Local ancestry inference method could improve accuracy of genetic testing and patient diagnoses

Adults with ADHD who recognize and regularly use their personal strengths report better well-being, improved quality of life and fewer mental health difficulties, according to a new international study.

NSAID-exacerbated respiratory disease, N-ERD, is associated with measurable changes in concentrations of lipid mediators involved in inflammation and pain modulation, a new study shows. Plasma concentrations of two key endocannabinoid-related lipids, arachidonoylethanolamide (AEA) and oleoylethanolamide (OEA), were significantly reduced in patients with N-ERD, compared to healthy controls.

Imagine walking into your pharmacy, handing over your prescription and having it denied. Now imagine that the reason is not insufficient insurance coverage or the wrong dose, but a pharmacist who personally objects to your medication. What right does a pharmacist have to make moral decisions for their patients?

Is it an achievable goal to remain mentally sharp while aging, or is it a pipe dream?

Once synonymous with hippies and hallucinatory experiences, psychedelic drugs are now being explored for their medical potential. The stigma of that era resulted in research being suppressed by drug laws, yet with mental health treatments hitting limits, scientists have returned to this controversial corner of medicine.

Patients with newly diagnosed glaucoma who have less wealth or reside in rural communities are less likely to receive standard glaucoma care compared to wealthier patients, according to a recent multi-institutional study published in JAMA Ophthalmology.

Researchers at the First Affiliated Hospital of the University of Science and Technology of China claim that an in vivo CD8 T-cell-targeted lipid nanoparticle carrying CD19 CAR mRNA (HN2301) generated transient CAR T cells that rapidly depleted B cells and reduced disease activity in five patients with treatment resistant systemic lupus erythematosus.

Researchers at Western and the University of Calgary have discovered how HIV hides in different parts of the body by embedding itself into the DNA of cells in a tissue-specific manner, offering new insights into why the virus is so difficult to eliminate and cure—even decades after infection and treatment.

A new thesis from Karolinska Institutet studied how mental health problems run in families. Using nationwide Swedish registers, the researchers followed millions of parents and their children over decades, revealing several important findings about how and why mental health problems pass from parents to children, and importantly, how to interrupt this cycle.

An international research team led by the University of Cologne has discovered an antibody that could advance the fight against HIV. The newly identified antibody 04_A06 proved to be particularly effective in laboratory tests. It was able to neutralize 98.5% of more than 300 different HIV strains, making it one of the broadest antibodies against HIV identified.

Neuroinflammation damages neurons and can contribute to diseases like Alzheimer's. Cannabidiol (CBD) has anti-inflammatory properties, which suggests that it could combat neuroinflammation in Alzheimer's.

The verdict is in! Scientists have cleared mosquitoes of any responsibility in the spread of Lyme disease, and say ticks are solely to blame for the pervasive disease.

A commercial robotic leg could potentially benefit both higher- and lower-mobility amputees, University of Michigan roboticists have shown for the first time.

Engaging in creative experiences like music, dance, visual arts, and even specific video games can slow brain aging and promote healthier brain function, says a new international Global Brain Health Institute (GBHI) study published in Nature Communications.

The cold and flu season is beginning amid conflicting guidance on vaccination and the use of acetaminophen—a common fever-reducing drug sold under brand names such as Tylenol—during pregnancy. Adrienne Antonson is a professor of animal sciences at the University of Illinois Urbana-Champaign who studies the immune response during pregnancy and prenatal neurodevelopment. She discussed what her research has found about infection during pregnancy, how it affects development and effective ways to treat and prevent it in an interview with Lauren Quinn, the assistant director of research communications for the College of Agricultural, Consumer and Environmental Sciences at the U. of I.

Researchers have developed a new laser-based technique that targets pancreatic ductal adenocarcinoma (PDAC) while leaving healthy tissue intact. PDAC is the most common type of pancreatic cancer and the third leading cause of death related to cancer.

People with Sweet's syndrome often wake up with a fever, body aches, and blisters on their neck, limbs and face. Also known as acute febrile neutrophilic dermatosis, it is an inflammatory skin disease marked by severe symptoms and elevated counts of white blood cells.

October is Breast Cancer Awareness Month, a time to spotlight a disease that will affect hundreds of thousands of Americans this year. In the U.S., a new case of breast cancer is diagnosed about every two minutes, with more than 317,000 women and 2,800 men expected to receive the diagnosis in 2025, according to the Susan G. Komen Foundation.