Key mechanisms of enzyme involved in rare metabolic disease identified

Shorter-form messaging seems to be preferable for recruiting participants to enroll in clinical trials, according to a research letter published online June 25 in the Journal of the American Medical Association.

Exposure to trihalomethanes—especially brominated trihalomethanes—in residential community water supplies (CWS) is associated with an increased risk of chronic kidney disease (CKD), according to a study published online July 2 in JAMA Network Open.

Investigators have developed an artificial intelligence-assisted diagnostic system that can estimate bone mineral density in both the lumbar spine and the femur of the upper leg, based on X-ray images. The advance is described in a study published in the Journal of Orthopaedic Research.

A large prospective study published in Molecular Nutrition and Food Research reveals that a healthy plant-based diet is linked with a reduced risk of inflammatory bowel disease.

Research in Health Economics indicates that introducing school grades—with A as the highest grade and F as a failing grade—at younger ages may negatively affect children's mental health.

Teclistamab-cqyv is a T-cell-engaging bispecific antibody that targets multiple myeloma cells via the B-cell maturation antigen (BCMA) receptor. It received accelerated approval in 2022 for patients treated with four or more lines of prior therapy based on results from the Phase I/II MajesTEC-1 clinical trial.

A mental health hack designed to promote mental well-being could shift how teenagers view themselves—according to new research from the University of East Anglia.

A compound found in psychedelic mushrooms may have antiaging properties. Researchers at Baylor College of Medicine have found that psilocybin, the active compound in psychedelic mushrooms, may extend both cellular and organismal lifespans.

An innovative partnership between a health system and local congregations in neighborhoods with high need that provides individual companionship to older adults has found significant reductions in loneliness and a corresponding reduction in emergency department visits.

A research team led by Prof. Gu Hongcang and Zhang Fan from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has identified a novel long non-coding RNA (lncRNA)-driven regulatory network that plays a central role in colorectal cancer (CRC) progression and immune response.

The human brain is made up of billions of nerve cells (neurons) that communicate with each other in vast, interconnected networks. For the brain to function reliably, there must be a fine balance between two types of signals: Excitatory neurons that pass on information and increase activity, and inhibitory neurons that limit activity and prevent other neurons from becoming too active or firing out of control. This balance between excitation and inhibition is essential for a healthy, stable brain.

The herpes simplex virus type 1 (HSV-1), which affects almost two‑thirds of the world's population and is generally associated with oral herpes, may cause painful cold sores or fever blisters around the mouth.

Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, are developing a panel of biomarkers for the early detection of Alzheimer's disease and for distinguishing it from other types of dementia using blood tests. The research project is based on the genotype analysis of 500 volunteers with and without the disease.

Exposure to a common fungal molecule can reprogram immune cells in the lungs, causing them to overreact to infection-like signals and worsen lung damage, according to new research.

Got a sore throat and the sniffles? The recent rise of rapid at-home tests has made it easier to find out if you have a serious illness like COVID-19 or just a touch of spring allergies. But while quick and convenient, these at-home tests are less sensitive than those available at the doctor's office, meaning that you may still test negative even if you are infected.

Gaines County, the epicenter of the massive Texas measles outbreak that began in January, no longer has ongoing measles transmission, public health officials said on Tuesday.

When Israelis think about health, they may picture hospitals, doctors, or the rising cost of prescription drugs. But a new integrative study by Jordan Hannink Attal (Hebrew University and the University of Melbourne) and Prof. Yehuda Neumark (Hebrew University) suggests the most important factor may be much closer to home—literally.

Researchers from the University of Florida Emerging Pathogens Institute and Texas A&M University recently gathered their resources to investigate the potential of vector-borne transmission of Chagas in Florida. The 10-year-long study, published in PLOS Neglected Tropical Diseases, used data from Florida-based submissions, as well as field evidence collected from 23 counties across Florida.