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Drug discovery platform yields optimized compound against SARS-CoV-2 and shows promise against other RNA-based viruses

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  • 2025-10-07 03:50 event
  • 3 hours ago schedule
Drug discovery platform yields optimized compound against SARS-CoV-2 and shows promise against other RNA-based viruses
In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

7.542. 16 Derm-Recommended Products To Use ASAP If You've Been Neglecting Your Skin

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It's not too late to turn it all around.View Entire Post ›

7.543. This Is The Unique Sunscreen Pam And Hailey Have Been Using

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According to Instagram, Bieber counts the multitasking formula among her empties.View Entire Post ›

7.544. Drew Barrymore Is Being Called “Real And Genuine” After Documenting Her “First Perimenopause Hot Flash” On Live TV While Interviewing Jennifer Aniston And Adam Sandler

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“I don’t know that I have ever heard a celebrity talk about a hot flash in the moment. Thank you for being so real.”View Entire Post ›

7.545. This $16 French Moisturizer Is Amazon’s Best-Kept Beauty Secret

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The Embryolisse Lait-Crème Concentré is a multi-tasking hidden gem of a facial cream.View Entire Post ›

7.546. Lila Moss Opened Up About What It Was Like Being Diagnosed With Type 1 Diabetes

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After the model opened up about her experience being diagnosed with type 1 diabetes, we asked experts about the autoimmune condition, the differences between type 1 and type 2 diabetes, and how this diagnosis can change your life.View Entire Post ›

7.547. Why Reviewers Swear By This $28 Tool For Back Pain Relief

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An acupuncturist explains how this scary-looking acupressure mat can help relieve back pain.View Entire Post ›

1. Artificially sweetened and sugary drinks are both associated with an increased risk of liver disease, study finds

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A new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD).

2. Human ability to focus on specific sounds not found to originate in auditory nerve or brainstem

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Research led by the University of Michigan's Kresge Hearing Research Institute and the University of Rochester illuminates the mechanisms through which humans can pick out and focus on single sounds in noisy environments.

3. Study finds psychiatry, primary care, and OB/GYN subspecialties hit hardest by physician attrition

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A nationwide, longitudinal study characterized how physician attrition rates from clinical practice have changed and the factors associated with a differential likelihood of attrition. The study found that the rate of physicians' attrition from clinical practice has increased from 2013 to 2019.

4. Drug discovery platform yields optimized compound against SARS-CoV-2 and shows promise against other RNA-based viruses

  • 3 hours ago schedule
  • medicalxpress.com language

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

5. Long-term analysis finds disease risk, not remission status, determines transplant outcomes in acute myeloid leukemia

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Results of a recently published long-term follow-up of the ASAP trial, which was conducted at universities and clinics across Germany, show that the genetic risk of disease, not remission status, determines overall survival of patients with high-risk acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Furthermore, there is no benefit of remission induction with standard salvage chemotherapy prior to allo-HSCT.

6. Study recommends new grading system for invasive squamous cell carcinoma of the lung

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Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular alterations. Therefore, histopathologic features are increasingly being explored as tools to enhance prognostic accuracy and guide treatment decisions.

7. Common inhalers carry heavy climate cost, study finds

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The inhalers people depend on to breathe are also warming the planet, producing annual emissions equivalent to more than half a million cars in the United States alone, researchers said Monday in a major new study.

8. CDC stops recommending COVID-19 shots for all, leaves decision to patients

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The Centers for Disease Control and Prevention adopted recommendations by a new group of vaccine advisers, and stopped recommending COVID-19 shots for anyone—leaving the choice up to patients.

9. Improving heart health in young adulthood can reduce risk for cardiovascular disease in later life

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Despite progress in past decades to reduce the burden of cardiovascular disease (CVD), it remains the leading cause of death in the U.S. and worldwide. Data within the past 10 years indicate deceleration and reversal of declines in CVD morbidity and mortality. These trends may be further worsened by the prevalence of low heart health, particularly among young adults.

10. Q&A: A novel therapy could calm anxiety for millions of Americans

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Generalized anxiety disorder affects 1 in 20 U.S. adults. Those with serious symptoms may isolate themselves to the point where they rarely leave their home and are unable to work and build meaningful relationships. Standard medications may make little difference.

11. Synaptic changes in the brains of patients with frontotemporal dementia can be modeled in the laboratory

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Neurons produced from frontotemporal dementia patients' skin biopsies using modern stem cell technology recapitulate the synaptic loss and dysfunction detected in the patients' brains, a new study from the University of Eastern Finland shows.

12. FDA may ease warning on hormone therapy for menopause symptoms

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The U.S. Food and Drug Administration (FDA) is reviewing whether to change the warning label on hormone replacement therapy (HRT) drugs used to treat menopause symptoms, a move many experts say is long overdue.

13. Live retinal imaging in mice reveals early immune cell activity before diabetes-related damage occurs

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A new method of taking microscopic images of a live mouse's retina through the eye allows researchers to record the reaction of brain cells to disease and treatment. The Kobe University development is more easily applicable than previous methods and promises to advance research on and treatment of vision-related diseases.

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