Altered gut immune system in Alzheimer's mouse model provides new target for therapeutics

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease (CVD), according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

Asystole is the most serious form of cardiac arrest. It happens when the heart stops beating and there is no more electrical activity. It is sometimes called "flat-line" or "flat-lining" because the lines on an electrocardiogram become flat when electrical activity ceases.

A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study led by researchers at Oxford Population Health. The results of the Active Monitoring for Atrial Fibrillation (AMALFI) trial have been published in the American Heart Journal and were presented at the European Society of Cardiology Congress 2025.

Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete islets. These islets efficiently respond to blood glucose concentration changes, demonstrating very effective blood sugar control capabilities.

Antibiotics are the old medicine cabinet standby for treating infections caused by multidrug-resistant Staphylococcus aureus, but as antimicrobial resistance continues to mount globally, scientists say there's a need for new strategies.

While the grip of the opioid epidemic is loosening, thanks in part to extensive public health efforts and rescue medications like Narcan, deaths from accidental overdose still threaten those who use synthetic opioids like fentanyl. The drug is increasingly mixed with other potent substances, including animal tranquilizers such as xylazine, making it even more dangerous.

A research team has used multi-emission metal organic framework hydrogel (Eu-Dy MOF gel) to construct a noninvasive wearable eye patch fluorescence sensor, combined with the color recognition function of a smartphone to analyze and monitor lysozyme in tears.

At least 95 people in 14 states have been sickened in a salmonella outbreak tied to recalled eggs, federal health officials say.

Young children with attention deficit/hyperactivity disorder often receive medication just after being diagnosed, which contravenes treatment guidelines endorsed by the American Academy of Pediatrics, a Stanford Medicine-led study has found.

Prolonged extreme heat in New Orleans was linked to a measurable increase in domestic violence-related emergency calls, according to new research in JAMA Network Open co-authored by the Tulane University's Newcomb Institute.

UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment—all without the need to customize treatment for each individual patient.

Federal health officials have cut back a long-running program that tracks foodborne illnesses in the United States.

Two people have died after eating raw oysters infected with the flesh-eating bacteria Vibrio vulnificus, Louisiana health officials confirmed.

Cancer cells provide healthy neighboring cells with additional mitochondria to put them to work. This has been demonstrated by researchers at ETH Zurich in a new study. In this way, cancer is exploiting a mechanism that frequently serves to repair damaged cells.

Updated ESC/EACTS Guidelines, being released at the ESC Congress 2025, aim to improve the way that patients with valvular heart disease are diagnosed and treated, responding to robust new evidence that suggests some newer and less invasive treatments could be offered more widely and consistently to patients.

Updated ESC Guidelines, published at ESC Congress 2025 and featured in the European Heart Journal, put a focus on a woman's autonomy in making her own reproductive choices by promoting transparent dialogue and shared decision-making for pregnancies that are high-risk of an adverse maternal and/or fetal event.

A new ESC/EAS Focused Update to guidelines, about how best to manage lipid levels in patients to reduce cardiovascular risk, recommends the use of new cardiovascular risk prediction algorithms. The update was released at ESC Congress 2025 and published in the European Heart Journal.

New ESC Guidelines to improve the diagnosis and care of patients with myocarditis and pericarditis have been published at ESC Congress 2025 and also appear in the European Heart Journal.