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Research led by Naval Medical University's Changzheng Hospital in China reports that an off-the-shelf cell therapy built from induced pluripotent stem cells (iPSCs) loosened life-limiting skin and organ scarring in a woman with systemic sclerosis.
Powerful new immunotherapies are offering fresh hope for patients with many different types of cancer.
A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any brains from healthy people, researchers report in the journal JCI Insight.
Starting with the question "How does our brain distinguish glucose from the many nutrients absorbed in the gut?" a KAIST research team has demonstrated that the brain can selectively recognize specific nutrients—particularly glucose—beyond simply detecting total calorie content. Their study, published in Neuron, is expected to offer a new paradigm for appetite control and the treatment of metabolic diseases.
During the menopause transition, only one in five women have optimal scores using the American Heart Association's health-assessment tool, known as Life's Essential 8 (LE8). Among the tool's eight components, four of them—blood glucose, blood pressure, sleep quality and nicotine use—are key in driving future cardiovascular risks, with sleep being particularly crucial for long-term cardiovascular health.
Understanding how the human brain represents the information picked up by the senses is a longstanding objective of neuroscience and psychology studies. Most past studies focusing on the visual cortex, the network of regions in the brain's outer layer known to process visual information, have focused on the contribution of individual regions, as opposed to their collective representation of visual stimuli.
A study by investigators from Mass General Brigham adds evidence that the most effective way to prevent preterm birth among patients with a history of cervical insufficiency is to place a cervical stitch higher in the abdomen rather than vaginally.
A study in Diabetes, Obesity and Metabolism has identified certain characteristics that might influence people's weight loss after taking prescription drugs called glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide (sold under the brand names Ozempic and Wegovy).
The candles on a birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.
Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment.
Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care.
A new study by researchers at the Icahn School of Medicine at Mount Sinai, Memorial Sloan Kettering Cancer Center, and collaborators, suggests that artificial intelligence (AI) could significantly improve how doctors determine the best treatment for cancer patients—by enhancing how tumor samples are analyzed in the lab.
Shorter-form messaging seems to be preferable for recruiting participants to enroll in clinical trials, according to a research letter published online June 25 in the Journal of the American Medical Association.
Exposure to trihalomethanes—especially brominated trihalomethanes—in residential community water supplies (CWS) is associated with an increased risk of chronic kidney disease (CKD), according to a study published online July 2 in JAMA Network Open.
Investigators have developed an artificial intelligence-assisted diagnostic system that can estimate bone mineral density in both the lumbar spine and the femur of the upper leg, based on X-ray images. The advance is described in a study published in the Journal of Orthopaedic Research.
A large prospective study published in Molecular Nutrition and Food Research reveals that a healthy plant-based diet is linked with a reduced risk of inflammatory bowel disease.
Research in Health Economics indicates that introducing school grades—with A as the highest grade and F as a failing grade—at younger ages may negatively affect children's mental health.
Teclistamab-cqyv is a T-cell-engaging bispecific antibody that targets multiple myeloma cells via the B-cell maturation antigen (BCMA) receptor. It received accelerated approval in 2022 for patients treated with four or more lines of prior therapy based on results from the Phase I/II MajesTEC-1 clinical trial.
A mental health hack designed to promote mental well-being could shift how teenagers view themselves—according to new research from the University of East Anglia.