Boosting exercise performance in heart failure patients

T-follicular helper (TFH) lymphoma is a blood cancer subgroup that continues to demonstrate a generally poor prognosis, with no standard treatment established to date. Although specific genetic mutations are frequently observed in this disease, the association between genomic abnormalities and clinical features and prognosis remains unclear.

A senior US health official on Tuesday admitted President Donald Trump's administration had gone too far in slashing biomedical research grants worth billions of dollars, and said efforts were underway to restore some of the funding.

More than half of U.S. teens living in households with firearms believe they can access and load a firearm at home. Even when their parents report storing all firearms locked and unloaded, more than one-third of teens still believe they could access and load one. These are the main findings of our new study, published in the journal JAMA Network Open.

Ice baths are everywhere in modern fitness culture. From professional athletes to weekend warriors, many swear by the post-workout plunge, hoping the icy shock will ease soreness, calm inflammation and help their bodies bounce back faster. But recent research from the Netherlands reveals a surprising downside: Those freezing dips might actually slow muscle growth.

A study in Nature Communications reveals, for the first time, how the transcriptomic profile of human tuberculosis lung lesions is correlated with clinical data from the same patients.

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors. While similar treatments have worked well for blood cancers, treating solid tumors is more difficult. Their method, published in the Journal for ImmunoTherapy of Cancer, targeted a protein found in high amounts on many types of cancer cells (Eva1), and successfully eliminated tumors in lab mice.

Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord. They function by eliminating infectious microbes, dead cells, and aggregated proteins, as well as soluble antigens that may endanger the brain and, during development, also help shape neural circuits enabling specific brain functions.

A person's level of social and economic status can shape their brain heath in later life, a study suggests. Research led by the University of Edinburgh found a connection between socioeconomic status and changes in the white matter of the brain—a known risk factor of cognitive decline and dementia in older age.

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is common for most RNA strands, it forms a closed loop. Known as circular RNAs (circRNAs), these molecules are crucial for development, thought, and synaptic function, yet their high prevalence in neurons has long been a scientific mystery. How does the brain produce so many of them?

A new study to be presented at the SLEEP 2025 annual meeting found that teens who get moderate—but not excessive—catch-up sleep on weekends have fewer symptoms of anxiety.

A new study conducted by researchers at the Hebrew University of Jerusalem reveals how seemingly irrelevant visual cues—known as peripheral information—can significantly influence emotional responses, especially among individuals with depressive symptoms.

Northwestern scientists investigating severe malaria infections in children have uncovered key biological markers that could help guide future treatments, according to a study published in Nature Communications.

Sports clubs have the potential to provide a profound and positive impact on the mental health of their younger members, but the whole club must be engaged to make a real difference.

A new national audit has revealed that more than half of Australia's diagnostic imaging clinics are now owned by large for-profit corporations, raising questions about health care access, cost and quality amid growing corporatization in the sector.

Infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence compared to children who were healthy as newborns. This is according to a study from Karolinska Institutet published in the journal JAMA Pediatrics titled "Severe Neonatal Morbidity and All-Cause and Cause-Specific Mortality Through Infancy and Late Adolescence."

The discovery of two new genetic disorders comes from a study delivered through the National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Center (BRC) and The University of Manchester and could provide answers for several thousands of people with neurodevelopmental conditions around the world.

A simple, short questionnaire designed by an Edith Cowan University (ECU) researcher could help people better understand and track their emotional well-being with minimal time and effort.

Scientists know the stomach talks to the brain, but two new studies from Rutgers Health researchers suggest the conversation is really a tug-of-war, with one side urging another bite, the other signaling "enough."