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How exercise helps the heart regain energy balance in heart failure

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  • 2025-07-02 01:28 event
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How exercise helps the heart regain energy balance in heart failure
Heart failure (HF) is a growing global health concern, affecting more than 64 million people worldwide. It develops when the heart can no longer pump enough blood to meet the body's demands, often due to long-term damage from other cardiovascular conditions.

2.027. Hidden bias may leave women and older adults underdiagnosed for HIV in Spain

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A recent study analyzes the extent to which HIV tests are conducted following the diagnosis of an HIV indicator condition (IC) in primary care, as recommended by the World Health Organization and the European Centre for Disease Prevention and Control. The article "Implicit bias in HIV testing based on indicator conditions in primary care: a population-based study in Catalonia, Spain, 2017 to 2021" was published in Eurosurveillance and led by researchers from the IGTP's research group Centre for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT) and IDIAPJGol.

2.028. PHOx: An innovative, safer polymer for implantable medical devices

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A scientific team from the University of Liège has just developed an innovative polymer, PHOx, which could significantly improve the safety of implantable medical devices, while being more environmentally friendly. This invention is the subject of an international patent application.

2.029. Understanding the role of pigmentation in hereditary hearing loss

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Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan. Using genetically engineered mice lacking the SLC26A4 gene, the researchers found that problems with melanin degradation led to its pathological accumulation in the inner ear, causing chronic inflammation and macrophage activation. These findings could inform new therapeutic strategies to minimize some forms of hereditary hearing loss.

2.030. Australian life expectancy inequality narrows, but disadvantaged areas still lag behind

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Australia has made progress in reducing socioeconomic inequalities in life expectancy since the late 2010s, according to new research from The Australian National University (ANU), setting the country apart from many other high-income countries.

2.031. Multiscale simulations successfully connect micro- and macro levels of brain activity

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Predicting how molecular changes affect the brain's overall activity is a major challenge in neuroscience. Many deep questions about the brain can only be understood by looking at several layers of brain activity at the same time—with a so-called "multi-scale" approach. For a long time, this had been considered out of reach.

2.032. Keeping brain-dead pregnant women on life support raises ethical issues that go beyond abortion politics

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Adriana Smith, a 30-year-old woman from Georgia who had been declared brain-dead in February 2025, spent 16 weeks on life support while doctors worked to keep her body functioning well enough to support her developing fetus. On June 13, 2025, her premature baby, named Chance, was born via cesarean section at 25 weeks.

2.033. Trump administration may cut funds to hospitals offering gender care to kids

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The Trump administration may cut off federal funding to hospitals that provide gender-related treatments to children and teens.

2.034. Conflicts of interest must be tackled to protect public health, argue researchers

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A new peer‐reviewed article by academics at the University of Bath warns that unless governments take urgent steps to address conflicts of interest with harmful industries—including tobacco, alcohol, ultra‐processed food, gambling and fossil fuels—efforts to prevent disease and protect public health will fail.

2.035. Ozempic-like drug significantly reduces frequency of chronic migraines in pilot study

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Migraines are a common ailment worldwide, affecting nearly 15% of the global population. At times, they can be debilitating enough to interfere with daily activities. Despite a multitude of treatment options, some migraine sufferers cannot find relief in available drugs. Others experience side effects that prevent the use of certain available migraine medications.

2.036. How exercise helps the heart regain energy balance in heart failure

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Heart failure (HF) is a growing global health concern, affecting more than 64 million people worldwide. It develops when the heart can no longer pump enough blood to meet the body's demands, often due to long-term damage from other cardiovascular conditions.

2.037. Unleashing potassium for better mitochondrial health and platelet biogenesis

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A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced platelet production, thus highlighting a key regulatory mechanism in thrombopoiesis.

2.038. Study reveals 33% gap in transplant access for UK's poorest children

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New research, presented at the ESOT Congress 2025, reveals persistent inequalities in children's access to life-saving kidney transplants across the UK. The study highlights how ethnicity, socioeconomic status, and gender significantly influence a child's likelihood of receiving a transplant.

2.039. Inhibiting enzyme could halt cell death in Parkinson's disease, study finds

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Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.

2.040. Delirium common for ICU patients after stroke

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Delirium affected 44% of critically ill patients in an Ohio medical center who were hospitalized after a recent stroke, according to new research published in the American Journal of Critical Care. Incidence rates were highest for patients with intracerebral hemorrhage (ICH), with 60% having delirium for at least one day.

2.041. First oral drug shows promise for Barth syndrome heart and muscle symptoms

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Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in Barth syndrome, a rare genetic disorder affecting 1 in 300,000 births worldwide with no current cure.

2.042. Scientists investigate spinal ligament development to understand scoliosis formation

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Scientists from Trinity College Dublin are assessing how the development of spinal ligaments provide mechanical stability and impact postural support in the spine—with a view to better understanding how developmental "missteps" may contribute to spinal deformations, such as the characteristic curved spines that develop in people with scoliosis.

2.043. How mosquito control could exacerbate public health disparities

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Special districts established to control mosquitoes in parts of Florida claim significantly more funding and expertise than county-run programs, finds a new analysis co-authored by a Cornell public health expert.

2.044. Moderna's new flu shot shows strong results in older adults

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Moderna's new flu vaccine, based on the same mRNA technology used in its COVID-19 shot, showed promising results in a major trial, the company announced Monday.

2.045. Why frequent nightmares may shorten your life by years

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Waking up from a nightmare can leave your heart pounding, but the effects may reach far beyond a restless night. Adults who suffer bad dreams every week were almost three times more likely to die before age 75 than people who rarely have them.

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