Inhibiting STAT1 boosts platelet production via LIN28A-let-7 control

A new study shows that while decentralized clinical trials (DCTs) are making research more accessible, they also bring challenges for research staff that can increase clinical staff workload, negatively impact the patient experience, and impact trial delivery.

We're constantly being reminded by news articles and social media posts that we should be getting more sleep. You probably don't need to hear it again—not sleeping enough is bad for your brain, heart and overall health, not to mention your skin and sex drive.

Most sports look to support their athletes to become "faster, higher, stronger"—in reference to the Olympic Games' original motto—so it is perhaps surprising that cycling's world governing body is trying to slow down elite riders.

A study published in Eurosurveillance has found evidence of substantial lifetime exposure to hepatitis B and C viruses in Ukraine in a 2021 nationwide, representative sample of the population, with findings also suggesting significant ongoing circulation of these viruses.

When actor Orlando Bloom revealed recently that he'd undergone a procedure to have his blood "cleaned," many people raised eyebrows. The "Pirates of the Caribbean" star had turned to a treatment known as apheresis—a medical process in which blood is removed from the body, centrifuged or filtered to extract certain components, then returned in an attempt to flush out microplastics and other toxins.

Two teenage boys were thrown from a jet ski during a ride on the Georges River in Sydney's south this week. One died at the scene. The other lost an arm, and was rushed to hospital in a serious condition.

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents—especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

Every time Ashton Alexander sees an ad for Georgia Pathways to Coverage, it feels like a "kick in the face."

Brain-computer interfaces (BCIs)—implantable medical devices used to treat neurological conditions—are becoming increasingly sophisticated, making them more vulnerable to cyberattacks.

TherVacB, a therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. The first patient was enrolled in June 2025 and treated with the vaccine. In a previous trial in healthy volunteers, the vaccine demonstrated a favorable safety profile and triggered the desired immune responses.

In a recent paper published in Nature, researchers at the University of Chicago discovered how to block nicotinamide N-methyl transferase (NNMT), an enzyme that is involved in the progression of high-grade serous ovarian cancer. The team showed that NNMT promotes cancer growth by helping the tumor evade the immune system, and they also developed a potent NNMT inhibitor that could help overcome therapy resistance, providing a new and effective strategy for treating ovarian cancer.

Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.

The benefits of exercise and its positive influence on physical and mental health are well documented, but a new Yale and VA Connecticut study sheds light on the role genetics plays for physical activity, accounting for some of the differences between individuals and showing differences in biology for physical activity at leisure versus physical activity at work and at home.

Many clinicians remain unaware of the health risks linked to PFAS, short for perfluoroalkyl and polyfluoroalkyl substances, despite rising medical and public awareness of the chemicals and their toxicity. PFAS can affect nearly every organ system and linger in our bodies for decades, raising risks of cancer, immune deficiencies, and pregnancy complications.

About 90,000 people are diagnosed with Parkinson's disease (PD) each year—one person every six minutes. While most people associate PD with tremors and stiffness, the condition is far more complex than these symptoms and may affect more than just movement.

24 July 2025, Cairo, Egypt – On 17 July 2025, the World Health Organization (WHO) Regional Office for the Eastern Mediterranean launched the Regional Coalition for Mental Health and Substance Use Prevention. A webinar held for the launch brought together civil society organizations (CSOs) working on mental health and substance use from across the Region. Speakers from the Regional Office included Regional Director Dr Hanan Balkhy, Director of Programme Management Dr Adham Ismail, Regional Advisor Dr Khalid Saeed, and Technical Officer Dr Dalia Elasi.  Other speakers included the Director of Partnerships and Secretariat Lead at the Global Mental Health Action Network (GMHAN) Dr Antonis Kousoulis, GMHAN Officer Ms Divya Sharma, President of Justice for Health Sasha Hajj-Assaf, and representatives from key member organizations. The Coalition aims to promote mental health literacy, prevent substance use and reduce stigma by meaningfully engaging and empowering people with lived experience (PWLE) and their organizations. It is hosted on an interactive platform in collaboration with GMHAN, led by United for Global Mental Health. The platform includes links to the websites of member organizations and a unique engagement space GMHAN Circle. The dedicated page Civil Society Speaks highlights success stories on programmes, initiatives and campaigns for mental health and substance use, implemented and shared by CSOs across the Region. The Coalition’s mandate aligns with the WHO’s Read more...

The combination of a recently approved blood test for detection of Alzheimer's disease combined with two medications that slow progression of the disease is drastically improving outcomes for patients and their families, according to a neurologist and surgeon at Yale New Haven Health.

A GOP-led Congress has approved $186 billion in cuts to the food assistance program through 2034. The second Trump administration has said that healthy eating is a priority.