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Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells—a process called "proteostasis," or protein homeostasis. Brain cells in particular fall prey to proteostasis disruptions, which are linked to the accumulation of protein aggregates in neurodegenerative diseases.
You may have heard the phrase "my heart skipped a beat" when someone was talking about a romantic encounter. In truth, hearts that beat irregularly are dangerous for your health. Atrial fibrillation (AF) is the most common type of irregular heartbeat, and over time, it can worsen and become a permanent condition, a severe disorder that's the leading preventable cause of ischemic stroke, according to the NIH.
Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.
Women who attend prenatal care visits in groups are more likely to continue with their care and have better health outcomes at birth and beyond, according to a University of Michigan study.
What if a computer could read a patient's medical notes and help doctors determine important information for their treatments?
The COVID-19 pandemic upended life for individuals and communities worldwide. Social isolation, health mandates, illness, and economic hardships took a toll on the well-being of families and children, but there were also silver linings to people's experiences.
Robotic surgery is a viable and sometimes advantageous approach for emergency colorectal surgery, a setting in which it has previously been underused and understudied, according to new research findings published in the Journal of the American College of Surgeons.
About 26% of both households and immediate families of older adults include an individual with dementia—often requiring relatives to step into unexpected caregiving roles, according to a new University of Michigan study. The work is published in the journal Alzheimer's & Dementia.
In the latest online gambling surveys conducted by the University of Massachusetts Amherst, monthly gamblers in Massachusetts reported ongoing higher levels of sports betting, gambling intensity and gambling harms, with their attitudes toward gambling continuing to be more negative.
Genes get passed down from parents, determining traits such as eye color and height as well as risk for certain diseases.
Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl. When they emerge from hibernation, they recover from dangerous health changes similar to those seen in type 2 diabetes, Alzheimer's disease, and stroke.
Research from the University of Michigan Medical School finds that one in three hospitalized patients remain connected to a breathing tube after passing a spontaneous breathing trial.
By analyzing tens of thousands of genes, proteins, and protein modifications in hundreds of lung tumors, an international research team has uncovered new factors linked to poor outcomes in lung adenocarcinoma in both smokers and people who have never smoked. These factors include a pattern of DNA damage and signatures of exposures to chemicals found in processed foods and cosmetics. The findings could lead to better precision medicine strategies for this most common type of lung cancer.
Stress internalization is a significant risk factor for age-related cognitive decline in older Chinese Americans, according to Rutgers Health researchers.
The U.S. Food and Drug Administration's (FDA) top vaccine official is stepping down after just three months in a role that upset drug companies, patient groups and some political leaders.
Generative artificial intelligence could take years off the time between identifying public health risks and launching impactful mass media campaigns.
Police officers and staff in England and Wales are frustrated with their uniforms, which they say are unfit for purpose, restrictive and contribute to major health issues.
The immune system is a major determinant of how patients respond to standard treatments for ovarian cancer, the leading cause of death from gynecological malignancies. But little was known about how the immune landscape of tumors changes when patients relapse—as they frequently do—or how those changes influence responses to subsequent therapy, which tend to be dismal.
At a meeting held by the Food and Drug Administration on July 21, 2025, a panel convened by the agency cast doubt on the safety of antidepressant medications called selective serotonin reuptake inhibitors, or SSRIs, in pregnancy.