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By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an integrated gene signature for ferroptosis. They evaluated the associated genes in both mice and human liver injury systems, validating the potential use of iFerroptosis as a biomarker. By highlighting the role of ferroptosis in liver injuries, this study offers insights into unique therapeutic targets.
A research team has developed a diagnostic system that uses artificial intelligence (AI) to accurately identify the type of facial pigmented lesions and support laser treatment decisions. A paper on this study was published online in Cureus.
A team of researchers led by NYU Tandon School of Engineering's Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.
Minimizing opioid exposure during and after colorectal surgery can decrease long-term opioid use in some patients, according to new research by Mass General Brigham investigators.
Cellular communication between neurons within our brain is complex and busy, much like a USPS mailroom.
A recent study analyzes the extent to which HIV tests are conducted following the diagnosis of an HIV indicator condition (IC) in primary care, as recommended by the World Health Organization and the European Centre for Disease Prevention and Control. The article "Implicit bias in HIV testing based on indicator conditions in primary care: a population-based study in Catalonia, Spain, 2017 to 2021" was published in Eurosurveillance and led by researchers from the IGTP's research group Centre for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT) and IDIAPJGol.
A scientific team from the University of Liège has just developed an innovative polymer, PHOx, which could significantly improve the safety of implantable medical devices, while being more environmentally friendly. This invention is the subject of an international patent application.
Melanin can either protect or worsen hereditary hearing loss depending on genetic context, as reported by researchers from Japan. Using genetically engineered mice lacking the SLC26A4 gene, the researchers found that problems with melanin degradation led to its pathological accumulation in the inner ear, causing chronic inflammation and macrophage activation. These findings could inform new therapeutic strategies to minimize some forms of hereditary hearing loss.
Australia has made progress in reducing socioeconomic inequalities in life expectancy since the late 2010s, according to new research from The Australian National University (ANU), setting the country apart from many other high-income countries.
Predicting how molecular changes affect the brain's overall activity is a major challenge in neuroscience. Many deep questions about the brain can only be understood by looking at several layers of brain activity at the same time—with a so-called "multi-scale" approach. For a long time, this had been considered out of reach.
Adriana Smith, a 30-year-old woman from Georgia who had been declared brain-dead in February 2025, spent 16 weeks on life support while doctors worked to keep her body functioning well enough to support her developing fetus. On June 13, 2025, her premature baby, named Chance, was born via cesarean section at 25 weeks.
The Trump administration may cut off federal funding to hospitals that provide gender-related treatments to children and teens.
A new peer‐reviewed article by academics at the University of Bath warns that unless governments take urgent steps to address conflicts of interest with harmful industries—including tobacco, alcohol, ultra‐processed food, gambling and fossil fuels—efforts to prevent disease and protect public health will fail.
Migraines are a common ailment worldwide, affecting nearly 15% of the global population. At times, they can be debilitating enough to interfere with daily activities. Despite a multitude of treatment options, some migraine sufferers cannot find relief in available drugs. Others experience side effects that prevent the use of certain available migraine medications.
Heart failure (HF) is a growing global health concern, affecting more than 64 million people worldwide. It develops when the heart can no longer pump enough blood to meet the body's demands, often due to long-term damage from other cardiovascular conditions.
A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced platelet production, thus highlighting a key regulatory mechanism in thrombopoiesis.
New research, presented at the ESOT Congress 2025, reveals persistent inequalities in children's access to life-saving kidney transplants across the UK. The study highlights how ethnicity, socioeconomic status, and gender significantly influence a child's likelihood of receiving a transplant.
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.
Delirium affected 44% of critically ill patients in an Ohio medical center who were hospitalized after a recent stroke, according to new research published in the American Journal of Critical Care. Incidence rates were highest for patients with intracerebral hemorrhage (ICH), with 60% having delirium for at least one day.