Disparities seen in continuous glucose monitor Rx by language preference

Efforts in the early 20th century to improve the quality of medical education in the United States led to a steep decline in the number of medical schools and medical school graduates. In a new study, researchers examined the consequences of these medical school closures between 1900 and 1930 for the number of county-level physicians, nurses, and midwives, and for infant, non-infant, and total mortality. The closures led to a 4% reduction in physicians per capita and resulted in declines in infant mortality, non-infant mortality, and total mortality, they found.

A study led by Dana-Farber Cancer Institute researchers found that combining chemotherapy and immunotherapy before surgery for patients with aggressive stage III non-small cell lung cancer that is considered difficult or impossible to surgically remove can help shrink tumors and make surgery possible.

Antidepressants are widely used as a drug based intervention to treat more severe cases of postnatal depression. While they are regularly prescribed, they can provide a limited response. The drugs modulate the gamma-aminobutyric acid (GABA) system—which has a key role in regulating brain activity—and have been proposed as an effective alternative to antidepressants.

In a multi-institutional study published in the European Urology journal, researchers revealed that testing urine-based tumor DNA (utDNA) can help predict which bladder cancer patients are at higher risk for recurrence after treatment.

A new study found that almost all plans in 40 states and Washington, DC covered at least one form of the opioid overdose reversal drug naloxone, although certain restrictions and quantity limits may still prevent people from accessing this life-saving drug.

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy.

Our brain makes decisions based on direct associations between stimuli in our environment, but it often also does so based on events that initially appear unrelated. How does it achieve this? A recent study by the Cellular Mechanisms in Physiological and Pathological Behavior Research Group at the Hospital del Mar Research Institute, published in Proceedings of the National Academy of Sciences, offers new insights into this process and identifies the brain areas involved.

Homelessness and opioid use disorder are two widespread public health problems in the United States. Providing housing and supportive services, without requiring drug treatment, is a surprisingly cost-effective approach to helping unhoused people with opioid use disorder, Stanford researchers found in a new study in JAMA Network Open.

Once-weekly insulin efsitora alpha (efsitora) is noninferior to once-daily insulin glargine (glargine) for reducing glycated hemoglobin (HbA1c) among adults with type 2 diabetes, according to a study published online June 25 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 20 to 23 in Chicago.

Over thirty percent of adults and children consumed fast food on a given day during August 2021 to August 2023, according to two reports from the National Center for Health Statistics.

Esophageal adenocarcinoma (EAC), one of two major forms of esophageal cancer, is the sixth most deadly cancer worldwide for which no effective targeted therapy exists. Patients need to rely on chemotherapy as a standard-of-care, which is started ahead of surgical interventions as a so-called "neoadjuvant chemotherapy" (NACT) in the hope of shrinking or controlling tumors. However, most patients become resistant to certain NACTs, leading to poor outcomes.

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in Nature Cardiovascular Research. The findings could improve our understanding of congenital heart defects.

Scientists are increasingly finding that the gastrointestinal (GI) tract plays a vital role in our overall health. While its main functions center around digestion, the GI tract is also involved in the production of hormones, immune cells, and even neurotransmitters that can affect mood and brain function. As such, the GI tract is host to many different biomarkers that can be useful for identifying, monitoring, and treating disease—everything from short-chain fatty acids that are indicators of metabolic syndrome to cytokines that are biomarkers of inflammation.

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

In the cerebral cortex, numerous neurons exchange information through junctions known as synapses. The strength of each synaptic connection changes depending on the activity levels of the neurons involved, and these changes are thought to form the basis of learning and memory.

All hypotheses on how the COVID-19 pandemic began remain open, the World Health Organization said Friday, following an inconclusive four-year investigation that was hamstrung by crucial information being withheld.

Why do some patients with precursors to bone marrow cancer never develop the disease? Researchers from the Department of Forensic Medicine at Aarhus University have discovered that some cells enter a dormant state and create a defense against cancer—a breakthrough that could lead to early treatment.

The World Health Organization insisted Friday that there was no evidence of any harm from an important vaccine ingredient, which a US medical panel voted to oppose this week.