Key biological markers in severe malaria could pave path for future treatments

Ice baths are everywhere in modern fitness culture. From professional athletes to weekend warriors, many swear by the post-workout plunge, hoping the icy shock will ease soreness, calm inflammation and help their bodies bounce back faster. But recent research from the Netherlands reveals a surprising downside: Those freezing dips might actually slow muscle growth.

A study in Nature Communications reveals, for the first time, how the transcriptomic profile of human tuberculosis lung lesions is correlated with clinical data from the same patients.

CAR-T cells are specialized immune cells genetically modified to recognize and attack cancer cells. Researchers at Nagoya University in Japan and their collaborators have developed new CAR-T cells to target malignant tumors. While similar treatments have worked well for blood cancers, treating solid tumors is more difficult. Their method, published in the Journal for ImmunoTherapy of Cancer, targeted a protein found in high amounts on many types of cancer cells (Eva1), and successfully eliminated tumors in lab mice.

Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord. They function by eliminating infectious microbes, dead cells, and aggregated proteins, as well as soluble antigens that may endanger the brain and, during development, also help shape neural circuits enabling specific brain functions.

A person's level of social and economic status can shape their brain heath in later life, a study suggests. Research led by the University of Edinburgh found a connection between socioeconomic status and changes in the white matter of the brain—a known risk factor of cognitive decline and dementia in older age.

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is common for most RNA strands, it forms a closed loop. Known as circular RNAs (circRNAs), these molecules are crucial for development, thought, and synaptic function, yet their high prevalence in neurons has long been a scientific mystery. How does the brain produce so many of them?

Heating the lower limbs before exercise has been found to significantly improve endurance in individuals with heart failure.

A new study to be presented at the SLEEP 2025 annual meeting found that teens who get moderate—but not excessive—catch-up sleep on weekends have fewer symptoms of anxiety.

A new study conducted by researchers at the Hebrew University of Jerusalem reveals how seemingly irrelevant visual cues—known as peripheral information—can significantly influence emotional responses, especially among individuals with depressive symptoms.

Sports clubs have the potential to provide a profound and positive impact on the mental health of their younger members, but the whole club must be engaged to make a real difference.

A new national audit has revealed that more than half of Australia's diagnostic imaging clinics are now owned by large for-profit corporations, raising questions about health care access, cost and quality amid growing corporatization in the sector.

Infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence compared to children who were healthy as newborns. This is according to a study from Karolinska Institutet published in the journal JAMA Pediatrics titled "Severe Neonatal Morbidity and All-Cause and Cause-Specific Mortality Through Infancy and Late Adolescence."

The discovery of two new genetic disorders comes from a study delivered through the National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Center (BRC) and The University of Manchester and could provide answers for several thousands of people with neurodevelopmental conditions around the world.

A simple, short questionnaire designed by an Edith Cowan University (ECU) researcher could help people better understand and track their emotional well-being with minimal time and effort.

Scientists know the stomach talks to the brain, but two new studies from Rutgers Health researchers suggest the conversation is really a tug-of-war, with one side urging another bite, the other signaling "enough."

Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have made one of the most important discoveries to date in the study and treatment of BRCA1-deficient cancers and drug resistance.

Adolescents and young adults (AYAs) with cancer face numerous challenges, including financial toxicity due to the high cost of medical care. This encompasses not only the impact of direct, out-of-pocket expenses for cancer treatment, but also indirect costs due to disruptions in education or employment, resulting psychological distress, and the behaviors with which an individual or household responds to these challenges.

The statistics are hard to ignore: Up to 67 % of female college students in the United States are battling some form of eating disorder, affecting both their mental and physical health during a critical time in their lives. A range of eating disorders exist, varying in severity from mild (body dissatisfaction) to life-threatening (anorexia nervosa).