Cutting the diagnosis journey for children born with rare genetic diseases

A research team at the University of Würzburg has gained new insights into the development of kidney tumors in young children. These enable a better risk assessment and could form the basis for targeted screening and improved early detection.

Chronic pain conditions, characterized by persistent or recurrent pain in specific parts of the body, can be highly debilitating and often significantly reduce the quality of life of the individuals experiencing them. Statistics suggest that approximately 20.9% of adults living in the United States have experienced chronic pain at some point in their lives, while 6.9% have experienced severe chronic pain that significantly impacted their daily functioning and well-being.

26 May 2025 Thank you all for being here today.  It is always a pleasure to connect with ACANU—you know the issues and care deeply about the UN.  Let me begin with the World Health Assembl

31 May 2025 Tobacco use is the leading cause of preventable death globally, and a major health challenge in the Eastern Mediterranean Region.  An estimated 37 million children aged 13-1

Researchers have found that central body fat, especially around the abdomen, is more strongly linked to psoriasis risk than total body fat, particularly in women. This link between central fat and psoriasis remained consistent regardless of genetic predisposition, indicating that abdominal fat is an independent risk factor.

Scientists have found that global warming in the Middle East and North Africa is making breast, ovarian, uterine, and cervical cancers more common and more deadly. The rise in rates is small but statistically significant, suggesting a notable increase in cancer risk and fatalities over time.

In February 2024, the U.S. Department of Health and Human Services Panel for the Use of Antiretroviral Agents in Adults and Adolescents with HIV (ARV Guidelines Panel), in collaboration with the American College of Cardiology (ACC), the American Heart Association (AHA), and the HIV Medicine Association (HIVMA), developed statin therapy recommendations for people with HIV (PWH).

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms related to the cognitive decline associated with Alzheimer's disease, the most common dementia. This study, carried out on animal models with the disease, describes for the first time the decisive role of the RTP801 protein in cells known as astrocytes during the progression of this neurodegenerative disease.

Hot flashes, memory loss, difficulty concentrating, mood swings, urinary incontinence and joint pain: these are just some of the more than 100 symptoms associated with the menopause, a natural process that all women go through when they stop ovulating and menstruating, typically between the ages of 45 and 55.

There are differences of opinion in how to assess "seriousness" in genetic conditions. "In Japan, the seriousness of genetic disorders has traditionally been assessed using narrow medical criteria, limiting access to preimplantation genetic testing for monogenic diseases to only a small number of conditions.

A study led by researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the Broad Institute of MIT and Harvard has uncovered critical insights into the biology of embryonal tumor with multilayered rosettes (ETMR), a rare and aggressive brain tumor affecting young children.

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat. In colon cancer, the second most common cause of cancer death, such mutations severely limit therapeutic options.

If you're a fan of the TV show Yellowstone, you'll know the deal—you earn your place on the ranch by being branded. On the show, this means having a red-hot iron pressed into your flesh, leaving a permanent scar of loyalty to Yellowstone Dutton Ranch and its patriarch, John Dutton.

Hypnosis could play a significant role in at least three areas of dental care: managing acute pain during dental procedures, reducing the anxiety associated with visiting the dentist, and alleviating chronic orofacial pain.

Scientists at the Mind, Brain, and Behavior Research Center at the University of Granada (CIMCYC) have revealed how, when faced with highly appetizing and unhealthy food stimuli, many overweight people or those prone to binge eating keep their impulsive system hyperactive, while their reflective or conscious thinking system takes a back seat.

Monoclonal antibodies against SARS-CoV-2 were considered a promising approach for the prevention and therapy of coronavirus infections. However, the ongoing evolution of the virus regularly produces new variants that are no longer neutralized by the antibodies.

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression. Nanoparticle-driven spleen remodeling allowed transplanted mouse, rat, and human islets to restore normal blood sugar in diabetic rodents and cynomolgus macaques.

Climate change and extreme weather events are threatening the sexual and reproductive health (SRH) of young adolescents in Kenya, according to a new study published earlier this month in BMJ Global Health. The study reveals that food, water, and sanitation insecurities are placing young adolescents aged 10–14, especially girls, at increased risk of school dropout, transactional sex, gender-based violence, and early pregnancy.