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Stem cell research takes a step toward smart blood sugar control in diabetes

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  • 2025-08-29 23:06 event
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Stem cell research takes a step toward smart blood sugar control in diabetes
Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete islets. These islets efficiently respond to blood glucose concentration changes, demonstrating very effective blood sugar control capabilities.

1.325. Cholera outbreaks worsening, spreading to 31 countries: WHO

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The global cholera situation is worsening, with outbreaks across 31 countries and a surging fatality rate, the World Health Organization said Friday.

1.326. Metals and sulfate in air pollution mixture may contribute most to asthma hospitalizations

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Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

1.327. DNA variants that increase testosterone production in PCOS patients identified

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Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). A study has identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS. Using human PCOS cell models, researchers demonstrated that activating these DNA switches turns on DENND1A and drives testosterone production. This provides the first direct evidence that inherited DNA changes can cause the hormone imbalance at the core of PCOS.

1.328. Researchers determine how cells prevent RNA traffic jams under stress

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A University of Michigan study offers fresh insights into how cells manage molecular crises.

1.329. Retinitis pigmentosa mouse models reflect pathobiology of human RP59

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Retinitis pigmentosa retinal degeneration is caused by a family of hereditary mutations in nearly 100 genes that slowly lead to blindness over years or decades.

1.330. Active ingredient from red foxglove helps with heart failure, clinical study confirms

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Digitalis has been used to treat heart failure for more than 200 years. The drug digitoxin also belongs to this group of active ingredients known as cardiac glycosides.

1.331. Common inflammation drug may slow blood mutation, related cardiovascular disease risk

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Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease (CVD), according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

1.332. Large-scale study reveals 'flat-line ECG' indicates poor outcomes for out-of-hospital cardiac arrest

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Asystole is the most serious form of cardiac arrest. It happens when the heart stops beating and there is no more electrical activity. It is sometimes called "flat-line" or "flat-lining" because the lines on an electrocardiogram become flat when electrical activity ceases.

1.333. Home-based heart rhythm screening improves diagnosis of common heart condition

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A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study led by researchers at Oxford Population Health. The results of the Active Monitoring for Atrial Fibrillation (AMALFI) trial have been published in the American Heart Journal and were presented at the European Society of Cardiology Congress 2025.

1.334. Stem cell research takes a step toward smart blood sugar control in diabetes

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Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete islets. These islets efficiently respond to blood glucose concentration changes, demonstrating very effective blood sugar control capabilities.

1.335. Scientists move toward developing vaccine against pathogenic Staphylococcus aureus

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Antibiotics are the old medicine cabinet standby for treating infections caused by multidrug-resistant Staphylococcus aureus, but as antimicrobial resistance continues to mount globally, scientists say there's a need for new strategies.

1.336. Study reveals how a popular fentanyl additive affects breathing and heart rate

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While the grip of the opioid epidemic is loosening, thanks in part to extensive public health efforts and rescue medications like Narcan, deaths from accidental overdose still threaten those who use synthetic opioids like fentanyl. The drug is increasingly mixed with other potent substances, including animal tranquilizers such as xylazine, making it even more dangerous.

1.337. Smart eye patch uses fluorescence to monitor eye health

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A research team has used multi-emission metal organic framework hydrogel (Eu-Dy MOF gel) to construct a noninvasive wearable eye patch fluorescence sensor, combined with the color recognition function of a smartphone to analyze and monitor lysozyme in tears.

1.338. At least 95 sickened in salmonella outbreak linked to recalled eggs

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At least 95 people in 14 states have been sickened in a salmonella outbreak tied to recalled eggs, federal health officials say.

1.339. ADHD drugs are being prescribed too quickly to preschoolers, study finds

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Young children with attention deficit/hyperactivity disorder often receive medication just after being diagnosed, which contravenes treatment guidelines endorsed by the American Academy of Pediatrics, a Stanford Medicine-led study has found.

1.340. Altered gut immune system in Alzheimer's mouse model provides new target for therapeutics

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The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD), providing a potential new therapeutic pathway for the memory-robbing malady.

1.341. Extreme heat linked to spike in domestic violence calls in New Orleans

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Prolonged extreme heat in New Orleans was linked to a measurable increase in domestic violence-related emergency calls, according to new research in JAMA Network Open co-authored by the Tulane University's Newcomb Institute.

1.342. Scientists develop off-the-shelf immunotherapy for metastatic kidney cancer

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UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment—all without the need to customize treatment for each individual patient.

1.343. CDC scales back foodborne illness tracking

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Federal health officials have cut back a long-running program that tracks foodborne illnesses in the United States.

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