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Inaccuracies found in key studies for blockbuster heart drug ticagrelor

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  • 2025-06-20 06:00 event
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Inaccuracies found in key studies for blockbuster heart drug ticagrelor
In a follow-up investigation into the multibillion-dollar drug ticagrelor, The BMJ has uncovered fresh concerns, this time in key platelet studies used in its FDA approval.

3.062. Airborne fungal spores may help predict COVID-19 and flu surges

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Monitoring fungal spores in the outdoor air can predict surges in flu and COVID-19 infections, especially during the fall, according to a new study. The study is presented at ASM Microbe 2025 in Los Angeles.

3.063. AI scientists and doctors partner to understand who is at risk for persistent post-surgical pain

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One of the most common surgical complications is postoperative pain that persists long after the surgical incision has healed, striking anywhere between 10–35% of the estimated 300 million people worldwide who undergo surgery yearly.

3.064. Gut microbiome: A new frontier for chronic fatigue and long COVID management

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Imagine living with a persistent, debilitating fatigue that no amount of rest can alleviate, coupled with a constellation of other symptoms such as brain fog, pain, and sleep disturbances. This is the reality for millions suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Now, envision a similar struggle following a viral infection, a condition increasingly recognized as long COVID.

3.065. Africa battles to halt cholera cases as funding cuts hurt

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Health-funding cuts are wreaking havoc on many African countries' ability to gain control of diseases such as cholera, according to the continent's main health-advisory body.

3.066. #SkinnyTok rebranded eating disorders dangerously fast

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#SkinnyTok is dead. Or at least that's what TikTok wants you to believe after its recent ban of the hashtag promoting an extreme thin ideal. That might have appeased regulators, but it shouldn't satisfy parents of teens on the app. An army of influencers is keeping the trend alive, putting vulnerable young people in harm's way.

3.067. When data disappear: Researcher examines impact of limiting public health stats

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Tom McAndrew, a computational scientist and associate professor in Lehigh's College of Health, recently published a paper in The Lancet Digital Health, examining the consequences of rolling back public health data that researchers and health care providers rely on to make treatment decisions during the influenza season.

3.068. Human–AI collectives make the most accurate medical diagnoses, according to new study

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Artificial intelligence (AI) can effectively support doctors in making diagnoses. It makes different mistakes than humans—and this complementarity represents a previously untapped strength. An international team has now systematically demonstrated for the first time that combining human expertise with AI models leads to the most accurate open-ended diagnoses. Their paper is published in the Proceedings of the National Academy of Sciences.

3.069. Brain organizes visuomotor associations into structured graph-like mental schemes, study finds

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Graphs, visual representations outlining the relationships between different entities, concepts or variables, can be very effective in summarizing complex patterns and information. Past psychology studies suggest that the human brain stores memories and experiences following graph-like and structured patterns, specifically as a network of associations, also referred to as cognitive graphs.

3.070. Virtual reality could help stroke survivors regain movement

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A paper published in the Cochrane Database of Systematic Reviews has found that virtual reality (VR), when used in addition to standard therapy, can help stroke survivors regain arm movement. The findings suggest that VR could be a promising tool to boost rehabilitation efforts, particularly by increasing the amount of therapy patients receive.

3.071. Inaccuracies found in key studies for blockbuster heart drug ticagrelor

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In a follow-up investigation into the multibillion-dollar drug ticagrelor, The BMJ has uncovered fresh concerns, this time in key platelet studies used in its FDA approval.

3.072. Personalized cancer vaccines slow tumor recurrence in mouse models

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Using a newly discovered byproduct of dying cancer cells, University of Wisconsin–Madison researchers are developing personalized vaccines that could help keep aggressive tumors from recurring.

3.073. New technology detects breast cancer relapses up to five years in advance

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Altum Sequencing, a start-up supported by the C3N-IA Science Park at Universidad Carlos III de Madrid (UC3M) and specialized in oncology, has developed a tool to monitor treatment response in patients with solid tumors from a simple blood sample. This advance could represent a turning point in post-treatment follow-up.

3.074. Central adiposity increases the risk for urinary incontinence, finds study

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According to a recent study conducted at the University of Jyväskylä, Finland, body composition is associated with symptoms of pelvic floor disorders in middle-aged women. Larger fat mass increases the risk of stress urinary incontinence. The risk factors include larger fat mass, especially in the waist area and around visceral organs, as well as larger waist circumference and body mass index.

3.075. Alzheimer's disease research offers hope for finding therapeutic target that stops progression

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In searching for a possible therapeutic target to stop the progress of this disease, an international scientific team, led by researchers at the Department of Cell Biology, Genetics and Physiology of the UMA and also members of the Baglietto lab and the NeuroAD research group, has identified different factors involved in the propagation processes.

3.076. Alcohol alters gene function in the differentiating cells of the embryo, study finds

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Exposure to alcohol during the first weeks of embryonic development changes gene activity and cellular metabolism. In laboratory cultures, it was found that the first cells of the nervous system are the most sensitive to alcohol. This supports the recommendation to abstain from alcohol already when planning a pregnancy.

3.077. The quest to reinvent anesthesia

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Before 1846, surgery was a crude and brutal undertaking, typically performed on conscious patients lashed to their beds. Then a Boston dentist publicly demonstrated that the highly flammable chemical diethyl ether—commonly called ether—could render a patient unconscious and insensitive to pain. Overnight, surgery became a major player in modern medicine.

3.078. Mediterranean, fasting or DASH? Exploring promising metabolic benefits for management of MASLD

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Imagine a condition affecting nearly one-third of the global population, often silently progressing, and deeply intertwined with prevalent health issues like obesity and type 2 diabetes. This is metabolic dysfunction-associated steatotic liver disease, or MASLD, previously known as non-alcoholic fatty liver disease (NAFLD). It's characterized by an excessive accumulation of fat in the liver, which can lead to more severe liver pathologies, including inflammation, fibrosis, and even liver cancer.

3.079. Angolan operated by doctor 7,000 miles away in 'Africa first'

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A cancer patient in Angola was recovering Thursday after undergoing the first robotic surgery on the continent conducted remotely by a surgeon in the United States, according to the hospitals involved.

3.080. UK health service rejects costly, 'low benefit' Alzheimer's drugs

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The UK's state-run health service said Thursday it will not offer two new treatments for Alzheimer's disease, citing high costs and "too small" benefits.

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