Brain's metabolic shift explains why APOE4 gene carriers have higher Alzheimer's risk

Prostate cancer relies on genetic "switches," called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers. They further implicate two proteins, p300 and CBP, that add these marks, and along with the androgen receptor, turn on enhancers and promote prostate cancer growth.

Nearly a decade ago, Kristen Beavers, who studies safe ways for older adults to lose weight, began asking whether weighted vests could help this population drop pounds without sacrificing vital bone mass and lean muscle. Now, in 2025, she routinely gets requests from national media, community groups and individuals interested in better ways to work out.

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer. By blocking a specific thyroid hormone receptor, cancer growth was inhibited in both animal models and tumor cell cultures.

A few years ago, I climbed over a gate and found myself gazing down at a valley. After I'd been walking for a few minutes, looking at the fields and the sky, there was a shift in my perception. Everything around me became intensely real. The fields and the bushes and trees and the clouds seemed more vivid, more intricate and beautiful.

Know someone who's been diagnosed with breast cancer? There's a good chance that person has received hormone therapy. Estrogen receptor-positive (ER+) breast cancers account for about 75% of cases. Hormone therapy is one of the most common and effective treatments. However, it's far from a cure.

A major study has found that babies born between 8 and 10 weeks early can be fed with milk through a tube in their stomach straight after birth rather than being given intravenous feeds through a drip.

Findings from the multisite IGNITE clinical trial suggest that arterial stiffness, which occurs when large blood vessels lose their natural flexibility, may be linked to greater injury effects to brain nerve fibers in older adults without cognitive impairment. Understanding this relationship may help researchers and clinicians identify older adults who could be more at risk of developing cognitive decline.

Routine data from laboratories reveal a decline in vitamin D levels during the COVID-19 pandemic, especially in older women and urban dwellers. The COVID-19 pandemic had effects on human health well beyond the infections themselves. A research team led by LMU epidemiologist Professor Eva Grill has demonstrated for the first time at the population level that vitamin D levels were significantly lower during the pandemic than before.

A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson's disease show significantly less brain atrophy—decreased cortical thickness in the brain—than men, despite similar clinical severity. This discovery, published in the journal Nature Communications, could lead scientists to explore the role that hormones might play in treating the disease.

A new survey-based study from Northwestern University, which examined the diets of parents across every Chicago neighborhood, has found that parental intake of omega-3 fatty acids falls below recommended levels, with women consuming even lower amounts of omega-3 fatty acids than men. This deficiency may have direct negative effects on children's health.

The proportion of women presenting to Australian general practice with endometriosis almost doubled between 2011 and 2021, according to a new study by Monash University's SPHERE Center of Research Excellence.

Type 2 diabetes (T2D), once considered an adult-onset disease, is increasing at alarming rates in children and adolescents. Before the mid-1990s, just 1% to 2% of youth with diabetes had T2D. Today, that number has skyrocketed to between 24% and 45%, with the average age of diagnosis hovering around 13 years old.

In a finding set to change the way disease is monitored, Chandra Mohan, an international expert and pioneer in lupus research at the University of Houston, is reporting that urine samples can indicate lupus nephritis in a noninvasive manner, without the need for repeat and painful renal biopsies.

A new University of Helsinki analyzed life-course data from over 10,000 individuals aged 50 and above across 28 European countries. The findings suggest that those with a religious upbringing tend to enjoy better physical health in later life and report fewer difficulties with daily activities such as dressing or washing.

Any parent will tell you that raising a child isn't easy. While the experience can be filled with joy and love and fulfillment, emotional, financial and marital stress will present challenges to any family.

They've become as ubiquitous on British high streets as coffee shops—bubble tea outlets offering their Instagram-worthy drinks in countless flavor combinations. The Taiwanese beverage, a blend of black tea, milk, sugar and chewy tapioca pearls, has gained global popularity since its origins in the 1980s. But recent findings suggest this trendy drink may warrant closer scrutiny.

Have you ever tossed and turned under a full moon and wondered if its glow was keeping you awake? For generations, people have believed that the moon has the power to stir up sleepless nights and strange behavior—even madness itself. The word "lunacy" comes directly from luna, Latin for moon.

Stroke can happen to anyone, at any age and at any time. The number of strokes among younger adults under 55 is rising worldwide, and every day in the UK around 240 people experience the traumatic and life-changing effects of a stroke.