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Shorter-form messaging may be preferable for trial recruitment

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  • 2025-07-09 15:29 event
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Shorter-form messaging may be preferable for trial recruitment
Shorter-form messaging seems to be preferable for recruiting participants to enroll in clinical trials, according to a research letter published online June 25 in the Journal of the American Medical Association.

606. The brain can selectively recognize glucose, offering clues to treat obesity and diabetes

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Starting with the question "How does our brain distinguish glucose from the many nutrients absorbed in the gut?" a KAIST research team has demonstrated that the brain can selectively recognize specific nutrients—particularly glucose—beyond simply detecting total calorie content. Their study, published in Neuron, is expected to offer a new paradigm for appetite control and the treatment of metabolic diseases.

607. In menopause, sleep is vitally important for women's long-term heart health, study finds

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During the menopause transition, only one in five women have optimal scores using the American Heart Association's health-assessment tool, known as Life's Essential 8 (LE8). Among the tool's eight components, four of them—blood glucose, blood pressure, sleep quality and nicotine use—are key in driving future cardiovascular risks, with sleep being particularly crucial for long-term cardiovascular health.

608. Computational models explore how regions of the visual cortex jointly represent visual information

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Understanding how the human brain represents the information picked up by the senses is a longstanding objective of neuroscience and psychology studies. Most past studies focusing on the visual cortex, the network of regions in the brain's outer layer known to process visual information, have focused on the contribution of individual regions, as opposed to their collective representation of visual stimuli.

609. Surgical technique can reduce risk of early preterm birth for patients with cervical insufficiency

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A study by investigators from Mass General Brigham adds evidence that the most effective way to prevent preterm birth among patients with a history of cervical insufficiency is to place a cervical stitch higher in the abdomen rather than vaginally.

610. Which factors affect the success of popular prescription weight loss drugs in individuals?

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A study in Diabetes, Obesity and Metabolism has identified certain characteristics that might influence people's weight loss after taking prescription drugs called glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide (sold under the brand names Ozempic and Wegovy).

611. People with 'young brains' outlive 'old-brained' peers, scientists find

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The candles on a birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

612. Genome editing enables mice to produce their own weight-loss drug for months

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Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment.

613. Major autism study uncovers biologically distinct subtypes, paving the way for precision diagnosis and care

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Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care.

614. Real-time trial shows AI could speed cancer care

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A new study by researchers at the Icahn School of Medicine at Mount Sinai, Memorial Sloan Kettering Cancer Center, and collaborators, suggests that artificial intelligence (AI) could significantly improve how doctors determine the best treatment for cancer patients—by enhancing how tumor samples are analyzed in the lab.

615. Shorter-form messaging may be preferable for trial recruitment

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Shorter-form messaging seems to be preferable for recruiting participants to enroll in clinical trials, according to a research letter published online June 25 in the Journal of the American Medical Association.

616. Exposure to trihalomethanes linked to chronic kidney disease

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Exposure to trihalomethanes—especially brominated trihalomethanes—in residential community water supplies (CWS) is associated with an increased risk of chronic kidney disease (CKD), according to a study published online July 2 in JAMA Network Open.

617. AI–based test detects early signs of osteoporosis from X-ray images

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Investigators have developed an artificial intelligence-assisted diagnostic system that can estimate bone mineral density in both the lumbar spine and the femur of the upper leg, based on X-ray images. The advance is described in a study published in the Journal of Orthopaedic Research.

618. Healthy plant-based diet may help protect against inflammatory bowel disease

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A large prospective study published in Molecular Nutrition and Food Research reveals that a healthy plant-based diet is linked with a reduced risk of inflammatory bowel disease.

619. Earlier school grading linked to increased mental health risks in children

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Research in Health Economics indicates that introducing school grades—with A as the highest grade and F as a failing grade—at younger ages may negatively affect children's mental health.

620. Data show teclistamab can benefit many multiple myeloma patients who would have been ineligible for pivotal trial

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Teclistamab-cqyv is a T-cell-engaging bispecific antibody that targets multiple myeloma cells via the B-cell maturation antigen (BCMA) receptor. It received accelerated approval in 2022 for patients treated with four or more lines of prior therapy based on results from the Phase I/II MajesTEC-1 clinical trial.

621. Can one video change a teen's mindset? New study says yes—but there's a catch

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A mental health hack designed to promote mental well-being could shift how teenagers view themselves—according to new research from the University of East Anglia.

622. Can psychedelic mushrooms turn back the clock? Study suggests psilocybin preserves telomere length

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A compound found in psychedelic mushrooms may have antiaging properties. Researchers at Baylor College of Medicine have found that psilocybin, the active compound in psychedelic mushrooms, may extend both cellular and organismal lifespans.

623. Health system partnership may help cut senior emergency room visits

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An innovative partnership between a health system and local congregations in neighborhoods with high need that provides individual companionship to older adults has found significant reductions in loneliness and a corresponding reduction in emergency department visits.

624. Key mechanisms of enzyme involved in rare metabolic disease identified

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An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The team was coordinated by the Liver Diseases and Computational Chemistry groups at the CIC bioGUNE research center, member of BRTA.

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