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A new study led by researchers at Mount Sinai Health System has identified distinct biological signatures in patients with mild Crohn's disease, offering a potential pathway toward more personalized and less aggressive treatment strategies.
Research in the International Journal of Data Mining and Bioinformatics discusses a new approach to demand forecasting for the pharmaceutical retail sector based on an artificial intelligence model. The findings hold promise for improving accuracy in one of the industry's most persistent logistical challenges: managing sales that swing sharply during promotional periods. The new system works better than traditional models by distinguishing between routine demand and the short-term surges driven by marketing campaigns.
In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell's nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, eBIC director at Diamond, used cutting-edge cryo-electron microscopy to capture HIV-1 viral cores in the process of nuclear import—an elusive but critical step in the virus's life cycle.
It is a common belief that mental illness runs in families. While it is true that heredity plays a role, in reality, the vast majority of cases—such as schizophrenia, bipolar disorder, depression, and borderline personality disorder—occur in people without any known hereditary predisposition.
Children who carry a particularly high number of genetic variants associated with ADHD also have a statistically greater risk of experiencing severe neglect and childhood maltreatment.
When thinking about future events, optimists' brains work similarly, while pessimists' brains show a much larger degree of individuality. The Kobe University finding offers an explanation why optimists are seen as more sociable—they may share a common vision of the future.
New research from The University of Texas at Arlington reveals that social media platforms can play a potentially life-saving role for young people navigating difficult circumstances at home.
Cannabis use disorder (CUD) is associated with increased risk of benign salivary gland tumors, according to a research letter published online July 17 in JAMA Otolaryngology-Head & Neck Surgery.
Rural hospital closures directly impact the health of rural Americans by reducing access to care. New research from the University of Minnesota School of Public Health sheds light on another consequence of these closures: rising prices at "surviving" rural hospitals. This first-of-its-kind analysis shows that when a rural hospital closes, it eliminates a low-price, potentially more affordable hospital from the region. Moreover, commercial prices at nearby hospitals increased by 3.6% in the years following a closure.
For generations, women have relied on informal networks of friends, family and neighbors to navigate the complexities of birth and motherhood. Today, research is finally catching up to what generations of women have known: Peer support can be a lifeline.
People are diverse, and the environments they live in may influence them differently. This broad diversity increases the need for neuroimaging studies that collect data from large communities.
In a new JNeurosci paper, Julie Royo, from the Institute of Cerveau, and colleagues explored the neuroanatomy that underlies social dominance in nonhuman primates.
A comprehensive new Royal Life Saving Australia study has found a significant reduction in drowning rates, particularly among young children, but highlights continuing challenges among migrant and regional populations and in locations including rivers and beaches.
In a 2022 survey of 3,000 U.S. adults, more than one-third of respondents reported that on most days, they feel "completely overwhelmed" by stress. At the same time, a growing body of research is documenting the negative health consequences of higher stress levels, which include increased rates of cancer, heart disease, autoimmune conditions and even dementia.
An international research team led from Uppsala University has identified new mechanisms behind how the aggressive brain tumor glioblastoma spreads in the brain. Targeting the identified connection between the tumor invasion routes and the tumor cell states could be a potential new treatment strategy.
Artificial intelligence (AI) in health care is rapidly advancing beyond traditional applications. Autonomous AI agents are gaining significant attention for their potential to fundamentally transform medicine. However, researchers at the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology highlight a growing mismatch between the capabilities of autonomous AI agents and existing medical device regulatory frameworks in the US and Europe.
Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that these proteins can be detected in the plasma of people with the conditions.
Consumption of soft drinks, supplemented with white sugar, alters the DNA of gut bacteria and affects the host immune system. The good news? These effects are reversible.
There is certainly growing awareness of the damaging effects of overexposure to the sun, including skin cancers.