A doctor sees new hope for Alzheimer's disease patients and families
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- 2025-07-24 17:50 event
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Brain-computer interfaces (BCIs)—implantable medical devices used to treat neurological conditions—are becoming increasingly sophisticated, making them more vulnerable to cyberattacks.
A research team has identified STAT1 as a key transcriptional regulator that enhances platelet production from induced pluripotent stem (iPS) cells by epigenetically controlling LIN28A and its downstream let-7-RALB axis. The study, published in Blood Advances, was led by Dr. Si Jing Chen (Chiba University) and Professor Koji Eto (Department of Clinical Application)
TherVacB, a therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. The first patient was enrolled in June 2025 and treated with the vaccine. In a previous trial in healthy volunteers, the vaccine demonstrated a favorable safety profile and triggered the desired immune responses.
In a recent paper published in Nature, researchers at the University of Chicago discovered how to block nicotinamide N-methyl transferase (NNMT), an enzyme that is involved in the progression of high-grade serous ovarian cancer. The team showed that NNMT promotes cancer growth by helping the tumor evade the immune system, and they also developed a potent NNMT inhibitor that could help overcome therapy resistance, providing a new and effective strategy for treating ovarian cancer.
Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.
The benefits of exercise and its positive influence on physical and mental health are well documented, but a new Yale and VA Connecticut study sheds light on the role genetics plays for physical activity, accounting for some of the differences between individuals and showing differences in biology for physical activity at leisure versus physical activity at work and at home.
Many clinicians remain unaware of the health risks linked to PFAS, short for perfluoroalkyl and polyfluoroalkyl substances, despite rising medical and public awareness of the chemicals and their toxicity. PFAS can affect nearly every organ system and linger in our bodies for decades, raising risks of cancer, immune deficiencies, and pregnancy complications.
About 90,000 people are diagnosed with Parkinson's disease (PD) each year—one person every six minutes. While most people associate PD with tremors and stiffness, the condition is far more complex than these symptoms and may affect more than just movement.
24 July 2025, Cairo, Egypt – On 17 July 2025, the World Health Organization (WHO) Regional Office for the Eastern Mediterranean launched the Regional Coalition for Mental Health and Substance Use Prevention. A webinar held for the launch brought together civil society organizations (CSOs) working on mental health and substance use from across the Region. Speakers from the Regional Office included Regional Director Dr Hanan Balkhy, Director of Programme Management Dr Adham Ismail, Regional Advisor Dr Khalid Saeed, and Technical Officer Dr Dalia Elasi. Other speakers included the Director of Partnerships and Secretariat Lead at the Global Mental Health Action Network (GMHAN) Dr Antonis Kousoulis, GMHAN Officer Ms Divya Sharma, President of Justice for Health Sasha Hajj-Assaf, and representatives from key member organizations. The Coalition aims to promote mental health literacy, prevent substance use and reduce stigma by meaningfully engaging and empowering people with lived experience (PWLE) and their organizations. It is hosted on an interactive platform in collaboration with GMHAN, led by United for Global Mental Health. The platform includes links to the websites of member organizations and a unique engagement space GMHAN Circle. The dedicated page Civil Society Speaks highlights success stories on programmes, initiatives and campaigns for mental health and substance use, implemented and shared by CSOs across the Region. The Coalition’s mandate aligns with the WHO’s Read more...
The combination of a recently approved blood test for detection of Alzheimer's disease combined with two medications that slow progression of the disease is drastically improving outcomes for patients and their families, according to a neurologist and surgeon at Yale New Haven Health.
A GOP-led Congress has approved $186 billion in cuts to the food assistance program through 2034. The second Trump administration has said that healthy eating is a priority.
Ancient bacteria that have evolved to become integral to our cells—converting nutrients from food into energy—may also contribute to neurologic disorders, such as spinal muscular atrophy (SMA) and autism, according to research in the lab of Yongchao Ma, Ph.D., from Ann & Robert H. Lurie Children's Hospital of Chicago.
Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological disability in the world.
A new study from the University of Colorado Anschutz Medical Campus shows that free, open-source artificial intelligence (AI) tools can help doctors report medical scans just as well as more expensive commercial systems, without putting patient privacy at risk.
In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut. Support cells known as telocytes use fine extensions—like neurons in the brain—to deliver signals directly to intestinal stem cells.
COVID-19 is rising in prevalence in many states nationally following the July 4 holiday week, but the role of the main therapy to treat it—the antiviral drug Paxlovid—is less clear.
Bipolar disorder is a mental health condition characterized by extreme mood swings, with alternating periods of depression and manic episodes. Past research suggests that bipolar disorder has a strong genetic component and is among the most heritable psychiatric disorders.
Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other medications. However, the brain mechanisms important for these rapid treatment effects are yet to be determined.
The Food and Drug Administration, making good on a Trump administration promise to examine the usage of antidepressants, on July 21 convened a panel largely of antidepressant skeptics to discuss the health impacts of taking such medicine while pregnant, though several panelists have no particular expertise on pregnancy research.