Blood stem cell mutations linked to lower risk of late-onset Alzheimer's disease

Adding targeted radiation to chemotherapy prior to surgery may offer better control of pancreatic tumors—potentially reducing the rate of recurrence after treatment, according to a new study from UT Southwestern Medical Center. Published in Clinical Cancer Research, the novel study offers evidence of a more effective approach with biological insights for treating one of the most aggressive and lethal forms of cancer.

College students who want help overcoming high-risk drinking could benefit from a two-pronged approach that combines an individual-focused psychological theory with social network analysis.

Triclosan is an antimicrobial chemical that was for decades added to everyday items like soap, toothpaste, cosmetics and even kitchen utensils and athletic wear, until concerns about potential health risks led manufacturers to phase it out of some products.

A new hydrogel-based platform to preserve live patient-derived tumor tissues in the lab could pave the way for faster, more accurate testing of cancer treatments for patients with peritoneal metastases, a hard-to-treat and often deadly form of abdominal and pelvic cancers.

A new study from Aarhus University challenges the widespread belief that women are naturally "hardwired" to wake up more easily to a crying baby than men. The work is published in the journal Emotion.

Rett syndrome is a devastating rare genetic childhood disorder primarily affecting girls. Merely 1 out of 10,000 girls are born with it and much fewer boys. It is caused by mutations in the MeCP2 gene on the X chromosome, leading to a spectrum of cognitive and physical impairments, including repetitive hand motions, speech difficulties, and seizures.

A new study reveals that air pollution, traditional herbal medicines and other environmental exposures are linked to genetic mutations that may contribute to the development of lung cancer in people with no or hardly any history of smoking.

A new study by investigators from Europe, including the Netherlands and the United Kingdom (UK), has shed light on significant ethical, administrative, regulatory, and logistical (EARL) hurdles in delivering multinational randomized clinical trials. The research was the first to comprehensively quantify these barriers for an international platform trial and emphasizes the need for urgent improvements, particularly in preparing for future public health crises.

Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years. Diseases associated with chronic inflammation, like arthritis or cancer or autoimmune disorders, weigh heavily on human health—and experts anticipate their incidence is on the rise.

Early recovery from drug addiction to opioids and stimulants is physically and mentally demanding, and a long road to recovery.

Researchers have long been interested in how humans and animals make decisions by focusing on trial-and-error behavior informed by recent information. However, the conventional frameworks for understanding these behaviors may overlook certain realities of decision-making because they assume we make the best decisions after taking into account our past experiences.

A study by researchers at Rutgers Health has uncovered a way to precisely identify and target trauma sites in the body within minutes of injury. The findings, published in the journal Med, could revolutionize emergency care by enabling real-time diagnostics and site-specific treatments delivered within minutes of injury.

Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have improved survival following immunotherapy compared to patients without these mutations, according to researchers from The University of Texas MD Anderson Cancer Center.

As smartphones, apps, and wearable devices become more integrated into health care, new research from the University of Surrey is questioning how effective these digital tools are for managing serious conditions like cancer, diabetes and heart diseases.

Australia's generation X—people born between 1962 and 1982—face the highest risk of death from methamphetamine-related causes among all age groups, according to a new Burnet Institute study.

A federal judge has stopped the Trump administration from implementing more layoffs at the U.S. Department of Health and Human Services (HHS), saying the job cuts likely went against the law.

Juvenile fibromyalgia is a chronic pain disorder that mainly affects adolescent girls. A study led by the University of Barcelona shows that resilience—the ability to cope adaptively with adversity—does not reduce the physical symptoms of this chronic disease, but could act as a protective factor at the emotional and brain level.

The number of colorectal cancer cases in people under 50 is rising worldwide, especially in high-income countries. Possible causes include Western diets, obesity, lack of exercise, and the use of antibiotics, especially in early life and adolescence.