FDA offers speedier approvals to drug companies aligning with 'national priorities'

The US Food and Drug Administration on Wednesday approved Gilead Sciences' twice-yearly injection to prevent HIV, a move the company hailed as a major breakthrough in the fight against the sexually transmitted virus.

The difference between the brain's predicted age and actual chronological age, called a brain age gap, may influence the relationship between cognitive impairment risk factors, like high blood pressure and diabetes, and a person's cognitive performance, also known as thinking and memory skills, according to a study published in Neurology.

The COVID-19 variant that may be driving a recent rise in cases in some parts of the world has earned a new nickname: "razor blade throat" COVID.

Having poor access to food, living in a disadvantaged neighborhood and not having strong friend and family support may lead to worse outcomes after stroke, according to a study published in Neurology Clinical Practice.

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered that "natural killer" cells (NK), a type of immune cell, may actually be hindering the immune system's ability to attack tumors in patients who don't respond to immune checkpoint blockade therapies (ICB), a form of immune therapy. The findings of the study have been published in Cancer Discovery.

A landmark narrative review published in Osteoporosis International reveals critical insights into how diabetes mellitus alters bone microarchitecture and influences fracture risk.

Motor neurons are nerve cells that control our muscles by sending signals from the brain and spinal cord out to the body. In diseases such as Amyotrophic Lateral Sclerosis (ALS), these cells are destroyed, leading to muscle weakness and paralysis. On average, expected survival after diagnosis is about four years, as the patient's ability to move and breathe gradually deteriorates. There is no cure yet, but some drugs can slow the progression of the disease.

Extreme weather events driven by climate change have profound consequences for the sexual and reproductive health of young refugees in Uganda, according to a study published in Global Public Health.

Acute pancreatitis is among the most common gastrointestinal conditions requiring inpatient hospital care in the United States.

In the largest study of its kind, researchers from The University of Texas MD Anderson Cancer Center identified three subgroups of patients with large B-cell lymphoma (LBCL) who have different levels of benefit from CD19 chimeric antigen receptor (CAR) T cell therapy.

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

A study published by researchers at University Hospitals Connor Whole Health and Case Western Reserve University School of Medicine has revealed that Whole Systems Traditional Chinese Medicine (WS-TCM), when integrated with in vitro fertilization (IVF), significantly improves patient-reported levels of stress, pain, and anxiety within a single treatment session. The researchers are also among the first to describe the real-world integration of WS-TCM treatments such as acupuncture within a fertility clinic at a U.S. academic medical center.

In a study of newborn piglets, infection with influenza A was associated with disruptions in the piglets' nasal and gut microbiomes, and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory. Maternal vaccination against the virus during pregnancy appeared to offer some protection from those changes in the piglets.

A new international study coordinated by the European Alzheimer's and Dementia Biobank (EADB) consortium sheds light on how genetic risk factors for Alzheimer's disease (AD) vary—and remain consistent—across global populations. The study represents the first worldwide examination of polygenic risk scores (PRS) and their relationship to the likelihood of developing Alzheimer's disease.

A new review, published in Microbiology, is the first to systematically review the potential effects of psychotropics (the drugs used to treat bipolar disorder) on the gut microbiome of treated and untreated bipolar individuals.

A new paper from Columbia University Mailman School of Public Health, Butler Columbia Aging Center, and Columbia Irving Medical Center introduces a scientific framework for understanding the biological foundation of health—what the researchers term "Intrinsic Health." Published in Science Advances, the study lays the groundwork for measuring and promoting health itself, rather than merely treating disease.

Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis published in PLOS One by Yuan Luo of the First People's Hospital of Neijiang, China.

Hope isn't just wishful thinking—it's a powerful emotional force that gives our lives meaning. Now, a new groundbreaking study from the University of Missouri shows it may be even more essential to well-being than happiness or gratitude.