depression via the gut microbiome—especially in women

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A new study involving the German Center for Diabetes Research (DZD) provides strong evidence that sugary drinks affect not only metabolic health, but also mental health—especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.

12. Astrocytes emerge as the unexpected conductors of brain networks

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A collaborative French–Swiss study reveals a previously unknown role for astrocytes in the brain's information processing. Published in the journal Cell, the research shows that these glial cells are capable of integrating signals from several neurons at once—a conceptual shift in our understanding of the brain.

13. Zebrafish models offer fast, effective guidance for personalized therapies for kids with high-risk cancer

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Molecular profiling has transformed cancer care, but 30% of high-risk pediatric cancers do not have actionable therapeutic targets, limiting personalized treatment options and negatively affecting survival outcomes.

14. Artificial light weakens menstrual cycle's natural synchronization with lunar phases, study suggests

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There is no question that the moon has a significant influence on Earth. Its gravitational pull affects the planet and moves water masses in the daily rhythm of ebb and flow (tides)—this point is undisputed. More difficult to answer is the question of whether the same gravitational force also affects life on Earth, especially the human organism. The discussion becomes even more complicated when it comes to how the fluctuating brightness of the Earth's satellite between full and new moon affects humans.

15. Brazilian researchers warn that health care for transgender people is under threat

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Recent restrictions on public policies and health care for transgender people in several countries, including Brazil, threaten to dismantle existing care structures for this population and could lead to setbacks. This warning is contained in an article published in the scientific journal Nature Medicine by a group of Brazilian researchers.

16. In pregnant mice with severe flu, harmful molecules can breach fetal barriers

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A new study from the University of Illinois Urbana-Champaign shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain.

17. Gut microbiota and immune response linked to breast cancer risk

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Breast cancer remains one of the most common cancers worldwide and a leading cause of cancer-related deaths among women. Despite advances in screening and treatment, advanced stages of the disease remain difficult to manage, and researchers continue to search for better ways to understand and reduce risk.

18. Report explores perspectives on living with dementia

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To experience or even contemplate dementia raises some of the most profound questions: What does it mean to be a person? How does someone find meaning in life while facing progressive neurological deterioration? What do health care providers, or residents of a neighborhood, or citizens of aging societies, owe to people living with dementia, and why? And how do shared ideas and values – narratives – that circulate within societies and groups shape the experience of living with dementia, for better or worse?

19. Reducing cannabis-related risks becomes focus of new app

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Scientists at Université de Montréal's affiliated hospital research center (CRCHUM) are testing out a mobile application to help young adults who have a first episode of psychosis to support safer cannabis consumption.

20. Racial discrimination linked to higher risk of developing psychotic symptoms

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Being racially or ethnically discriminated against may increase the risk of later developing psychotic symptoms, finds a major review of international evidence led by University College London (UCL) researchers.

21. IQ appears to affect ability to listen in noisy settings

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You're in a bustling café with a friend. The din is making it hard to tune in to the conversation. The scenario might suggest you'd benefit from a hearing aid. On the other hand, new research suggests that speech-perception difficulty might relate to your cognitive ability.

22. Older adults can bounce back to thriving health, study finds

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A new Canadian study is offering a powerful message to older adults and those who care for them: it's never too late to bounce back. Researchers at the University of Toronto have found that nearly one in four older adults age 60 or older who reported poor well-being at the beginning of a national study—due to pain, health issues, low mood, or isolation—had regained optimal well-being within just three years.

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