Worse outcomes with aspirin in high-risk chronic coronary syndrome patients requiring long-term anticoagulation: Trial

When I mention kids and nuts in the same sentence, some parents react like I've dropped the F-bomb, thanks to the association of nuts with two other F-words: fat and fear.

Ultra-processed foods (UPFs) have become public enemy number one in nutrition debates. From dementia to obesity and an epidemic of "food addiction," these factory-made products, including crisps, ready meals, fizzy drinks and packaged snacks, are blamed for a wide range of modern health problems. Some experts argue that they're "specifically formulated and aggressively marketed to maximize consumption and corporate profits," hijacking our brain's reward systems to make us eat beyond our needs.

Among low-risk patients with acute MI who underwent early complete revascularization and received one month of dual antiplatelet therapy (DAPT), P2Y12 inhibitor monotherapy was noninferior to continued DAPT for adverse cardiovascular and cerebrovascular events, while reducing bleeding risk.

Depression alters how people pursue rewards, but, conversely, whether depressive symptoms influence how people learn to avoid nonrewarding, unpleasant events is less clear.

A comprehensive analysis of nearly 29,000 patients with coronary artery disease (CAD) suggests that clopidogrel, a commonly prescribed blood thinner, is more effective than aspirin in preventing serious heart and stroke events, without increasing the risk of major bleeding.

"Unspecified," "altruistic" or "non-directed" kidney donation refers to a kidney transplant where the donor and recipient do not know each other. These donations are crucial to increasing the number of high-quality kidneys available, but ethical concerns and assumptions that they are inferior to 'specified' donations (usually from a family member or close friend) mean the practice is not widely adopted in many countries around the world.

Scientists at the University of Augsburg have discovered a particularly active subgroup of blood platelets that may cause heart attacks in people with coronary heart disease despite drug therapy. This discovery may open up new prospects for customized therapies. The research results are published in the European Heart Journal and were presented on August 31 at Europe's largest cardiology congress.

An invitation to attend a comprehensive screening examination for the early signs of cardiovascular disease (CVD) did not reduce all-cause death among men aged 60 to 64 years, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

Apixaban 2.5 mg twice daily significantly reduced symptomatic venous thromboembolism (VTE) recurrence, with a low risk of major bleeding, in patients with provoked VTE and enduring risk factors, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

Drug-coated stents and balloons were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in two trials in peripheral artery disease (PAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

A simple blood test could make asthma treatment more precise, more effective—and potentially more affordable. Researchers from Karl Landsteiner University of Health Sciences (KL Krems) and the Medical University of Vienna (MedUni Vienna) have developed a molecular allergy chip that detects allergic asthma in individual patients. The paper is published in the journal Allergy.

A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to findings published in Science Advances.

During pregnancy, the body becomes particularly vulnerable to chemical exposures that can affect both the mother and the developing fetus. These exposures—often from everyday sources like processed foods, packaging materials, and personal care products—introduce xenobiotic metabolites (XMs) into the body.

Mount Sinai researchers developed an AI model to make individualized treatment recommendations for atrial fibrillation (AF) patients—helping clinicians accurately decide whether or not to treat them with anticoagulants (blood thinner medications) to prevent stroke, which is currently the standard treatment course in this patient population. This model presents a completely new approach for how clinical decisions are made for AF patients and could represent a potential paradigm shift in this area.

A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent X-ray examinations and thus reduce the associated radiation, anxiety and costs.

An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

Ivabradine did not reduce the occurrence of myocardial injury after noncardiac surgery (MINS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

UCLA engineers have developed a wearable, noninvasive brain-computer interface system that utilizes artificial intelligence as a co-pilot to help infer user intent and complete tasks by moving a robotic arm or a computer cursor.