First targeted therapy for rare T-cell lymphoma after CAR T treatment successful

In adults with autoimmune pulmonary alveolar proteinosis (aPAP), once-daily inhaled molgramostim, a recombinant human granulocyte-macrophage colony-stimulating factor, leads to a greater increase in pulmonary gas transfer than placebo, according to a study published in the Aug. 21/28 issue of the New England Journal of Medicine.

A new study finds a dramatic increase in safe drinking water when a machine learning-enabled tool created by York University researchers is used to optimize chlorination levels in refugee camp water supplies. Lead author Syed Imran Ali says that the new study shows that the Safe Water Optimization Tool (SWOT) vastly outperforms status-quo guidelines for safe water supply in humanitarian response.

A resident of South Lake Tahoe, California, has been diagnosed with the plague, the state's first human plague infection since 2020.

The U.S. Centers for Disease Control and Prevention (CDC) is finalizing the termination of at least 600 employees this week, including some working in violence prevention programs.

A new study led by researchers at the Icahn School of Medicine at Mount Sinai has found that adding the targeted therapy everolimus to standard carboplatin chemotherapy extends the time before disease progression in patients with advanced triple-negative breast cancer (TNBC), one of the most aggressive and hard-to-treat forms of breast cancer.

From virtual counselors that can hear depression creeping into a person's voice to smart watches that can detect stress, artificial intelligence is poised to revolutionize mental health care for patients with breast cancer.

Could blowing a conch shell help treat sleep apnea? As a doctor working in sleep medicine, this unexpected news story certainly grabbed my attention. My first reaction was skepticism—sleep specialists don't typically prescribe natural objects found on beaches as medical therapy. But perhaps I was too hasty to dismiss the idea.

In 2024, Hurricane Helene triggered a nationwide shortage of the country's intravenous (IV) fluids after damaging a facility in North Carolina. A similar IV fluid shortage was caused when Hurricane Maria hit Puerto Rico in 2017.

A handheld sensor and innovative technique developed by Texas A&M AgriLife Research scientists could one day offer a noninvasive alternative to food diaries and blood tests when monitoring diet and health.

Researchers from Kumamoto University have identified a distinctive CT imaging pattern that can predict which women experiencing severe postpartum hemorrhage (PPH) are most likely to need life-saving interventions.

Whether it's a glass of red wine with dinner or a celebratory cocktail on the weekend, drinking in moderation has long been considered not only socially acceptable but also perhaps even healthy.

Researchers from the Roger Williams Institute of Liver Studies at King's College London developed two 3D models from human tissue to understand the effects that a drug—a cyclophilin inhibitor—has on liver tissue damaged by alcohol. They found that the drug stops the build-up of proteins responsible for making the tissue stiff—a characteristic of liver disease—allowing the liver to remodel itself back to a healthier state.

Schizophrenia is a debilitating mental disorder affecting around 1% of the population worldwide, and is notoriously difficult to treat. Current medications for schizophrenia can ameliorate positive symptoms, such as hallucinations and delusions. However, there is still a huge unmet medical need for treating negative symptoms, including social withdrawal and lack of motivation, and cognitive symptoms, including impaired attention and memory function.

A new AI system that creates simulated cancer genomes could reshape the tools used to analyze tumors, helping bring about more accurate cancer diagnosis and ultimately more effective treatments.

Why do people infected with the human immunodeficiency virus (HIV) often suffer from cardiovascular, liver, and other comorbidities? Researchers at the Center for Individualized Infection Medicine (CiiM) investigated this question as part of the 2000HIV study, a multi-omics cohort coordinated by several research centers in the Netherlands.

A research team led by Prof. Chen Chang from the Institute of Biophysics of the Chinese Academy of Sciences, in collaboration with Prof. Huang Zhangjian of China Pharmaceutical University, has uncovered a previously unknown molecular mechanism essential for learning and memory.

Natural killer (NK) cells became markedly better at killing cancer cells after scientists removed key gene targets identified through a new genome-wide CRISPR screening tool, according to new research from the University of Texas MD Anderson Cancer Center.

A study led by Mass General Brigham researchers reveals that ambient documentation technologies—generative artificial intelligence scribes that record patient visits and draft clinical notes for physician review before incorporating into electronic health records—led to significant reductions in physician burnout.