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CaMKIIα redox mechanism revealed as key to learning and memory

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  • 2025-08-21 22:16 event
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CaMKIIα redox mechanism revealed as key to learning and memory
A research team led by Prof. Chen Chang from the Institute of Biophysics of the Chinese Academy of Sciences, in collaboration with Prof. Huang Zhangjian of China Pharmaceutical University, has uncovered a previously unknown molecular mechanism essential for learning and memory.

74. Weather disasters increase risk for US drug supply chain disruption, research shows

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In 2024, Hurricane Helene triggered a nationwide shortage of the country's intravenous (IV) fluids after damaging a facility in North Carolina. A similar IV fluid shortage was caused when Hurricane Maria hit Puerto Rico in 2017.

75. Novel technique scans for health cues using light and skin

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A handheld sensor and innovative technique developed by Texas A&M AgriLife Research scientists could one day offer a noninvasive alternative to food diaries and blood tests when monitoring diet and health.

76. First targeted therapy for rare T-cell lymphoma after CAR T treatment successful

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A team of researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai has successfully treated a rare and aggressive T-cell lymphoma that developed after CAR T-cell therapy for multiple myeloma, marking a first in the field of hematologic cancer research. The findings were published in the New England Journal of Medicine.

77. New CT-based indicator helps doctors predict life-threatening postpartum bleeding cases

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Researchers from Kumamoto University have identified a distinctive CT imaging pattern that can predict which women experiencing severe postpartum hemorrhage (PPH) are most likely to need life-saving interventions.

78. Is moderate drinking actually healthy? Scientists say the idea is outdated

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Whether it's a glass of red wine with dinner or a celebratory cocktail on the weekend, drinking in moderation has long been considered not only socially acceptable but also perhaps even healthy.

79. Drug reshapes tissue architecture to reduce damage in alcohol-related liver disease

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Researchers from the Roger Williams Institute of Liver Studies at King's College London developed two 3D models from human tissue to understand the effects that a drug—a cyclophilin inhibitor—has on liver tissue damaged by alcohol. They found that the drug stops the build-up of proteins responsible for making the tissue stiff—a characteristic of liver disease—allowing the liver to remodel itself back to a healthier state.

80. First mechanism for cognitive disorders in schizophrenia found

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Schizophrenia is a debilitating mental disorder affecting around 1% of the population worldwide, and is notoriously difficult to treat. Current medications for schizophrenia can ameliorate positive symptoms, such as hallucinations and delusions. However, there is still a huge unmet medical need for treating negative symptoms, including social withdrawal and lack of motivation, and cognitive symptoms, including impaired attention and memory function.

81. AI-generated genomes could accelerate precision medicine without compromising patient confidentiality

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A new AI system that creates simulated cancer genomes could reshape the tools used to analyze tumors, helping bring about more accurate cancer diagnosis and ultimately more effective treatments.

82. Comorbidities in HIV: Big data study reveals molecular links

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Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at the Center for Individualized Infection Medicine (CiiM) investigated this question as part of the 2000HIV study, a multi-omics cohort coordinated by several research centers in the Netherlands.

83. CaMKIIα redox mechanism revealed as key to learning and memory

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A research team led by Prof. Chen Chang from the Institute of Biophysics of the Chinese Academy of Sciences, in collaboration with Prof. Huang Zhangjian of China Pharmaceutical University, has uncovered a previously unknown molecular mechanism essential for learning and memory.

84. CRISPR screening identifies key targets to strengthen CAR NK cell therapies

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Natural killer (NK) cells became markedly better at killing cancer cells after scientists removed key gene targets identified through a new genome-wide CRISPR screening tool, according to new research from the University of Texas MD Anderson Cancer Center.

85. Ambient documentation technologies reduce physician burnout and restore 'joy' in medicine, study shows

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A study led by Mass General Brigham researchers reveals that ambient documentation technologies—generative artificial intelligence scribes that record patient visits and draft clinical notes for physician review before incorporating into electronic health records—led to significant reductions in physician burnout.

86. Computational approach meets biology to connect neural progenitor cells with human disorders

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For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis—the birth of new neurons—is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.

87. Do you take your own blood pressure at home? Here's how to choose the device that fits your arm best

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About 1 in 3 Australian adults have hypertension, or high blood pressure.

88. Pediatricians' association recommends COVID-19 vaccines for toddlers and some older children, breaking with CDC guidance

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For 30 years, vaccine recommendations from the Centers for Disease Control and Prevention have aligned closely with those from the American Academy of Pediatrics, or AAP. But on Aug. 19, 2025, the AAP published new vaccine recommendations that diverge from those of the CDC.

89. Predictive simulations seek to minimize the risk of falls in older age

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A German-Dutch research team, including scientists from the University of Bayreuth, has investigated how age-related changes contribute to an increased risk of falling in older adults. Using computer simulations, they explored specific scenarios involving stepping down from a curb or stair with varying levels of muscle strength and nerve signal speed—both of which tend to decline with age. Their findings have been published in Scientific Reports.

90. New study maps out the timeline of DNA damage for multiple myeloma

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A new study focused on multiple myeloma, the second most common blood cancer, may lead to better ways to group patients by the state of their DNA and define new subtypes of disease to better predict treatment strategies and outcomes.

91. The last 'women of the sea' who dive like aquatic mammals

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New research from the University of St Andrews has found that a remarkable group of women who free dive for seafood without oxygen, spend more time underwater than some diving mammals like sea beavers, and rival others like sea otters and sea lions.

92. Many mothers experience worry and self-blame after giving birth

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A new study from Aarhus University shows that it is normal for many mothers to feel anxious and overwhelmed after childbirth. The researchers hope the study's findings will encourage better conversations between new mothers and health care professionals.

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