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How B-cell receptor types shape lymphoma cell survival and growth

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  • 2025-09-01 22:46 event
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How B-cell receptor types shape lymphoma cell survival and growth
A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to findings published in Science Advances.

1.237. Depression may make learning to avoid unpleasant events harder

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Depression alters how people pursue rewards, but, conversely, whether depressive symptoms influence how people learn to avoid nonrewarding, unpleasant events is less clear.

1.238. Clopidogrel might be better than aspirin for long-term heart disease

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A comprehensive analysis of nearly 29,000 patients with coronary artery disease (CAD) suggests that clopidogrel, a commonly prescribed blood thinner, is more effective than aspirin in preventing serious heart and stroke events, without increasing the risk of major bleeding.

1.239. Kidney donors who give to strangers do just as well as those who give to loved ones

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"Unspecified," "altruistic" or "non-directed" kidney donation refers to a kidney transplant where the donor and recipient do not know each other. These donations are crucial to increasing the number of high-quality kidneys available, but ethical concerns and assumptions that they are inferior to 'specified' donations (usually from a family member or close friend) mean the practice is not widely adopted in many countries around the world.

1.240. Hyperactive blood platelets linked to heart attacks despite standard drug therapy

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Scientists at the University of Augsburg have discovered a particularly active subgroup of blood platelets that may cause heart attacks in people with coronary heart disease despite drug therapy. This discovery may open up new prospects for customized therapies. The research results are published in the European Heart Journal and were presented on August 31 at Europe's largest cardiology congress.

1.241. No significant reduction in death found following comprehensive cardiovascular screening in men aged 60 to 64 years

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An invitation to attend a comprehensive screening examination for the early signs of cardiovascular disease (CVD) did not reduce all-cause death among men aged 60 to 64 years, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1.242. Extended blood-thinning treatment lowers recurrence in at-risk patients with provoked venous thromboembolism: Study

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Apixaban 2.5 mg twice daily significantly reduced symptomatic venous thromboembolism (VTE) recurrence, with a low risk of major bleeding, in patients with provoked VTE and enduring risk factors, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1.243. Worse outcomes with aspirin in high-risk chronic coronary syndrome patients requiring long-term anticoagulation: Trial

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Adding aspirin increased the risk of cardiovascular events, death and major bleeding in high-risk patients with chronic coronary syndrome (CCS) who had prior stenting and were receiving long-term chronic oral anticoagulation (OAC), according to late-breaking research presented in a Hot Line session at the ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

1.244. Drug-coated devices do not improve outcomes in patients with peripheral artery disease, study finds

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Drug-coated stents and balloons were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in two trials in peripheral artery disease (PAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1.245. Asthma chip reveals treatable subtype in 70% of patients

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A simple blood test could make asthma treatment more precise, more effective—and potentially more affordable. Researchers from Karl Landsteiner University of Health Sciences (KL Krems) and the Medical University of Vienna (MedUni Vienna) have developed a molecular allergy chip that detects allergic asthma in individual patients. The paper is published in the journal Allergy.

1.246. How B-cell receptor types shape lymphoma cell survival and growth

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A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to findings published in Science Advances.

1.247. Could diet be fueling pregnancy hypertension? Saliva holds the clues

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During pregnancy, the body becomes particularly vulnerable to chemical exposures that can affect both the mother and the developing fetus. These exposures—often from everyday sources like processed foods, packaging materials, and personal care products—introduce xenobiotic metabolites (XMs) into the body.

1.248. New AI model accurately identifies which atrial fibrillation patients need blood thinners to prevent stroke

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Mount Sinai researchers developed an AI model to make individualized treatment recommendations for atrial fibrillation (AF) patients—helping clinicians accurately decide whether or not to treat them with anticoagulants (blood thinner medications) to prevent stroke, which is currently the standard treatment course in this patient population. This model presents a completely new approach for how clinical decisions are made for AF patients and could represent a potential paradigm shift in this area.

1.249. Urine test can assess risk of kidney cancer recurrence

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A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent X-ray examinations and thus reduce the associated radiation, anxiety and costs.

1.250. No benefit found when biomarker-based risk scores are used to personalize atrial fibrillation treatment

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An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1.251. Ivabradine fails to reduce occurrence of myocardial injury after noncardiac surgery in clinical trial

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Ivabradine did not reduce the occurrence of myocardial injury after noncardiac surgery (MINS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1.252. AI co-pilot boosts noninvasive brain-computer interface by interpreting user intent

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UCLA engineers have developed a wearable, noninvasive brain-computer interface system that utilizes artificial intelligence as a co-pilot to help infer user intent and complete tasks by moving a robotic arm or a computer cursor.

1.253. How pediatric brain tumors grow: Blocking a chemical messenger could offer new route to treatment

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The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors. Although this type of tumor is usually not life-threatening, the unchecked growth of tumor cells can disrupt normal brain development and function.

1.254. Scanner detects bedsores earlier, saving lives and costs

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In 2010, UCLA nursing professor Barbara Bates-Jensen traveled to Haiti to direct and provide wound care for victims of a 7.0-magnitude earthquake that had killed or injured more than half a million people and left 5 million displaced.

1.255. Binge gaming in kids associated with adverse mental, social and academic outcomes

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A team of Hong Kong researchers has found that binge gaming correlates with poorer social, academic, and mental health outcomes in schoolchildren, with distinct patterns by gender.

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