AI tool more effective for predicting risk of heart attack

Scientists at The Wistar Institute have discovered that a class of FDA-approved cancer drugs known as PARP1 inhibitors can effectively combat Epstein-Barr virus (EBV)-driven lymphomas. The findings, published in the Journal of Medical Virology, demonstrate that these drugs, which work by blocking the activity of the PARP1 enzyme, can halt tumor growth by interfering with the EBV's ability to activate key cancer-promoting genes.

A research study establishes a strong correlation between distressed births and experiencing mental and physical problems later in life.

The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has shown, hair follicle stem cells (HFSCs) can switch teams, pitching in to heal the skin when it receives an injury. How do these cells know it's time to pivot?

Intermittent fasting is as effective as traditional calorie-restriction diets for weight loss, according to a new review of evidence led by University of Toronto researchers.

A new study conducted in Lake County, California—one of the most wildfire-affected regions in the country—has found that residents' anxiety and stress about climate change are associated with increased disaster-preparedness behaviors.

Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.

A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels. The findings were recently published in Science Signaling.

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed. This groundbreaking research offers fresh hope for millions of people living with dopamine-related disorders, marking a significant advance in the quest for precision-based neuroscience and medicine.

Can artificial intelligence (AI) potentially transform health care for the better?

Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cells in the human brain, according to the latest calculations. These cell types vary in their function, in the number and length of their cellular appendages, and in their interconnections. They emit different neurotransmitters into our synapses, and depending on the region of the brain—for example, the cerebral cortex or the midbrain—different cell types are active.

Researchers have published a paper in Alzheimer's & Dementia, titled "ApoE3 Christchurch and tau interaction as a protective mechanism against Alzheimer's disease."

Women with type 2 diabetes are nearly twice as likely as men to have hidden heart damage, according to a study by University of Leicester researchers.

Imagine having blocked arteries in your legs and not knowing it. At first, there may be no symptoms at all. Just occasional fatigue, cramping or discomfort—symptoms easy to dismiss as aging or being out of shape.

Researchers from the University of Maryland's Department of Nutrition and Food Science are shedding new light on how a dangerous food-borne pathogen—Cronobacter sakazakii—may have adapted to thrive in dried and powdered foods across the global supply chain.

When a child struggles to tie their shoelaces, write legibly or stay upright during PE, it can be dismissed as clumsiness or lack of effort. But for around 5% of UK children, these challenges stem from a neurodevelopmental condition known as developmental coordination disorder (DCD), also known as dyspraxia. And new findings reveal how deeply it's impacting their lives—at home, in school and in their future.

As the popularity of medications for weight loss, such as Ozempic and Wegovy, surges across North America, new research raises important concerns about their use among adolescent boys and young men.

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center may help explain why certain liver tumors return quickly after thermal ablation, a widely used minimally-invasive, image-guided technique that kills cancer cells by applying intense heat through a needle-like probe.

Our genes underlie all aspects of life, from our looks to how our cells behave. This includes diseases, as genetic changes can underlie the development and progression of certain health problems. This is true for arteriovenous malformations (AVMs), vascular anomalies that are known to be life-threatening. However, the biological mechanisms driving their growth have remained unclear until now.