Establishing a new global standard for precision medicine in sepsis and critical care

Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular alterations. Therefore, histopathologic features are increasingly being explored as tools to enhance prognostic accuracy and guide treatment decisions.

The inhalers people depend on to breathe are also warming the planet, producing annual emissions equivalent to more than half a million cars in the United States alone, researchers said Monday in a major new study.

The Centers for Disease Control and Prevention adopted recommendations by a new group of vaccine advisers, and stopped recommending COVID-19 shots for anyone—leaving the choice up to patients.

Despite progress in past decades to reduce the burden of cardiovascular disease (CVD), it remains the leading cause of death in the U.S. and worldwide. Data within the past 10 years indicate deceleration and reversal of declines in CVD morbidity and mortality. These trends may be further worsened by the prevalence of low heart health, particularly among young adults.

Generalized anxiety disorder affects 1 in 20 U.S. adults. Those with serious symptoms may isolate themselves to the point where they rarely leave their home and are unable to work and build meaningful relationships. Standard medications may make little difference.

Neurons produced from frontotemporal dementia patients' skin biopsies using modern stem cell technology recapitulate the synaptic loss and dysfunction detected in the patients' brains, a new study from the University of Eastern Finland shows.

The U.S. Food and Drug Administration (FDA) is reviewing whether to change the warning label on hormone replacement therapy (HRT) drugs used to treat menopause symptoms, a move many experts say is long overdue.

A new method of taking microscopic images of a live mouse's retina through the eye allows researchers to record the reaction of brain cells to disease and treatment. The Kobe University development is more easily applicable than previous methods and promises to advance research on and treatment of vision-related diseases.

Nearly 1 in 5 residents (17.8%) of Agder, Norway, reported being discriminated against in the past year. "Discrimination tends to fly under the radar in public discourse. We assume we have legislation and measures in place that work, but this study suggests otherwise," says Jan Georg Friesinger from the University of Agder.

Pancreatic neuroendocrine neoplasms (PNENs) are a rare form of cancer that affects hormone-producing cells in the pancreas. Although uncommon, their incidence has been rising steadily over the past few decades.

Dr. Brian Ciruna had no intention of studying scoliosis, a condition that causes unnatural curvature of the spine. However, the unexpected discovery about a decade ago that zebrafish also develop curved spines left him wondering what was causing the spine to bend and whether there was some connection to the human form of the disease. It turns out that this small, minnow-like fish has a lot to tell researchers about a condition that affects 3% to 4% of children and young teens in Canada.

Researchers at the UNC School of Medicine and the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a leading cause of stroke.

For decades, researchers have worked to unravel the mysteries of post-traumatic epilepsy (PTE), a form of epilepsy that emerges after a traumatic brain injury (TBI). Now, a new study led by Texas A&M University neuroscientist Dr. Samba Reddy offers a sweeping view of how far the science has come and how far it needs to go.

Tobacco smoking is associated with an increased risk of hypertension (high blood pressure), a new UM study has found, and testing patients' urine can help to verify their smoking status and assess this risk.

Chewing on ice may seem harmless, perhaps even refreshing, but dental experts warn it can actually wreak havoc on your teeth.

Most patients with Meniere disease (MD) who undergo cochlear implantation (CI) in the MD-affected ear have stability or improvement of vestibular symptoms, according to a study published in the September issue of Otology & Neurotology Open.

Through new guidelines released today in The Lancet Global Health, leading reproductive health agencies are calling for a major shift in how postpartum hemorrhage (PPH) is prevented, diagnosed and treated. The recommendations highlight the urgent need for earlier detection and faster intervention—steps that could save the lives of tens of thousands of women each year.

The lifetime risk for heart failure has increased to 24%, according to a report published online Sept. 22 in the Journal of Cardiac Failure.