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Researchers find a new targeted approach to shut down prostate cancer growth

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  • 2025-10-22 02:41 event
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Researchers find a new targeted approach to shut down prostate cancer growth
Prostate cancer relies on genetic "switches," called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers. They further implicate two proteins, p300 and CBP, that add these marks, and along with the androgen receptor, turn on enhancers and promote prostate cancer growth.

100. Infrared sauna may hold benefits for team-sport athletes

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A study conducted by the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, suggests that using an infrared sauna after exercise can speed up recovery and support performance in team-sport athletes. This method appears particularly promising during busy match schedules.

101. Rare virus transmitted by rats infects woman in Germany: Study links it to private pet rat breeding facility

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Doctors and scientists reported a case of Seoul virus infection in a woman. The Seoul virus belongs to the hantavirus family and can be transmitted by rats. In their publication of the case in the journal Emerging Infectious Diseases, the experts recommend better screening and improved hygiene practices in private rat breeding facilities. They also advocate for raising public awareness of zoonoses, which are diseases that can be transmitted from animals to humans.

102. MRI-based evaluation system accurately quantifies paraspinal muscle atrophy and nerve root injury severity

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A noninvasive MRI technique that measures volumetric changes in paraspinal muscles could transform how doctors assess nerve damage in the cervical spine, which helps guide more precise treatment decisions and potentially speed recovery for patients suffering from either sudden trauma or gradual degeneration.

103. Twin study challenges oversimplified claims about social media and well-being

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A new study published in Behavior Genetics offers a fresh and nuanced perspective on the ongoing debate over social media's impact on well-being.

104. Infant brain patterns linked to future reading issues

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Delays in language and reading development are common, and learning disorders such as dyslexia can significantly affect a child's educational path and later opportunities. The earlier support is given, the easier it is for children to build strong language and reading skills.

105. Recurrence-free survival longer with nivolumab than ipilimumab in melanoma: Study

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For patients with resected stage IIIB-C or stage IV melanoma, recurrence-free survival is longer with nivolumab than ipilimumab, according to a study published online Oct. 18 in the New England Journal of Medicine to coincide with the annual meeting of the European Society for Medical Oncology, held from Oct. 17 to 21 in Berlin.

106. Stress caused by family structure changes in infancy can triple psoriasis risk later in life

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New longitudinal research reveals that severe stress caused by changes in family structure like divorce or separation experienced during the first year of life may triple the risk of developing psoriasis later in life.

107. Investigations of recurring Salmonella Strathcona outbreaks in Europe point to common source

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In 2011, a rare type of Salmonella was reported for the first time in Europe connected to an outbreak in several European countries. At the time, outbreak investigations pointed to small tomatoes from Sicily (Italy) as the likely source for the salmonellosis cases caused by Salmonella Strathcona.

108. Acoustic neuromodulation, customized to each person's brainwave patterns, may improve well-being

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A new study from Wake Forest University School of Medicine, published online in Global Advances in Integrative Medicine and Health, reveals that use of a brief, noninvasive intervention offers meaningful relief for health care workers in the reduction of stress-related symptoms. This approach uses acoustic neuromodulation guided by each participant's unique brainwave activity, creating tailored sound sequences that help restore balance and reduce stress-related symptoms.

109. Researchers find a new targeted approach to shut down prostate cancer growth

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Prostate cancer relies on genetic "switches," called enhancers, that can turn on tumor-promoting genes. Researchers at the University of Michigan Health Rogel Cancer Center have discovered histone H2B N-terminal acetylation (H2BNTac), an essential chemical mark of these enhancers. They further implicate two proteins, p300 and CBP, that add these marks, and along with the androgen receptor, turn on enhancers and promote prostate cancer growth.

110. Q&A: Putting weighted vests to the test—here's what research shows

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Nearly a decade ago, Kristen Beavers, who studies safe ways for older adults to lose weight, began asking whether weighted vests could help this population drop pounds without sacrificing vital bone mass and lean muscle. Now, in 2025, she routinely gets requests from national media, community groups and individuals interested in better ways to work out.

111. Blocking thyroid hormone receptor offers new approach to prostate cancer treatment

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An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer. By blocking a specific thyroid hormone receptor, cancer growth was inhibited in both animal models and tumor cell cultures.

112. How higher states of consciousness can forever change your perception of reality

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A few years ago, I climbed over a gate and found myself gazing down at a valley. After I'd been walking for a few minutes, looking at the fields and the sky, there was a shift in my perception. Everything around me became intensely real. The fields and the bushes and trees and the clouds seemed more vivid, more intricate and beautiful.

113. Breast cancer protein discovery could restore hormone therapy response

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Know someone who's been diagnosed with breast cancer? There's a good chance that person has received hormone therapy. Estrogen receptor-positive (ER+) breast cancers account for about 75% of cases. Hormone therapy is one of the most common and effective treatments. However, it's far from a cure.

114. Some babies born 8–10 weeks early can be safely fed milk without risk of gut complications

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A major study has found that babies born between 8 and 10 weeks early can be fed with milk through a tube in their stomach straight after birth rather than being given intravenous feeds through a drip.

115. Stiff arteries may amplify early memory decline in older adults

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Findings from the multisite IGNITE clinical trial suggest that arterial stiffness, which occurs when large blood vessels lose their natural flexibility, may be linked to greater injury effects to brain nerve fibers in older adults without cognitive impairment. Understanding this relationship may help researchers and clinicians identify older adults who could be more at risk of developing cognitive decline.

116. COVID-19: Vitamin D levels fell during pandemic for older women and urban dwellers

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Routine data from laboratories reveal a decline in vitamin D levels during the COVID-19 pandemic, especially in older women and urban dwellers. The COVID-19 pandemic had effects on human health well beyond the infections themselves. A research team led by LMU epidemiologist Professor Eva Grill has demonstrated for the first time at the population level that vitamin D levels were significantly lower during the pandemic than before.

117. Women better protected against early neurodegeneration in Parkinson's disease, study reveals

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A large international study involving nearly 700 participants reveals that women with a precursor condition to Parkinson's disease show significantly less brain atrophy—decreased cortical thickness in the brain—than men, despite similar clinical severity. This discovery, published in the journal Nature Communications, could lead scientists to explore the role that hormones might play in treating the disease.

118. Brain's metabolic shift explains why APOE4 gene carriers have higher Alzheimer's risk

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Researchers from Aarhus University have identified why the gene APOE4 carries a significantly higher risk of developing Alzheimer's disease—a major breakthrough for possible treatment. The study also proves, for the first time, that brain cells can change their "diet" as we age. The findings are published in the journal Nature Metabolism.

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