Touch-sensing PIEZO2 ion channel found to also play essential role in coronary vessel development

In a multi-institutional study published in the European Urology journal, researchers revealed that testing urine-based tumor DNA (utDNA) can help predict which bladder cancer patients are at higher risk for recurrence after treatment.

A new study found that almost all plans in 40 states and Washington, DC covered at least one form of the opioid overdose reversal drug naloxone, although certain restrictions and quantity limits may still prevent people from accessing this life-saving drug.

Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy.

Our brain makes decisions based on direct associations between stimuli in our environment, but it often also does so based on events that initially appear unrelated. How does it achieve this? A recent study by the Cellular Mechanisms in Physiological and Pathological Behavior Research Group at the Hospital del Mar Research Institute, published in Proceedings of the National Academy of Sciences, offers new insights into this process and identifies the brain areas involved.

Homelessness and opioid use disorder are two widespread public health problems in the United States. Providing housing and supportive services, without requiring drug treatment, is a surprisingly cost-effective approach to helping unhoused people with opioid use disorder, Stanford researchers found in a new study in JAMA Network Open.

Once-weekly insulin efsitora alpha (efsitora) is noninferior to once-daily insulin glargine (glargine) for reducing glycated hemoglobin (HbA1c) among adults with type 2 diabetes, according to a study published online June 25 in the New England Journal of Medicine to coincide with the annual meeting of the American Diabetes Association, held from June 20 to 23 in Chicago.

For patients with type 2 diabetes (T2D), disparities in continuous glucose monitor (CGM) prescriptions are seen by language preference, with less access to CGM prescriptions for adult patients with non-English language preference (NELP), according to a study published online June 17 in JAMA Network Open.

Over thirty percent of adults and children consumed fast food on a given day during August 2021 to August 2023, according to two reports from the National Center for Health Statistics.

Esophageal adenocarcinoma (EAC), one of two major forms of esophageal cancer, is the sixth most deadly cancer worldwide for which no effective targeted therapy exists. Patients need to rely on chemotherapy as a standard-of-care, which is started ahead of surgical interventions as a so-called "neoadjuvant chemotherapy" (NACT) in the hope of shrinking or controlling tumors. However, most patients become resistant to certain NACTs, leading to poor outcomes.

Scientists are increasingly finding that the gastrointestinal (GI) tract plays a vital role in our overall health. While its main functions center around digestion, the GI tract is also involved in the production of hormones, immune cells, and even neurotransmitters that can affect mood and brain function. As such, the GI tract is host to many different biomarkers that can be useful for identifying, monitoring, and treating disease—everything from short-chain fatty acids that are indicators of metabolic syndrome to cytokines that are biomarkers of inflammation.

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

In the cerebral cortex, numerous neurons exchange information through junctions known as synapses. The strength of each synaptic connection changes depending on the activity levels of the neurons involved, and these changes are thought to form the basis of learning and memory.

All hypotheses on how the COVID-19 pandemic began remain open, the World Health Organization said Friday, following an inconclusive four-year investigation that was hamstrung by crucial information being withheld.

Why do some patients with precursors to bone marrow cancer never develop the disease? Researchers from the Department of Forensic Medicine at Aarhus University have discovered that some cells enter a dormant state and create a defense against cancer—a breakthrough that could lead to early treatment.

The World Health Organization insisted Friday that there was no evidence of any harm from an important vaccine ingredient, which a US medical panel voted to oppose this week.

Mount Sinai researchers have published the first study to use wearable devices to assess how inflammation and symptoms in inflammatory bowel disease (IBD) affect sleep characteristics and sleep patterns over time.

Imagine getting an MRI of your knees and being told you have "mild intrasubstance degeneration of the posterior horn of the medial meniscus."

Proposed measures to impose historic cuts on Medicaid spending could have a devastating impact on millions of older working-age Americans, according to a new analysis conducted by Nari Rhee, director of the Labor Center's Retirement Security Program, and issued by the UC Berkeley Labor Center.