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Most patients with advanced melanoma remain disease-free 4 years after pre-surgical immunotherapy, study finds

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  • 2025-07-11 03:00 event
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Most patients with advanced melanoma remain disease-free 4 years after pre-surgical immunotherapy, study finds
Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.

61. Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks

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Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.

62. Study finds fewer complications after additional ultrasound in pregnant women who feel less fetal movement

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It can be difficult to decide whether to expedite birth when a woman in the final stage of pregnancy perceives fewer fetal movements. An additional ultrasound measurement to assess resistance in fetal blood vessels can help make this decision more accurately, leading to fewer complications during delivery.

63. Living in marginalized neighborhoods linked to adverse outcomes in acute myocardial infarction

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For younger acute myocardial infarction (AMI) survivors, living in marginalized neighborhoods is associated with adverse outcomes, according to a study published online July 2 in JAMA Network Open.

64. Children sweat at same rate as adults in extreme heat, study finds

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New research from the University of Sydney has found that children are at a similar risk of dehydration and hyperthermia in extreme heat as adults, contradicting previous advice that children are more susceptible to heat-related illnesses.

65. An FDA-approved drug halts Epstein-Barr virus-driven lymphoma by disrupting a key cancer pathway

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Scientists at The Wistar Institute have discovered that a class of FDA-approved cancer drugs known as PARP1 inhibitors can effectively combat Epstein-Barr virus (EBV)-driven lymphomas. The findings, published in the Journal of Medical Virology, demonstrate that these drugs, which work by blocking the activity of the PARP1 enzyme, can halt tumor growth by interfering with the EBV's ability to activate key cancer-promoting genes.

66. Research links birth issues to adult health deficits

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A research study establishes a strong correlation between distressed births and experiencing mental and physical problems later in life.

67. Reducing dietary serine may help hair follicle stem cells heal skin wounds faster

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The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has shown, hair follicle stem cells (HFSCs) can switch teams, pitching in to heal the skin when it receives an injury. How do these cells know it's time to pivot?

68. Intermittent fasting as effective for weight loss as traditional dieting, says study

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Intermittent fasting is as effective as traditional calorie-restriction diets for weight loss, according to a new review of evidence led by University of Toronto researchers.

69. Climate change anxiety is a hidden force driving disaster preparedness in California's fire country

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A new study conducted in Lake County, California—one of the most wildfire-affected regions in the country—has found that residents' anxiety and stress about climate change are associated with increased disaster-preparedness behaviors.

70. Most patients with advanced melanoma remain disease-free 4 years after pre-surgical immunotherapy, study finds

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Four years after pre-surgery treatment with a novel combination of immune checkpoint inhibitors, nivolumab and relatlimab, 87% of patients with stage III melanoma remained alive, according to new results from a study led by researchers at The University of Texas MD Anderson Cancer Center.

71. New research uncovers link between cancer pathway and blood-retina barrier function

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A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood vessels. The findings were recently published in Science Signaling.

72. Advanced microscopy reveals that dopamine operates with surgical precision, not as a broad signal

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A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed. This groundbreaking research offers fresh hope for millions of people living with dopamine-related disorders, marking a significant advance in the quest for precision-based neuroscience and medicine.

73. New AI tool gives a helping hand to X-ray diagnosis

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Can artificial intelligence (AI) potentially transform health care for the better?

74. AI tool more effective for predicting risk of heart attack

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Researchers from The University of Western Australia, working with medtech industry partners Artrya, have developed a new, fully automated AI algorithm that is more effective than current methods at predicting the risk of heart attack. The research is published in the journal Circulation: Cardiovascular Imaging.

75. Looking to study neurological conditions, researchers produce over 400 different types of nerve cells

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Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cells in the human brain, according to the latest calculations. These cell types vary in their function, in the number and length of their cellular appendages, and in their interconnections. They emit different neurotransmitters into our synapses, and depending on the region of the brain—for example, the cerebral cortex or the midbrain—different cell types are active.

76. Q&A: Team discusses uncovering ApoE3 Christchurch's multi-pathway defense against Alzheimer's

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Researchers have published a paper in Alzheimer's & Dementia, titled "ApoE3 Christchurch and tau interaction as a protective mechanism against Alzheimer's disease."

77. Hidden heart risks exist in women with type 2 diabetes

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Women with type 2 diabetes are nearly twice as likely as men to have hidden heart damage, according to a study by University of Leicester researchers.

78. A one minute scan of your foot could help prevent amputation: Here's how

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Imagine having blocked arteries in your legs and not knowing it. At first, there may be no symptoms at all. Just occasional fatigue, cramping or discomfort—symptoms easy to dismiss as aging or being out of shape.

79. Researchers find genetic clues to infant formula pathogen's global persistence

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Researchers from the University of Maryland's Department of Nutrition and Food Science are shedding new light on how a dangerous food-borne pathogen—Cronobacter sakazakii—may have adapted to thrive in dried and powdered foods across the global supply chain.

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